1,399 search results for “brain function and dysfunction” in the Public website
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Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and
Source: Mol Psychiatry (2015)
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Determinants of and Interventions in Chronic Fatigue.
What are the most important perpetuating factors of chronic fatigue and chronic fatigue syndrome, and which interventions are effective in influencing these factors?
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Clinical Neuropsychology (MSc)
In the specialisation Clinical Neuropsychology, part of the Master in Psychology, you will focus on fostering clinical and scientific skills based on a solid theoretical background as well as practical training in neuropsychology and (clinical) neuropsychological research.
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Like me or else...
Nature, nurture and neural mechanisms of social emotion regulation in childhood
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Deciphering myeloid (progenitor) cell function and communication in (tumor) tissues
PhD defence
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Professor calls for more focus on brain impairment in offenders
Maaike Kempes believes more attention should be paid to non-congenital brain injuries in suspects. This may partly explain their criminal behaviour.
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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What happens to the brain when you become a mother?
May 12 is Mother's Day in many countries. Becoming a mother is no mean feat: brain scientist Elseline Hoekzema has shown that a woman's brain changes drastically during pregnancy. She explained how in TV show De Kennis van Nu.
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Navigating Between Principle and Pragmatism: The Roles and Functions of Atrocity-Related United Nations Commissions of Inquiry in the International
On 7 November 2018, Catherine Harwood defended her thesis 'Navigating Between Principle and Pragmatism: The Roles and Functions of Atrocity-Related United Nations Commissions of Inquiry in the International Legal Order'. The doctoral research was supervised by Prof. dr. L.J. Van den Herik and Prof.…
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‘Brain scanners are bringing about a revolution in neurolinguistics’
Brain scanners have radically changed neurolinguistics. They are increasing our understanding of how the brain processes language. Professor Niels Schiller has produced a standard work on this.
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Anne-Laura van Harmelen appointed to new chair Brain, Security and Resilience
Leiden University will appoint Dr Anne-Laura van Harmelen as Professor of Brain, Security and Resilience at the Institute of Education and Child Studies with effect from 1 September 2020. She will focus on the brain in relation to the development of transgressive behaviour and its prevention and tre…
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observe a single particle of light? (And what does that say about our brain?)
Hoping to learn something about the human brain, Leiden researchers are creating a setup to shoot single photons, particles of light, into someone’s eye. ‘The eye is a passageway to the brain.’
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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Deciphering the link between Iron and Brain Disease
Aceruloplasminemia is a very rare, genetic disease accompagnied with iron accumulation that causes movement disorder and brain damage at early age.
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Leiden delves into the mystery of the brain and language
The Leiden Institute for Brain and Cognition (LIBC) is concentrating increasingly on research into the role of the brain in language development. The institute has now set up the LIBC Language website that brings together all the information on this research.
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Parental criticism hurts: a glimpse inside the adolescent brain
It may seem as though adolescents do as they please, but they are more sensitive to their parents’ opinions than they would appear. The adolescent brain reacts strongly to parental criticism or praise. These are the results of a study by an interdisciplinary research group of psychologists and neuroscientists…
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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NWA grant for research into iron nanoparticles in the brain
Physicists Lucia Bossoni and Martina Huber have been awarded an NWA Ideeëngenerator-grant for research into iron nanoparticles in the brain. These nanoparticles may be linked to air pollution and Alzheimer's disease.
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Volunteers needed for brain study in resilience research project
Why do some people with adverse childhood experiences develop mental health conditions whereas others do not? A Leiden research project is looking for volunteers aged between 18 and 24 to help us understand more about human resilience.
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Pilgrims came to Leiden for ‘brain training’
The Pilgrims to America exhibition at Museum De Lakenhal inspires reflection. How far do you go in the quest for freedom? It focuses on the Pilgrims’ relationship with the University and which knowledge they took with them from Leiden.
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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Lara Wierenga
Faculteit der Sociale Wetenschappen
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Marcella Pavias
Faculteit der Sociale Wetenschappen
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Jiska Peper
Faculteit der Sociale Wetenschappen
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.
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polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking strategies for polymeric micelles
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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How do parents’ brains react to feedback about their child?
Parents appear to be extremely sensitive to feedback they receive about their child. Just how sensitive depends on the (‘rose-tinted’) glasses through which they look at their child. All this can be seen in the brain. Neuroscientist Lisanne van Houtum and her Leiden colleagues published on this issue…
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How does the brain of Japanese speakers choose pronunciation?
