Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Mapping the neural mechanisms underlying social motivations of adolescents and adults

The handbook is a wide-ranging survey of a crucial period in prehistory during which many social, economic, and technological changes took place. Written by specialists in the field, the book provides coverage both of the themes that characterise the period, and of the specific developments that took…

Oxidation is a common degradation pathway that affects therapeutic proteins and peptides during production, purification, formulation, transportation, storage and handling of solid and liquid preparations. In the present work we review the scientific literature about structural and biological consequences…

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

On Monday 13th March, the YAL organized an interfaculty lunch meeting together with the Leiden Teacher Academy (LTA) about teaching.

The aim of this research project was to increase understanding of which collaborative learning approaches already exist in conservatoire education, and how implementation of collaborative learning could be supported.

This dissertation investigates ikat from the eastern Indonesian islands from a uniquely technical perspective, including design analysis of asymmetry and microscopy.

On April 4th, Zohreh Shiamizadeh succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Zohreh on this great result.

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Descriptive linguistics at LUCL covers documentation and descriptive analysis of lesser-studied languages as well as typological and historical comparison.

This dissertation presents a grammar of Khwarshi, a Nakh-Daghestanian language.

In this dissertation, Boethius’ mathematics and logic and their roles in philosophy are reassessed, and on the basis of these, the connections between mathematics and logic in Boethius and their applications to theological or philosophical topics are explored.

How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?

Counter-Discourse in Zimbabwean Literature is a study of specific aspects of counter-discursive Zimbabwean narratives in English. In discussing the selected texts, my thesis is based on Terdiman’s (1989) the postcolonial concept of counter-discourse.

In citizen science projects, citizens and scientists work together to develop new scientific knowledge.

Studying in Leiden and The Hague comes with a number of facilities. These include use of the university library, login details for Brightspace and the possibility of study guidance. On this page you can read all about it and find useful links.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

In 2019, LUGO started a petition demanding an ambitious sustainability vision for 2030. This petition was formulated based on what LUGO deemed achievable rather than based on the restrictions of the present. We believe that sustainability should be one of the core values of the next central policy…

The main aim of the project is to collect and update on a regular basis bibliometric and patent indicators that can be used to underpin and inform analyses pursued at the European Commission (EC) to assess European and national scientific and technological performance.

What are the foundations of the regulation of blasphemy, and in which manner, in legal as well as in extra-legal terms, has blasphemy developed over the last decades?

Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken

Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.

This book presents a comprehensive description of the grammar of Logba, one of the fourteen Ghana-Togo Mountain (GTM) languages spoken by approximately 7,500 speakers on the South-Eastern frontier of the Ghana-Togo border. It is the outcome of fifteen months research in Logba speaking communities.

When researching languages in historical context, our goal is to understand the nature of linguistic variation in the past, and explain the extent to which the socio-cultural context of bygone times contributed to shaping linguistic variation and change.

Psychoeducational Assessment, Intervention and Rehabilitation (PAIR) publishes high quality articles on theoretical and empirical research regarding psychological and psychoeducational assessment, intervention, and rehabilitation in all areas related to cognitive and socio-emotional development.

This series provides a venue for scholarly work—research monographs and edited volumes—that advances our understanding of the history of slavery and post-slavery in any period and any geographical region. It fills an important gap in academic publishing and builds upon two relatively recent developments…

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

This Call for Proposals covers a wide range of research incubator ideas to stimulate research careers of early career female researchers at FGGA. Research incubator ideas may include various research themes and could concern different types of research projects.

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

This specialisation offers a structured, challenging curriculum balancing substantive and skills-oriented courses, including a number of elective seminars, plus a research thesis.

In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.

The specialisation teaches you analytical frameworks and skills for managerial decision making. Internships help you decide whether you want to choose a career in industry or Physics research.

The master programme International dispute settlement and arbitration consists of 8 courses and a thesis. Read more information about the programme structure.

The SCS courses train you in practical and theoretical aspects of science communication. Internships help you decide whether you want to choose a career in science communication or Physics research.

In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.

The master’s specialisation Theoretical Physics consists of 120 European Credit Transfer System (EC) points and includes electives (60 EC) and two research programmes (30 EC each).

Tax scandals, like the Panama Papers, the Paradise Papers, and the Pandora Papers, have made taxation a major topic of public debate. Learn more about this in the new minor Tax and Society: Building a Sustainable and Fair Tax System.

After graduation you have a lot of opportunities: academics are highly sought after in Dutch secondary education or mbo teaching. You can also aim for a management position or work as a researcher within the field of Astronomy.

The master's specialisation Astronomy Research at Leiden University students focus on astronomical data analysis using models and large-scale simulation, combining the fields of Astronomy, Physics, Mathematics and Computer Science.

After graduation you have a lot of opportunities: academics are highly sought after in Dutch secondary education or mbo teaching. You can also aim for a management position or work as a researcher within the field of Life Sciences.

With an ever-increasing amount of data generated worldwide, industry, governments and academia highly welcome professionals with specific knowledge and skills to handle big data.