10,000 search results for “leiden” in the Public website
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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Unveiling the nature of giant radio galaxies
The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.
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Brain and Education Lab
The Brain and Education lab is a research group in the Institute of Education and Child Studies at Leiden University in the Netherlands. We use a Developmental Cognitive Neuroscience approach to study the development of complex cognitive processes involved in learning and academic skills such as reading…
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Osteosarcoma: searching for new treatment options
Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen
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External Knowledge Absorption in Chinese SMEs
Today, knowledge is the most crucial element to stimulate organizational competitiveness and economic development.
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Hot Nanoparticles
Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.
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Centre for Late Antique and Medieval studies
The Centre for Late Antique and Medieval Studies (LAMS) is an academic initiative housed at the Leiden University Institute of Philosophy. It brings together researchers and academics working on one or more aspects of late antiquity and medieval studies, across the fields of philosophy, history, theology,…
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Veenendaal, How Smallness Fosters Clientelism: A Case Study of Malta
Political scientist Wouter Veenendaal (Leiden University) provides an in-depth case study of clientelism in Malta, the smallest member state of the European Union. He reveals that not only that patron–client linkages are a ubiquitous feature of political life in Malta, but also that the smallness of…
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On topological properties of massless fermions in a magnetic field
Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.
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Dancing with the Stars
This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.
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Women behind the scenes
Considering the fact that for a long time women were not allowed to participate either in university life nor in academia, women found different ways they could be included.
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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Two-photon luminescence of gold nanorods: applications to single-particle tracking and spectroscopy
Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.
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Faculties
There are different ways in which the faculties of Leiden University keep in touch with their alumni.
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Assessing global regionalized impacts of eutrophication on freshwater fish biodiversity
Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Excavations at Tell Sabi Abyad – Prehistoric Investigations in the Balikh Valley, Northern Syria
Balikh Valley Archaeological Project Monograph 1 - BAR International Series 468
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Never-Neverland Revisited: Malay Adventure Stories
This study presents a re-evaluation of Malay adventure stories.
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Histories Connected
Histories Connected seeks to explore social, cultural, and political issues that connect people of Asia, the Middle East, Africa, the Americas, and Europe throughout different periods of time.
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Disruptive Conflicts in Computopic Space
Can you imagine a radically different world? In our times dominated by neoliberal capitalism, we seem to lack not only viable alternatives, but also the capacity to envision anything outside of the status quo.
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Dutkiewicz, Casier & Scholte (eds.), Hegemony and World Order
Does hegemony—legitimated rule by dominant power—have a role in ordering world politics of the twenty-first century? If so, what form does that hegemony take: does it lie with a leading state or with some other force? How does contemporary world hegemony operate: what tools does it use and what outcomes…
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De gemaskerde krijger : de menpō in de 16e en 17e eeuw
Bas Verberk defended his thesis on 6 September 2016
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Toxicity, bioaccumulation and trophic transfer of engineered nanoparticles in the aquatic environment
The findings in this thesis improve the understanding of 1) the relationship between exposure characteristics and toxicity of ENPs, 2) the joint toxic action of ENP mixtures and the comparison to metal salt mixtures, 3) how NOM affects the individual and joint toxicity of ENPs, 4) the extent of trophic…
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Individual guidance
Didactics
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Sustainable campus
Leiden University is working on a green, circular campus, with a significant reduction in energy consumption by 2050 as its goal, as elaborated in the Route Map Energy Transition Buildings, published in 2022.
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Princes and Prophets: Democracy and the Defamation of Power
On 1 June 2022, Tom Herrenberg defended the thesis 'Prosecutorial Discretion in International Criminal Justice'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. B.R. Rijpkema.
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Statistical learning for complex data to enable precision medicine strategies
Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.
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Recognition of Foreign Bank Resolution Actions
Op 17 November 2020, Shuai Guo defended his thesis 'Recognition of Foreign Bank Resolution Actions'. The doctoral research was supervised by Prof. R.D. Vriesendorp and Prof. M. Haentjens.
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Information Diffusion Analysis in Online Social Networks based on Deep Representation Learning
With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.
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Investigations of Radiation Pressure: Optical side-band cooling of a trampoline resonator and the effect of superconductivity on the Casimir
This thesis consists of two subjects, that are both a consequence of radiation pressure.
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CRISPR Cas-induced targeted mutagenesis with Agrobacterium mediated protein delivery
The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.
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For students
We teach several courses in the domain of Mind, Brain, and Education.
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On quantum transport in flat-band materials
The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.
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Chemical synthesis of fragments of galactosaminogalactan and pel polysaccharides
The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.
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Global Challenges
Global Challenges is the research programme of the Leiden Institute of Cultural Anthropology and Development Sociology.
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Rechter over Grenzen
On Tuesday 19 December 2017 Anneloes Kuiper-Slendebroek defended her doctoral thesis 'Rechter over Grenzen' which deals with the application and interpretation of international law in Dutch private law. Supervisor is Martijn Polak, co-supervisor is Jeroen van der Weide.
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Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
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Macrophage activation and cholesterol accumulation in atherosclerosis development
Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck
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The Great Collapse
Promotor: Prof.dr. S.F. Portegies Zwart
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Diversity and distribution of octocorals and scleractinians in the Persian Gulf region
Promotor: E. Gittenberger, Co-promotores: B.W. Hoeksema; L.P. van Ofwegen
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Towards a greater understanding of the presence, fate and ecological effects of microplastics in the freshwater environment
This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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Cultural Production
This research network aims to create a shared platform for debate and dialogue on the broader theme of cultural production and exchange across different area specializations and historical periods.
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Mechanism-based inhibitors and probes for neuraminidases
Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.
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The Rationale of Publicity in the Law of Corporeal Movables and Claims
On 24 juni 2021, Jing Zhang defended his thesis 'The Rationale of Publicity in the Law of Corporeal Movables and Claims'. The doctoral research was supervised by Prof. H.J. Snijders and J.A. van der Weide.
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Maurits de Jongh, Is Political Liberalism Self-Defeating?
Political scientist Maurits de Jongh (Leiden University/Sciences Po) argues that political liberalism is self-defeating as a framework of justification for liberal conceptions of justice. He explores how the framework's self-imposed criterion of acceptability in the eyes of all reasonable citizens leads…