The way in which written language is processed in the brain is a hot topic in cognitive research. Cognitive psychologist Rinus Verdonschot studied a Japanese script in which a single character can have up to three possible pronunciations. He discovered that all three are simultaneously activated in…
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Holger Hoos in NRC about AI brain drain
Dutch newspaper NRC contacted four Dutch universities regarding the brain drain in the field of Artificial Intelligence (AI) that is going on in the Netherlands.
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Overstimulated? Artist pictures her brain with cacophony of colours
'With this artwork, I want to give the audience a glance into my overstimulated brain and that of other people with autism', says Jasmijn den Hoed. The Faculty of Social and Behavioural Sciences is exhibiting her artwork 'Overstimulated' in the restaurant near the blue wall during Autism Week 25 March…
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Lecture “Speed in Music, Brain and Body” at Café Chercher
ACPA’s PhD candidate and composer/flutist Ned McGowan will give a lecture at Café Chercher on March 27 called Speed in Music, Brain and Body.
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Granted STW Project: Energy Efficient Computer-Brain Interaction
The STW project Energy Efficient Computer-Brain Interaction (principal investigator for LIACS: dr. T.P. Stefanov) has been granted. Funding for LIACS: 1 PhD student + travel/equipment budget, project duration: 4 years.
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Programme structure
The master's specialisation Clinical Neuropsychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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How brain disorder models are like the Night Watch
Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.
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Stimulating the gut–brain nerve can influence emotion
Stimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions. This research study by psychologists Katerina Johnson and Laura Steenbergen is published in the journal Neuroscience.
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Artificial brain helps Gaia satellite catch speeding stars
With the help of software that mimics a human brain, ESA’s Gaia satellite spotted six stars zipping at high speed from the centre of our Galaxy to its outskirts. This could provide key information about some of the most obscure regions of the Milky Way.
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'Mobile phone in 2035 as powerful as our brains'
Within 20 years, intelligent machines will play a major role in society. ‘Selfdriving cars will be 90% safer than human-driven cars and will change transportation globally,’ says artificial intelligence scientist Bart Selman of Cornell University. He gave the first Ada Lovelace lecture of the Leiden…
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Brain research shows punishing is more rewarding than helping
Just imagine: you see someone being treated unfairly. Do you find it more rewarding to help the victim or punish the perpetrator? Research by Leiden psychologist Mirre Stallen indicates that punishing is more rewarding. Publication in JNeurosci.
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Best friends forever? How the adolescent brain reacts to good friends
During adolescence, some young people have stable best-friend relationships, while others change best friends frequently. Developmental psychologist Lisa Schreuders has studied the brains of young adolescents: ‘It seems that friendships in your early years can have consequences for your friendships…
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Children's stories as inspiration for an artificial brain
Max van Duijn, Assistant Professor at the Leiden Institute of Advanced Computer Science (LIACS), has been awarded a Veni grant for his research into children's empathy. The ability to empathise can be studied by telling stories. This process, known as 'Theory of Mind' or ‘mindreading’, can provide important…
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Nanoparticles can aid in stroke therapy
Tiny selenium particles could have a therapeutic effect on ischemic brain strokes by promoting the recovery of brain damage. Pharmacologists, including Alireza Mashaghi from the Leiden Academic Centre for Drug Research discovered that selenium nanoparticles inhibit molecular mechanisms that are responsible…
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Lipid chain length reduction correlates with the skin barrier function in atopic eczema patients and inflammation plays a role in the altered
Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)
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Why the brain needs to get out and about
We are all at home in familiar surroundings. Not only is this boring but it can also have a negative influence on our learning, explains cognitive neuropsychologist Judith Schomaker. ‘Discovering new environments gets our brain learning and remembering. We are now missing this stimulus.’
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Hester Ruigendijk
Faculteit der Sociale Wetenschappen
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Style and function of female images in prints by Keisai Eisen (1790–1848) ideals of beauty and gender in the Late Edo Period consumer society
On the 15th of July Sawako Takemura successfully defended a doctoral thesis and graduated.
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Cognitive Neuroscience (research) (MSc)
In the track Cognitive Neuroscience we focus on the investigation of the psychological, computational, and neuroscientific bases of human cognition by means of mind and brain research.
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Language and self-regulation in XXY
The role of language in self-regulation and social behavior in children with an extra X chromosome
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel