How do humans construct their self?

Specific fatty acid-sugar molecules allow leprosy bacteria, among others, to hide from our immune system. How exactly is not entirely clear. Hessel van Dijk, who received his PhD on 13 October, replicated the molecules, helping to solve a piece of the puzzle. Van Dijk's dissertation is titled: Synthesis…

PhD defence

Using brain imaging to discover the area in the brain that recognizes emotion.

PhD defence

Below you can read about studies we have carried out in the past.

PhD defence

PhD defence

PhD defence

The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny…

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.

Basketry, cordage and textiles made of plant fibers or bark are rarely preserved in the archaeological record. By means of experimental archaeology and microwear analysis, we obtain indirect evidence about this important craft.

Promotores: A.H. Meijer, H.P. Spaink

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

On December 11th, Andreea Geambasu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Andreea on this great result.

On May 31st, Bobby Ruijgrok succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Bobby on this great result.

How do mycobacteria subvert the defenses of host immune cells?

Honorata Mazepus and Jaroslaw Kantorowicz are assistant professors at the Institute of Security and Global Affairs. Mazepus and Kantorowicz are one of the authors of this article in Nature on the role of national identity on public health support during global pandemics.

How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?

This study looks at population response to government containment strategies during initial stages of the COVID-19 pandemic in four high-trust Northern European countries–Denmark, Germany, the Netherlands, and Sweden–with special emphasis on expressions of governmental trust.

This thesis investigates how the assessment of circular economy (CE) at the macro-economic level can be facilitated and promoted⁠.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

The project aims to develop an escape room-style game to teach students cyber crisis management and prepare them for real-world cybersecurity challenges

Considering Mesoamerican Precolonial books as material objects

Making sensitive data reusable through synthetic data generation

To construct catalysts that can produce fuels from CO2 innumerable times, we need to learn much more about how catalysis works. Irene Groot is conducting groundbreaking research into catalysis at the atomic level.

We are developing the conceptual framework, which is new to this taxonomic group, and evaluate the current state of the art with respect to all critical parameters and transfer functions for a fully developed Population Consequences of Acoustic Disturbance (PCAD) model.

Can epigenetic changes explain associations between early life stress and health outcomes?

Development & demonstration of low environmental impact innovation and optimization practices in pharma production.

In science, it is of vital importance that multiple studies corroborate the same result. Researchers therefore need to know all the details of previous experiments in order to implement the procedures as exactly as possible. However, this is becoming a major problem in neuroscience, as animal studies…

Numerous beads and pendants of amber, jet and bone have been found in Dutch Neolithic and Bronze Age context, both in settlements and in graves. Because ornaments are personal items, they are closely linked with people’s identity.

Case-studies on use-wear analysis of prehistoric flint tools

Music can affect how we feel, think, and behave. But how do we learn about the specifics of people's responses to music so that we can apply this to health and well-being? By looking at characteristics of the music, as well as the differences between listeners, we hope to better understand as well as…

Research of the Methodology & Statstics unit of the Institute of Psychology at Leiden University.

Develop a tool to assess land tenure, access to land and, and land tenure conflict in Timor-Leste

Due to the almost complete disappearance of the archive of the Old Dutch West India Company (WIC, 1621-1674) not much is known about the ships and crews of this company. In this project we start the reconstruction of this basic information making use of new digital humanities techniques to extract this…

If an algorithm has to learn to understand language, simply having a lot of data doesn’t help much. Like us, a computer has to learn the language in interaction with others. Tessa Verhoef is fascinated by how this interaction works.

A full overview of MacBio PhD Theses.

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

IT lawyer Eduard Fosch Villaronga wants to promote diversity and inclusiveness in AI research. And that's really important, because he has observed how artificial intelligence - from Twitter to walking robots - is prejudice in terms of race, gender and sexual orientation.

This is an Erasmus+ International Credit Mobility project of the Faculty of Humanities with the University of Hyderabad.

It has been argued that the Internet presents numerous new opportunities for crime, including homicide. So far, empirical scholarly research in this domain is rather limited. In order to discover how perpetrators have used the Internet in the homicides they have committed, we conducted an international…