Advanced biotechnology allows us to select or alter the genetic makeup of human embryos. What limits do we impose on biotechnological intervention in nature and the human body? And whose call is that?

The aim of this project is to determine in which cases uncertainty statements resulting from a Bayesian statistical analysis can be trusted.

Willemijn Heeren has, together with dr. Lei He (Department of Linguistics, Tübingen & Center for Forensic Phonetics and Acoustics, Zürich), received a research grant from the International Association for Forensic Phonetics and Acoustics to start a pilot project on “Between-speaker variability in dynamic…

Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.

With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

PhD defence

Correctly interpreting the patterns of fire evidence in the archaeological record will illuminate the origin of human fire use.

Our object is to identify and characterize transcription factors involved in lignocellulosic biomass degradation in the filamentous fungus Aspergillus niger.

The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology.

Can epigenetic changes explain associations between early life stress and health outcomes?

Which traits did change due to the invasion process of plants and how do these traits contribute to the invasiveness of such species. What is the role of carbohydrate accumulation? What is the function of carbohydrate accumulation in plants? Is genetic variation depleted in invasive species under se…

The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

The SNP genotyping line offers flexible genotyping for small and large projects at affordable price and high quality. The use as SNPs as molecular markers is very versatile and can be used for a wide variety of scientific questions ranging from paternity analysis, conservatuion genetis towards QTL…

The information below concerns courses that our group teaches in Leiden. 

An international mega-analysis on the neurobiological link between inhibited temperament and social anxiety disorder

In science, it is of vital importance that multiple studies corroborate the same result. Researchers therefore need to know all the details of previous experiments in order to implement the procedures as exactly as possible. However, this is becoming a major problem in neuroscience, as animal studies…

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

The Biology programme offers 4 research-oriented specialisations corresponding with the research themes within the three institutes involved. You can choose a more practical-oriented specialisation if you would like to combine Biology with education, management business, or science communication.

Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.

Lecture

Studies in Early Near Eastern Production, Subsistence, and Environment, vol.16. Edited by Noriyuki Shirai.

We warmly welcome late abstracts for Poster Communications! Late abstracts submission closes on the 1st of August 2022.

At LUCL, researchers aim to contribute to a comprehensive and informed perspective on the human past.

The Latin language is a descendant of the widespread Indo-European family of languages. Recent ancient genetic studies have helped shed light on the likelihood that the Indo-European languages spread into a Europe that had already been populated by farmers for thousands of years.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

Cell-based medicinal products (CBMPs) show great promise when it comes to the treatment of genetic disorders. However, there is limited knowledge about CBMP stability during their production, storage, and administration to patients. The main focus of my research is the characterization of CBMPs using…

Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:

Through courses and research projects, you are trained by experts in the field.

At LUCL, researchers aim to contribute to a comprehensive and informed perspective on the human past.

The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…

The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…

Lecture

Research at the MCBIM group is comprised of the following research themes:

Dutch Title:

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

Research at the Catalysis and Surface Chemistry group is comprised of the following research themes:

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

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Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency. That is what research by PhD candidate Julia Hillger shows. She defends her PhD dissertation Take it Personal on Thursday 7 December.

PhD defence

PhD defence

PhD defence

How do macrophages and neutrophils contribute to metastatic onset?

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.