What is the role of the noradrenergic system in human cognition?

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.

Control of infectious diseases poses continuous challenges for human health.

This book presents a comprehensive description of the grammar of Logba, one of the fourteen Ghana-Togo Mountain (GTM) languages spoken by approximately 7,500 speakers on the South-Eastern frontier of the Ghana-Togo border. It is the outcome of fifteen months research in Logba speaking communities.

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

How does FoxP1 affect auditory perception on a behavioural and genomic level?

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

How do cognitive, motivational, and affective processes interact to select actions?

The programme group Research Methods and Statistics offers methodological support in many projects in the field of education and child studies.

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Host-Microbe Interactions is one of the four research themes of the Institute of Biology Leiden.

Reconstructing language history and prehistory in the context of the Indo-European language family.

Although there has been an increase in the research into brain function and dysfunction in relation to stress and emotions, there are still many unanswered questions.

Completing your Master’s in Biology gives you an internationally recognised degree which you can follow up with a PhD track. With your acquainted skills, you’re a much requested professional in and outside research.

This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…

The master’s specialisation Evolutionary Biology at Leiden University investigates biology at all levels. The specialisation includes genomics, functional developmental genetics, paleobiology, behavioral biology and evolutionary ecology.

Leiden University offers you several services related to career orientation and job application skills.

The two-year Bioinformatics programme (120 EC) includes mandatory core courses and electives, as well as a Master's Thesis Research Project.

On the 2nd of July, Axel Palmér successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Axel on this achievement!

Are you interested in taking up an extra challenge during your master’s programme? Have you thought about developing your personal leadership style?

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

- How to deconvolute metabolic mixture of precursors and products by biontransformation? - How to optimize the reaction conditions to produce bioactive compounds in biotransformation? - What is the effect of co-treating fungi or bacteria for biotransformations?

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Majid Khan, born and raised in Pakistan, left his wife and daughter behind to do research in Leiden. After obtaining his PhD, the Netherlands has taken a special place in his heart. ‘Biking in the rain and wind was weird. But I loved it.’

Hermen Overkleeft and his colleagues Gideon Davies (University of York) and Carme Rovira (University of Barcelona) will receive a 9.1 million euros Synergy Grant from the European Research Council. Together, they will form the Carbocentre Synergy team for research into enzymes that work on glycans:…

Vera van Noort has been appointed Professor in the field of Computational Biology within the Faculty of Science at the Institute of Biology from the 1st of February 2017. Van Noort’s expertise is in bioinformatics and her research focuses on the computational analysis of large-scale biological data…

In 2022, many of our staff and students won fantastic prizes and were awarded important research grants.

Research in the POD-group addresses all features of random phenomena – modelling, structuring, analysis, control, optimisation – and covers both fundamental and applied aspects.

This study offers a comprehensive but balanced grammatical analysis of Ik (Icetod), Northeast Uganda’s last thriving Kuliak language.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

The members of LUXs develop and validate new methods and algorithms for analysing data, and apply these in a wide range of problems. Their research ranges from multidisciplinary applications to proving mathematical theorems.

The Great Rift Valley in Africa is a real treasure trove for discovering early human fossils. The fossils found in this part of Africa have determined our view of human evolution. But was the Great Rift Valley really the place where evolution took place or just a place where fossils are well preserved…

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

How can you use robots and automatic recognition of microscopic images to test the effect of drugs exceptionally quickly?

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

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Is it possible to synthesize industrially relevant compounds in a sustainable manner through the use of light-capturing cyanobacteria?

How did toxin genes evolve from harmless physiological genes?

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

This dissertation provides a description of Konso, a Cushitic language spoken by about 250,000 speakers in the South-West Ethiopia.

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.

Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?

Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.