10,000 search results for “development ” in the Public website
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Magnetic Resonance Imaging of the Adult Zebrafish
Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…
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About ENPAIR
ENPAIR, the European Network on Psychoeducational Assessment, Intervention and Rehabilitation, has its founding roots in Europe, but brings together scientific researchers and evidence-based working practitioners from countries all over the world.
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Urban Space and Urban History in the Roman World
This volume investigates how urban growth and prosperity transformed the cities of the Roman Mediterranean in the last centuries BCE and the first centuries CE, integrating debates about Roman urban space with discourse on Roman urban history.
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Case study Käte van Tricht (1909-1996)
The Organ Art of the first female German concert organist and Bremen Cathedral organist and
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Building a Phonological Inventory - Feature Co-occurrence Constraints in Acquisition
The Feature Co-occurrence Constraint theory proposed in this dissertation provides a means to capture the development of the language learning child's segment inventory.
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The use of Deep Learning in the automated detection of archaeological objects in remotely sensed data
Generally the data from remote sensing surveys - the scanning of the earth by satellite or aircraft in order to obtain information about it - is screened manually in archaeology. However, constant monitoring of the earth's surface causes a huge influx of data of high complexity and high quality. To…
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Debunking Myths about China: The Determinants of China’s Official Financing to the Pacific
Bob van Grieken and Jaroslaw Kantorowicz published an article in the journal Geopolitics which explores the determinants of China's official financing of Pacific Island states.
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Team 7 Graduation
Our bachelor’s degree programmes do not always align with the level of the master’s degree programmes. In order to tackle this, this team will examine how we can improve that alignment and how the graduation trajectory can play a role in this.
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Wapishana bilingual education
Evaluating processes of Wapishana-English Bilingual Education Programme in Guyana.
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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Crossing boundaries in improvised music
Developing new methods for performing improvised music
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Routledge Handbook of Interdisciplinary Research Methods
Illustrations of the challenges and rewards of doing and representing interdisciplinary research through the methodological developments of 50 experienced researchers.
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Regional Aviation Safety Organisations: Enhancing Air Transport Safety through Regional Cooperation
Aviation safety is of global concern. Yet 43% of countries worldwide lack the expertise and administrative capacity to ensure effective safety oversight of the aviation activities for which they are responsible under international law.
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Global China’s Human Touch?
On 17 January 2024 Ying Wang successfully defended a doctoral thesis and graduated.
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Squaramide-based supramolecular polymers: from self-assembly to in vivo application
The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.
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Our Research
From basic science to real-world interventions
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Foreign investment in Africa
English The purpose of this research is to identify and examine the challenges faced by African States in the field of foreign investment with a view to contribute not only to the academic debate, but also to foster awareness and develop the capacities of these States with regard to the drafting, negotiation…
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Archaeological Prediction and Risk Management
Alternatives to current practice
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Curriculum for Turnaround Professionals
Development of a curricumlum for EACTP's certification for turnaround professionals.
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Searching for the sibling of the earth
Are there other planets like the earth, and will there also be life? Astronomers study planets around stars other than the sun, with the aim to find out what kind of gasses their atmospheres are made up with.
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: Prof.dr. T. Hankemeier, Co-promotor: T.H. Reijmers
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Chemical tools to monitor and control human proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Self-Adjusting Surrogate-Assisted Optimization Techniques for Expensive Constrained Black Box ProblemsBagheri, S.
Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.
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Islamic courts and women's divorce rights in Indonesia: the cases of Cianjur and Bulukumba
This book presents the results of a research about the Islamic courts of Cianjur in West Java, and Bulukumba in South Sulawesi and the role they play in local divorce practices.
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Breaking the witches' spell: towards steering the soil microbiome for volatile-mediated control of the root parasitic weed Striga
Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.
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Tlamatiliztli: la sabiduría del pueblo nahua. Filosofía intercultural y derecho a la tierra
The aim of this research is the systematic analysis of the wisdom coined by Nahua people of Mexico, based on the historical sources and archaeological evidence, but also in the knowledge developed by contemporary indigenous communities and the contributions of indigenous scholars.
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LC-Impact
How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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ADAPTED
The ADAPTED (Alzheimer's Disease Apolipoprotein Pathology for Treatment Elucidation and Development) project is a major new initiative to investigate an area of Alzheimer's Disease (AD) research which has previously received little attention. The project aims to improve understanding of the function…
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Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
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Bolivia at the Crossroads: Politics, Economy, and Environment in a Time of Crisis
As Bolivia reels from the collapse of the government in November 2019, a wave of social protests, and now the impact of Covid-19, this book asks: where next for Bolivia?
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Between Fear and Power: Kompas, Indonesia's Most Influential Daily Newspaper
Wijayanto defended his thesis on 17 January 2019
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About the Programme
The dynamic between research and professional practice is a theme that runs through the programme at the Dual PhD Centre and represents all academic disciplines at the University. The programme has been especially developed for our Dual PhD candidates, who come from different backgrounds and professions.…
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The iconography of Avalokiteśvara in Java
Sofia Sundström defended her thesis on 5 March 2020.
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Knowledge Discovery and Data Mining from patient experience repositories
This project develops a scientific method to extract clinically relevant new information from patient forum websites that discuss patient experiences concerning e.g. medication, nutrition, co-morbidities, genetic factors etc.
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Skills
It is generally accepted that a university education is about more than knowledge transfer alone. Alongside knowledge and understanding, students should develop the skills required to apply this knowledge and understanding.
- Mathematical Institute
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Secular-religious self-improvement
Jasmijn Rana demonstrates in the article 'Secular-religious self-improvement: Muslim women’s kickboxing in the Netherlands' that young Muslim women who kickbox develop agentive selves by challenging gender norms and living out their religious subjectivities.
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Buddhist Astrology and Astral Magic in the Tang Dynasty
Jeffrey Kotyk defended his thesis on 7 September 2017
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Products and downloads
Here you can find products and research tools developed by the Navigation Lab Leiden
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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Target Discovery
The goal of target discovery is to identify and validate proteins and biological pathways that are involved in the disease process. Modulating these target proteins and pathways with small molecules, therapeutic proteins or other biomolecules (e.g. mRNA) could deliver an effective and safe drug or v…