This dissertation investigates the rural communities of the Cananefates in the period of 50 to 300 AD.

How can Staphylococcus aureus bacteria subvert the host immune system?

This week sees the first edition of the textbook Mouse&Manuscript published online. Mouse&Manuscript is a collection of interactive lessons on codicology and oriental manuscripts. Its aim is to stimulate teaching on codicology in and outside of the classroom, and to contribute to the disclosure of Leiden…

How can we manipulate the biotic and abiotic environment to increase thrips resistance in tomato and chrysanthemum? More specifically we ask: How can plant secondary metabolites that are not soluble in water be delivered to plants in seed coating or root dipping treatment? Can bacteria be used to…

Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

Negative perceptions of ambiguous social cues, social performance and physical arousal in socially anxious youth

Promotor: W.Th.F. den Hollander

What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?

We consider the propagation of electrical signals through nerve fibres.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Promotor: Prof.dr. M. Ubbink

What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Which plant leaf characteristics are involved in thrips resistance in tomato?

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

The Collective Experience of Empathic Data Systems (CEEDs) consortium developed novel integrated technologies that support experiencing, analysing and understanding of very large datasets.

Which compounds and microorganisms that live near and inside plant roots are beneficial? Can we use this knowledge to improve the health and growth of crop plants?

We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

Can metabolomic profiling be used to predict resistance against insect herbivores in plants?

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?

Andrew DJ Shield (History) and Ann Marie Wilson (Leiden University College) have been awarded a seed grant for their project, “Transnational Gay/Lesbian Activism since the 1960s.” Granted: €3000.

How do plant defense genes get activated?

Lecture, Com(parative) Syn(tax) Series

How can zebrafish research help understanding human diseases?

To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.

Which immune mechanisms are involved in host defense against Staphylococcal infection?

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. H. Leirs (Univ. Antwerpen), Co-promotor: H.H. de Iongh

Promotor: Prof.dr. P.G.L Klinkhamer

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

How do mycobacteria subvert the defenses of host immune cells?

On September 21st Magdalena Jozwiak, researcher at eLaw - Center for Law and Digital Technologies, gave a presentation of the e-SIDES project at a lunch event organized within the Interaction Between Legal Systems (ILS) research theme.

Lecture