Through a lens that examines the intersection of ageing, gender, class, and migration, this project addresses the 'care deficit' in European countries and the employment of migrant women from Latin America to fill this deficit.

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.

Through a lens that examines the intersection of ageing, gender, class, and migration, this project addresses the “care deficit” in European countries and the employment of migrant women from Latin America to fill this deficit.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

Patients share valuable advice and experiences with their peers in online patient discussion groups.

The aim of this project is to develop, evaluate, and multicentre implement a blended form of cardiac rehabilitation that uses a theory-based approach to guide patients to full self-management.

Loneliness and social isolation have become a significant problem in contemporary Japan. The financial burden associated with an ageing population has severely constrained the ability of local authorities to address the problem. As a result, policymakers have sought cost‐effective methods of tackling…

PhD defence

Which criteria do ED patients and therapists evaluate as most relevant for recovery? Do patients and therapists differ in their evaluations? Do eating disorder patients differ from a healthy control group in their scores on the Recovery Scale?

The below schedule gives an overview of the curriculum of the one year fulltime master's programme Health, Ageing and Society for 2024-2025.

This project develops a scientific method to extract clinically relevant new information from patient forum websites that discuss patient experiences concerning e.g. medication, nutrition, co-morbidities, genetic factors etc.

Chronic inflammatory skin diseases such as psoriasis and atopic dermatitis affect both the physical and psychological well-being of millions of patients, leading to persistent symptoms like itchiness and sleeplessness. These conditions often result in decreased productivity and quality of life overall,…

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

The master's specialisation Clinical Neuropsychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

According to a number of British historians, the elderly had a particularly high status in the early Middle Ages. A new book by Leiden cultural historian Thijs Porck sheds a different light on the matter: elderly people had to earn that respect first, and old age was often described in negative terms…

This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.

Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.

This book investigates the effects of brain lesions in the left hemisphere, specifically Broca's area, on the production and perception of vowels, of word tones and of the linguistic use of sentence melody.

The Liverpool care pathway for the dying patient (LCP) is a multidisciplinary tool developed for the dying phase for use in palliative care settings. The literature reports divergent experiences with its application in a nursing home setting related to its implementation and staff competencies. The…

Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

PhD defence

PhD defence

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

This project is a collaboration between Sanquin, LUMC and LIACS. It focuses on the development of meta-modelling methods and tools for the exchange, analysis, and publication of anonymised patient data. Measures are being constructed to evaluate both the level of privacy and the extent to which an anonymized…

We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.

The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.

An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

‘In Hong Kong, the elderly found our popular nature routes boring, so they now cycle our action-packed routes through New York.’ What once started as an assignment for the Master Programme Media Technology, has grown into the international market leader in the field of virtual reality exercises for…

Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…

Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963

The Ministry of the Interior and Kingdom Relations has awarded the Dutch Administrative Law Association (VAR) a start-up grant for one of the projects of the initiative 'Bestuursrecht beter' (better administrative law): a Digital Helpdesk for the Elderly. The grant will enable the VAR to take the first…

How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?

The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…

Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)

PhD research recently completed by pharmacologist Margreke Brill shows that morbidly obese patients should be given a different dosage of the drugs Cefazolin and Midazolam. This could also apply to other drugs such as anti-cancer drugs as well as antibiotics and Margreke Brill is advocating a change…

Navigation Lab Leiden has launched a study on the effects of the navigation training program we have developed, called Wayfinder. Milan van der Kuil is the main researcher on this project and studies how navigation ability can be improved in patients with acquired brain injury.

Menzo Havenga, CEO of Batavia Biosciences on the Leiden Bio Science Park (LBSP), has a favourite hobbyhorse: the Clinical Development Board. The aim of this board is to make sure that high-impact research results in high-value products that will benefit patients.

A group of patients were given a guided tour of the larger than life Rembrandt canvases on University buildings around the Rapenburg canal. This was with the help of students from Present, a volunteer organisation, who pushed their wheelchairs over the bumpy cobblestones. The canvases are on show until…