How have human-environmental entanglements changed in the Gulf of San Miguel, Darien, Panama, from the first traces human practices through to the present?

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

The eighth issue of the JLGC explores the diverse and interdisciplinary research on our multifaceted relationship with animals which is currently taking place, re-examining the relationship between humans and animals, and the definitions involved.

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

When do fire making tools appear in prehistory, and how might the use of these tools manifest in the archaeological record?

How can zebrafish research help to understand and fight human cancer?

Event co-sponsored by the IAPDD, Leiden University, and the Australian Research Council project “Digital Death and Immortality”

Understanding the temporal modes of digital mapping.

Does foreign aid promote human rights?

In Humanity’s End As A New Beginning, Emeritus Professor Mineke Schipper reflects on myths about ‘the end’.

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Analysis of drug adversity

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

The factors that dynamically sculpt the inter-regional correlation of brain patterns are poorly understood. Here, we test the hypothesis that they are shaped by the catecholaminergic neuromodulators norepinephrine and dopamine.

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

How do digital technologies affect both Asian societies and the methods we use to study them? Conference in Leiden on 23-25 May 2016. Deadline abstract submission: 15 February 2016.

Researchers from Leiden and Delft have found a way to look inside early-modern bookbindings. An x-ray technique has allowed them to search for remains of medieval manuscripts hidden inside the bindings. After the Middle Ages many manuscripts were recycled, their pages pasted inside bookbindings to provide…

This summer school focuses on the emergence of sexual orientation, gender identity (SOGI) and intersex issues in different areas of international law, such as human rights law, refugee law, international economic law, and international criminal law. Further information for this summer course will be…

Eduard Fosch-Villaronga, Associate Professor at eLaw, contributed to 'Cyber–Physical–Human Systems', a book exploring the latest developments in interactions between cyber–physical systems and humans.

Lecture

Imagining Urban Complexity introduces passionate and critical perspectives on the link between the humanities and urban studies.

Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…

As part of Metamorfoze, the national digitalization project for the preservation of paper heritage, journals of The Van Vollenhoven Institute’s library have been digitized.

On Thursday 20 May 2021, Tania Li delivered the annual Van Vollenhoven Lecture.

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

The manual analysis of remotely-sensed data is a widespread practice in local and regional scale archaeological research, as well as heritage management.

The archaeology domain produces large amounts of texts, too much to effectively read or manually search through for research. To alleviate this problem, we created a search system (called AGNES), which combines full text search with entity and geographical search.

On 29 November 2022, Jan Aart Scholte and colleagues presented the project 'Digital Data: Polycentric Governance Perspectives' at the United Nations Internet Governance Forum in Addis Ababa. Click here to find out more about the event.

Collecting as much information as possible about administering a new medicine to people can save a lot of money.

Vocal learning is a trait shared by songbirds and humans. It is also a trait that is restricted by the brain rather than by a species' vocal apparatus. In this dissertation, functional MRI is employed in both species in order to explore potential common neural mechanisms underlying the ability to develop…

You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.

The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.

Three scholars of the Faculty of Humanities, Ahmad Al-Jallad, Thomas Fossen, and Tsolin Nalbantian, have received a Veni grant to implement their research plans over the coming years.

If an algorithm has to learn to understand language, simply having a lot of data doesn’t help much. Like us, a computer has to learn the language in interaction with others. Tessa Verhoef is fascinated by how this interaction works.

Promotores: G.R. de Snoo, B. Sinsin, Co-Promotor: H.H. de Iongh

On May 15th, from 15.15 to 17.00 in the Vossiusroom, Leiden University Libraries will host a program on web-archiving and digital archives of Chinese communities in the Netherlands and Indonesia.

The University of Göttingen is pleased to announce its annual international digital palaeography summer school. The summer school is intended as an intensive training programme for graduate students, in both traditional Latin palaeography and codicology, and in the latest digital technologies applicable…

To celebrate the end of the semester the Science and Humanities Buddy Programme organised a barbecue together, which has become a small tradition. The barbecue marks the third co-organised activity between the two Programmes and helps to bring international and Dutch students together. The Buddy Programme…