709 search results for “genetics he modification” in the Public website
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Molecular Pharmacology
In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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On the representation of quantity: how our brains shape language
This project investigates properties of quantity expressions across languages from the perspective of how quantity is represented in the human brain.
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The Silk Road Language Web
A linguistic prehistory of the Tarim Basin in Northwest China
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Information activities
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Jaap van den Herik wins Humies Award 2014
The paper Genetic Algoriths for Evolving Computer Chess Programs by Omid E. David, Jaap van den Herik, Moshe Koppel, Nathan S. Netanyahu has won the Humies Award 2014 (human-competitive results produced by genetic and evolutionary computation).
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Effects of glufosinate-ammonium on off crop vegetation
Description of Effects of glufosinate-ammonium on off crop vegetation.
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Admission requirements
To be eligible for Molecular Genetics and Biotechnology at Leiden University, you must meet the following admission requirements.
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Wrestling with SUMO proteins
The work done by SUMO proteins in the cells of our body is of vital importance. Molecular cell biologist Alfred Vertegaal has been studying these proteins for nine years, first with a Veni subsidy and then with a prestigious Vidi subsidy.
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Vici grants for four Leiden researchers
Four Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Academic Research (NWO).
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LCCP Working seminar spring 2022
The seminar is dedicated to the work-in-progress of Leiden Centre for Continental Philosophy staff and doctoral students. The paper is sent in advance and discussed in the meeting. The seminar is open to all. Venue: Lecture room or zoom.
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Biogeochemical Biographies
A multiple isotope approach to human-animal dynamics in the Lesser Antilles across the historical divide
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Learning from the past
Leiden archaeologists investigate how people in the past impacted their environment. Together with scientists, environmental scientists, and humanities experts, they use this information to draw conclusions about the present – and show what we can learn from it for the future.
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Techniques en philosophie
Many stimulating philosophical analyses have been written on contemporary technology; this book examines on the contrary how changes in contemporary technological environment have been reflected onto philosophy itself. The book shows how technological changes have marked a number of key concepts of…
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Attentional processing of itch and pain
This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.
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Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
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Solid State NMR and modelling of photoinduced energy and electron transfer
Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…
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Formulation and Characterization of Vaccines
Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…
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Fine Mechanical Department
What is the Fine Mechanical Department?
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Mapping Sex-by-genotype Interactions in Brain Functions
Fatemeh (Simin) Tabassi Mofrad has recently received a project grant (€ 25,000) from LUF/Gratama Foundation for her ideas in investigating sex-by-genotype interactions in brain functions. She has a multidisciplinary research perspective which enables her to look at research issues from different angles.…
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Ahmed Mahfouz: 'The mystery of brain diseases, unravelled cell by cell'
Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.
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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Eighteenth-Century Cholón
The main purpose of this book is to give a description of the Cholón language as represented in the Arte de la lengua cholona (ALC), a colonial grammar written in 1748 by a Franciscan friar, named Pedro de la Mata. The ALC was transcribed by Fray Gerónimo Clota in 1772. This grammar is kept in the British…
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Galactofuranose biosynthesis in the filamentous fungus Aspergillus niger
This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.
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Development & Disease in Plant Sciences
Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…
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C.J. Kok Jury Award for Thesis of the Year
Isotopes on exoplanets, a more efficient memory for data centres or new molecules that work against the Zika virus and HIV. Which PhD candidate has written the most impressive dissertation of 2023? The jury of the C.J. Kok Jury Award faces the challenging task of deciding that. Meet the nominees of…
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LED3 Drug Discovery Case Studies
To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.
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Research
Research framework CIAS
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Why Leiden University?
We are committed to provide you a meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Tuition fees
Your tuition fee depends on a number of factors, such as your nationality and your previous Dutch higher-education qualifications.
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Biology (MSc)
The master’s programme Biology at Leiden University offers seven specialisations ranging from Cell Biology to Molecular Genetics. The programme prepares you for a career in research within or outside academia.
- Admission & Application
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Student life
Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.
- About this minor
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Programme structure
The research master's specialisation Developmental Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.
- Admission & Application
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Research
Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…
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BAT: Breaking the Transmission of Anxiety in the Family
Parents may pass anxiety onto their offspring by exposing them to anxious behaviors in novel situations. Just as the parents’ anxious signals lead to anxiety, parents’ confident signals can ward off anxiety in the offspring. This project is seeking a new way to break anxiety transmission in the family…
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HURP: Helsinki Urban Rat Project
How humans and rats cohabit the cityscape and what consequences this has for both sides of the conflict?
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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The scientists behind LED3
LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.
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Biomedical Sciences (MSc)
In this master programme you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme Biomedical Sciences relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…
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Second layer of information in DNA confirmed
Leiden theoretical physicists have proven that not only the genetic information in DNA determines who we are, but also DNA’s mechanics. Helmut Schiessel and his group simulated many DNA sequences and found a correlation between mechanical cues and the way DNA is folded. Publication in PLoS One.
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Are modern humans simply bad at smoking?
Scientist looked for the genetic footprint of fire use in our genes, but found that our prehistoric cousins - the Neanderthals - and even the great apes seem better at dealing with the toxins in smoke than modern humans.
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Phyto-pharmaceuticals and gene targeting
We exploit secondary metabolites of plant to develop pharmaceutical compounds and we genetically modify plant genomes to improve crops.
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Hybrid zones: a quick guide by Ben Wielstra
Ben Wielstra studies hybrid zones, regions in which distinct populations of organisms meet, mate and produce genetically admixed offspring. In the journal Current Biology, he introduces hybrid zones in an accessible way.
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Leiden-Delft-Erasmus, VPRO and Unesco launch online learning experience
Mind of the Universe is a series of portaits of worldwide leading scientists broadcasted summer 2017 by the VPRO. This populair series gets a follow-up in an online learning programme: ‘Mind of the Universe Online Learning Experience‘, developed and executed by scientists and learning developers of…
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Using an ERC grant to study languages with beans and millet
Japanologist and linguist Martine Robbeets is going to use her newly acquired ERC Consolidator Grant to study the origins and spread of Trans-Eurasian languages, which include Japanese and Turkish. With it, she’s tackling one of the most controversial subjects in language history.