380 search results for “smit barrie repair” in the Public website
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Working at the Faculty of Science
Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.
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Excavating Fossilized Data
A cross-cut analysis of the ties between university research and fossil industries.
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Valorization of Scientific Knowledge: Philosophy, History and Policy
This project aims to situate the current policy concept of ‘valorization of scientific knowledge’ in historical and epistemological perspectives. Conceptual understanding of the utility of scientific practices is developed in dialogue with historical analyses of the politics of knowledge in European…
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Chemokine signaling in Tuberculosis and Salmonella infection
Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?
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A Social History of Painting Inscriptions in the Ming Dynasty (1368- 1644)
Wenxin Wang defended her thesis on 26 October 2016
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Essays on African languages and linguistics : in honour of Maarten Mous
This book celebrates Maarten Mous, professor of African Linguistics at Leiden University.
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Visualizing the classics: Reading surimono and kyōka books as social and cultural history
D.P. Kok defended his thesis on 10 October 2017
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Research
The department carries out research in all fields of IP law. The research is a part of the faculty research programme Coherent Private Law.
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Working at the Faculty of Science
Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Sustainability Research Cluster
The Sustainability Research Cluster fosters dialogue and collaboration among anthropologists and sociologists researching aspects of socio-cultural, ecological, and economic sustainability in and affiliated with the Institute of Cultural Anthropology and Development Sociology. It also seeks to stimulate…
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Restoration of Sterrewacht reaches highest point
The restoration of the Sterrewacht is proceeding well and is expected to be completed by the end of the year. On Thursday 11 March, the highest point was reached with the restored domes being replaced on the roof.
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Mechanisms underlying mutational outcomes of DNA double-strand break repair
PhD defence
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Specificity and side-effects of mutagenesis by CRISPR/Cas9 -induced breaks in plants
Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?
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Impaired barrier of inflammatory skin diseases
Focus in skin research
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
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Collaborative Crisis Management Before and During International Summits
Peak Performance: Collaborative Crisis Management Before and During International Summits. This comparative case study probes into conditions for collaborative governance in the security organisation of international summits.
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Machine learning and computer vision for urban drainage inspections
Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotor: Prof.dr.ir. T.H. Oosterkamp, N. de Jonge
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Key publications
Key publications of the Skin Barrier and Vaccination group.
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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About Faculty of Science
The Faculty of Science is located at the Leiden Bio Science Park. It was founded more than two centuries ago and currently, more than 8000 people are working and studying at the eight institutes.
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Key publications
Key publications of the Cardiovascular Pharmacology group
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Participants
The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).
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Remote participation in a hybrid classroom: Interacting with students with chronic illnesses
There are about 35,000 students with chronic illnesses in the Netherlands. If they cannot receive education in the classroom, they may be able to do so from home or a hospital with hybrid education. The question in this study is: how can interaction with the teacher and fellow students be promoted?
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Radicals in arithmetic
Promotor: Prof.dr. P. Stevenhagen, Co-promotor: Prof. dr. B. de Smit
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The intertopian mode in the depiction of Turkey-originated migrants in European film
On 7 September 2023 Didem Durak Akser successfully defended a doctoral thesis and graduated.
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“The Binnenhof” a contested court. History, housing and politics in The Hague, 1813-2013
This project examines the meaning of this historical place, and the way it has been used by the political institutions that have had their seat there.
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Tracing Shumi: Politics and Aesthetics in Modern Japanese Literary Discourse and Fiction
On 30 January 2024 Jurre van der Meer successfully defended a doctoral thesis and graduated.
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Dimensions of student participation: participatory action research in a teacher education context
This thesis investigated the extent to which participation of school students in decision-making processes can be achieved, including through participatory action research (PAR) in teacher education.
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Light Weighed: On the Statistics and Systematics of Weak Gravitational Lensing
In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.
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Inverse problems for universal deformation rings of group representations
Promotor: P. Stevenhagen, Co-promotores: B. de Smit, F. Andreatta
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Escher and the Droste effect
Artful Mathematics: The Heritage of M. C. Escher
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Steady-State Analysis of Large Scale Systems
Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma
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Utility Spots, Science Policy, Knowledge Transfer and the Politics of Proximity
How we think about and act on the usefulness of scientific research has epistemological and political implications: what knowledge consists of, how it comes about and to what ends. In this dissertation, I situate the usefulness of scientific research in concrete places for knowledge exchange. The exchange…
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Biomimetic Copper Catalysts for the Electrochemical Oxygen Reduction Reaction
Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.
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Acknowledgements and contributors
Rembrandt & Leiden University: The Bigger Picture commemorates the 444th anniversary of Leiden University and the 2019 Rembrandt Year. Our special thanks go to Germanisches Nationalmuseum (Nuremberg), The Leiden Collection (New York), Museum De Lakenhal (Leiden), Mauritshuis (The Hague), Rijksmuseum/Musée…
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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Words and Laments: A Narratological Analysis of Esmāʻil Fasih’s War Novel, The Winter of 1983 (Zemestān-e 62)
Saeedeh Shahnahpur defended her thesis on 13 September 2016.
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Individualized dosing of aminoglycosides and glycopeptide antibiotics in (morbidly) obese patients (AMIGO)
Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).
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Intellectual Property Law
The IP Law (Intellectual Property Law) department provides education and conducts research in the field of intellectual property law.
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Low-temperature spectroscopic studies of single molecules in 3-D and on 2-D hosts
Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…
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Unspinning chromatin: molecular mechanisms of chromatin remodeling
How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?
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The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.
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Multi-objective Evolutionary Algorithms for Optimal Scheduling
Multi-objective optimization is an effective technique for finding optimal solutions that balance several conflicting objectives. It has been applied in many fields of our world, because practical problems usually have more than one desired goal. For example, developing a new vehicle component might…
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Ancient Egyptian Footwear: An Archeological Analysis
The wealth of shoes, sandals and other footwear from ancient Egypt is poorly understood due to lack of research. This is remarkable, because from the very beginning of Egypt’s long history footwear served practical as well as more spiritual purposes.
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Cleveringa Dallaire Critical Conversation Series
In the fall of 2021, Cleveringa professor Roméo Dallaire and world experts shared their thoughts about PTSD, children’s rights, war crimes, humanitarian law, and peacekeeping in a series of conversations about leadership and moral dilemma during times of conflict and crisis.
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Memory, Modernity, and Children’s Literature in Japan
On 1 September 2022 Afke van Ewijk successfully defended a doctoral thesis and graduated.