1,520 search results for “marieke biologie” in the Public website
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Karline Janmaat
Faculteit der Sociale Wetenschappen
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Jeroen Hubert
Science
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Niels van der Windt
Science
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Han van Konijnenburg
Science
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Madeline Kavanagh
Science
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Michael Richardson
Science
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Dirk-Jan Kok
Science
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Anugrah Anugrah Aditya Budiarsa
Science
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Molecular Biology for Physics will NOW start on Monday 5 February!
Please note that the course Molecular Biology for Physics will start on Monday 5 February. Please check the schedules for the time and location!
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Why Jesus and Job spoke bad Welsh: The origin and distribution of V2 orders in Middle Welsh
On the 21st of June, Marieke Meelen succesfully defended her PhD-thesis and graduated. LUCL congratulates Marieke on this great result.
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Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Leiden University strengthens its focus on Chemical Biology and Medicinal Chemistry with seven new group leaders
Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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Social Resilience and Security
Social resilience and security has never been more important. Over the last 2 years, the COVID-19 pandemic has created a considerable disturbance to our personal and social lives. As a result, the general population reports more stress, loneliness and decreased quality of life. At the same time, there…
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Terror and the Legitimation of Violence: A Cross-National Analysis on the Relationship between Terrorism and Homicide Rates
This article written by Marieke Liem & Alexander Kamprad investigates the relationship between terrorism and interpersonal violence. They conducted cross-national analyses on the effects of terrorism mortality rates on homicide rates. Results showed that terrorism appears to be robustly and positively…
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?
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Towards an effective biodiversity conservation and governance in the Pontocaspian region
Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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Erik van Kampen publishes in the Journal of Leukocyte Biology: The effects of poor eating habits persist even after diet
New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…
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SAILS Lunch Time Seminar: Marieke van Buchem
Lecture
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Peptide amphiphiles and their use in supramolecular chemistry
Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Child homicide: Media hype, but no indications for copycat effect
Child homicide is a phenomenon that not infrequently leads to shock and societal unrest. However, the precise nature and scope of child homicide in the Netherlands remains unknown.
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When barking dogs bite: A comparison between fatal and non-fatal domestic violence
In this project, we seek to assess, map and understand the risk factors associated with fatal domestic violence.
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Cultures of Collecting: The Leiden Anatomical Collections in Context
The general aim of the project is a description and analysis of the Leiden anatomical collections from a humanities perspective. The project investigates how historical and cultural practices and concerns have shaped anatomical preparations and how exhibitions of the anatomical body have informed cultural…
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Contacts
Main contacts for international activities
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Coaches
These are the coaches connected to the EmPhD project:
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Publications
The Institute of Security and Global Affairs (ISGA) hosts two research journals and publishes the ISGA Reports series. Besides its own publications, researchers at ISGA also publish books or journal articles elsewhere. You can find all these external publications under Research output on the right.
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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25 Years of Lethal Violence
How many men and women die per year at the hands of others? What are the motives behind these killings? Are there as many homicides today as years ago? How can we explain the rise and fall of homicides over time? And: What is the influence of (early) childhood and adolescence on the likelihood to commit…
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Missing the Mark? A Typology of Lethal and Non-Lethal Firearm Violence in the Netherlands
This article describes the phenomenon of firearms violence and the importance of including non-lethal firearms violence in understanding this phenomenon.
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Homicide followed by suicide in the Netherlands: Is there a copycat effect?
Homicide followed by the suicide of the perpetrator often leads to shock and incomprehension. It has been suggested that media reporting on such cases could lead to an imitation effect.
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From Murder to Imprisonment: Mapping the Flow of Homicide Cases
Marieke Liem, Professor Social Resilience and Security at Leiden University, and Katharina Krüsselmann, PhD candidate at Leiden University and Manuel Eisner mapped the flow of homicide cases with the help of a systematic review.
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The intergenerational transmission of an extreme belief systems: Theoretical exploration of a new field of study
With the recent rise and fall of IS, academics and policy makers around the world are expressing concerns about the fate of children of former foreign fighters. Will they follow in their parents’ footsteps? In this paper, Layla van Wieringen, Daan Weggemans and Marieke Liem argue that in light of this…
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Sexual homicide in the Netherlands: a provisional overview
Sexual homicide is a rare phenomenon. Yet, sexual killing is widely reported on in the media. Even though academic research on sexual homicide is conducted abroad, in the Netherlands such research is virtually absent.
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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The tension between nature conservation and economic valuation of ecosystem services
Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters
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Thiosugars: reactivity, methodology and applications
Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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From methanol to medicine – Sustainable microbial production of polyketide antibiotics
Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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Greenifying industrial biotechnology through the creation of synthetic endosymbionts
Is it possible to synthesize industrially relevant compounds in a sustainable manner through the use of light-capturing cyanobacteria?
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Meindert Lamers
Science
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Merijn de Bakker
Science
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Sandra Irmisch
Science
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Lennart Schada von Borzyskowski
Science