983 search results for “brain function and dysfunction” in the Public website
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For students
We teach several courses in the domain of Mind, Brain, and Education.
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LIBC Sylvius Lectures and Colloquia
The LIBC organizes Sylvius Lectures and Colloquia for scientists and students about brain & cognition.
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Overview Former Public Scientific Days
Yearly, the LIBC organizes a public event to share scientific research in the field of brain & cognition
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ENIGMA-Anxiety Working Group
Together with researchers from over the world, the ENIGMA-Anxiety Working Group endeavors to unravel the neurobiology of anxiety disorders and related constructs.
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Applied Neuroscience in Human Development (MSc)
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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Contact
The Brain and Education Lab is located in the Faculty of Social and Behavioural Sciences of Leiden University.
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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From oscillations to language
On the 17th of January, Sarah Von Grebmer Zu Wolfsthurn successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sarah on this achievement!
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Magnetic Resonance Microimaging of Alzheimer's Disease
Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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Observing what cannot be observed: computational electrochemistry from carbon to hydrogen
In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.
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Hydrogen dissociation on metal surfaces
Promotor: G. J. Kroes
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Research methods
Because we cannot directly ask babies about what they know or what they are thinking about, we must find smart and baby-friendly ways to figure it out! Below you can read about the different methods that we typically use in our studies.
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‘Maybe interdisciplinarity could function as a way to change the university’
This year, in a three-part symposium series, we are exploring how interdisciplinary collaboration can be promoted at the university. In the second session in March, the attendees discovered that understanding your rhythm and perspective is essential when embarking on an interdisciplinary project.
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
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Roy de Kleijn: ‘Fetching a glass of water is extremely difficult for a robot’
Training a robot in a real-life environment is more or less impossible. Computer scientist and psychologist Roy de Kleijn switched to training in a simulated, virtual one instead. ‘You do have a reality gap, but the more precisely you train the robot, the better it is in practice.’ His inspiration:…
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Choosing health: how do we encourage that?
Fundamental research teaches us how our brain decides to eat one more sweet, instead of doing exercise. A public information campaign about healthy lifestyle has little impact on the decision, as Professor of General Psychology Bernard Hommel is aware. However, he does know what works. But the question…
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Topic: Aging and neuropsychological rehabilitation
Cognitive decline (amongst other problems with attention, concentration, memory) is a common symptom in patients with a variety of brain disorders and has been related to healthy ageing as well. People suffering from cognitive deficits are often significantly hampered in their day-to-day functioning…
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Membership LIBC
All brain and/or cognition researchers from Leiden University or the LUMC or colleagues seeking collaboration in this field are most welcome to join the LIBC!
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Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands
Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.
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Unraveling the Neural Basis of Self-Esteem in Adolescent Depression
What are the social and neural mechanisms that contribute to fluctuations in self-esteem in healthy adolescents and adolescents with depression?
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Neurofibromatosis Type I
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Linking soil microbial community dynamics to N2O emission after bioenergy residue amendments
Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.
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Ternate Malay: Grammar and Texts
This book is the first grammar on Ternate Malay, a local variety of Malay spoken on the island of Ternate, North-Moluccas, Indonesia.
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Tracing interactions in the indigenous Caribbean through a biographical approach
Much attention has been paid to the exchange of objects, ideas, and people in the Caribbean. Networks of interaction connected local communities across pan-regional scales, shaping indigenous socio-political integrations and their responses in colonial situations. This work examines the poorly understood…
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Make it and Break it: the cycle of pottery
A study of the technology, form, function, and use of pottery from the settlements Uitgeest-Groot Dorregeest and Schagen-Muggenburg 1, Roman Period, North-Holland, the Netherlands
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Storytelling and material culture around the Peace Palace in The Hague
Perception of material culture, design and digital knowledge applications
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More laws, more problems? The role of (Roman) law in society according to Cornelius Tacitus
Whether implicitly or explicitly, we all have ideas about how the law is supposed to function, whose interests it should represent, and what role it should play in society. This project explores the ways in which these questions are addressed in the works of the Roman historian Publius Cornelius Tacitus…
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Variation and change in Abui: The impact of Alor Malay on an indigenous language of Indonesia
On the 23rd of September, George Saad successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates George on this achievement!
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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Structural Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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MOOC: The Importance and Power of Music in our Society
Online cursus The Importance and Power of Music in our Society
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Changing minds in social anxiety: A developmental network approach to neurocognitive bias modification
Which adolescents are more at risk of developing social anxiety disorder later in life?
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Influence of dissociation on the neural correlates of Emotional Working Memory in Borderline Personality Disorder
How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?
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Solving problems in your head and in the world
Until recently, the role of external information processing in intelligence has rarely been investigated quantitatively or experimentally. A group of researchers from Erasmus University Rotterdam, Leiden University, GGZ Rivierduinen, and University of Edinburgh measured in a new way how and when people…
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AI in Neuroscience: Development of Methods to make Personalized Predictions for Migraine and Stroke from E-Health Sensor Data
The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Stochastic and Deterministic Algorithms for Continuous Black-Box Optimization
Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.
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Neurovascular Imaging Markers of Brain Aging
PhD defence
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Developmental Psychology (research) (MSc)
The Developmental Psychology specialisation of the Research Master’s in Psychology offers a strong theoretical background to provide the varied knowledge-base needed for a thorough understanding of emotional and cognitive development across childhood and adolescence.
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Participate
The researchers of the Brain and Education Lab are always conducting or starting new research projects in the field of learning and brain development. For this they are often looking for children, adolescents and adults between 8 and 30 years old who want to help and participate. Several research projects…
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LIBC Support
The LIBC is a network focusing on science valorisation and outreach, stimulating interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition. Get to know the support team.
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Spatial (3-D) CNS drug distribution in vivo
Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Experiments on the Modular Nature of Word and Sentence Phonology in Chinese Broca's Patients
This book investigates the effects of brain lesions in the left hemisphere, specifically Broca's area, on the production and perception of vowels, of word tones and of the linguistic use of sentence melody.
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Topic: Spatial thinking
Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…