1,398 search results for “brain function and dysfunction” in the Public website
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Interdisciplinary approach benefits brain research
How do practice and theory reinforce one another in neuroscience? Professor Birte Forstmann’s inaugural lecture on 2 October will be about building interdisciplinary bridges between cognitive neuroscience and cognitive models. Her approach may lead to brain research with fewer side-effects for patie…
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Genetic predisposition to social anxiety disorder measurable in the brain
It was already known that social anxiety disorder often affects more than one person in the same family. But research by PhD student Janna Marie Bas-Hoogendam has now shown that there are genetic brain characteristics that are associated with social anxiety. The PhD ceremony will take place on 14 Ja…
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AI recognizes anxious youth based on their brain structure
A unique multicenter study, including about 3,500 youth between 10 and 25 years old from across the globe, shows that artificial intelligence - specifically machine learning - is able to identify individuals with anxiety disorders based on their unique brain structure.
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Stressed brain, stressed heart?
Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column
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Understanding the brain via language
Professor Jenny Doetjes at Leiden University researches similarities and differences in languages, specifically in the area of numerals and quantifiers. Her research provides insight into language patterns, bu also in the working of the human brain. Inaugural lecture on 26 January.
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Reedijk Symposium 2024: Exploring the Nanomachinery and Substrate Functions of Mycobacterial Type VII Secretion Systems
Lecture
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The distribution of stellar mass in galaxy clusters over cosmic time
Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: Dr. H.Hoekstra
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Music to our ears: How playing an instrument affects the adolescent brain
What impact does growing up in a musical environment or during the COVID-19 pandemic have on the brain development of teenagers? This was the focus of psychologist Lina van Drunen’s PhD research, which studied hundreds of twins. Her findings reveal that practising music slows brain development, presenting…
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Eveline Crone
Faculteit der Sociale Wetenschappen
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Elise Kortink
Faculteit der Sociale Wetenschappen
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Michelle Achterberg receives Award for PhD Thesis on brain development in children
On June 10, Michelle Achterberg received the prize for best dissertation from the Dutch Neurofederation, the network of Dutch neuroscientists, for her thesis 'Like me, ore else...'. Achterberg obtained her doctorate cum laude from the Gravitation Program 'Samen Uniek' of the Leiden Consortium on Individual…
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The importance of friendships in reducing brain responses to stress in adolescents exposed to childhood adversity: a pre-registered systematic
Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.
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People
The Brain and Education lab is a research group in the Institute of Education and Child Studies at Leiden University, the Netherlands. Our group is embedded in the Educational Sciences research program and the Leiden Institute of Brain and Cognition.
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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Vici grant for Bernet Elzinga
Bernet Elzinga (Clinical Psychology) is one of the seven scientists from the Leiden University who has received a Vici grant of 1.5 million euros from NWO. Vici is one of the largest grants for individual scientists in the Netherlands. The funding will enable her to do research for the next five years…
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Cannabis makes you less alert
Regular users of cannabis are less aware of their own mistakes, and they are not good at creative thinking. This is the conclusion drawn by psychologist Mikael Kowal from his research on the effects of cannabis. PhD defence 6 October.
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Fungi of the greening Arctic: compositional and functional shifts in response to climatic changes
Promotor: E.F. Smets Co-promotor: J. Geml
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The mechanical genome : inquiries into the mechanical function of genetic information
The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.
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In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions
Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn
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ARCHITECTURES OF SPEED - reinventing the tools, functions and potentials of speed within rhythmical frames in music
What are the precise identities, possibilities and current practice examples of the various time frames in music and what bearings do they have individually and in combinations on the speed of the music?
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persistence of space: formalizing the polysemy of spatial relations in functional elements
On the 20th of June, Camil Staps successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Camil on this achievement!
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Distinguishing differences in dementia using brain scans
Neuroscientist Anne Hafkemeijer is able to distinguish two different forms of dementia using advanced imaging techniques. This is the first step towards early recognition of dementia in patients on the basis of brain networks. PhD defence 26 May.
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The Mastermind approach to brain research
The brain is a complex organ, and researching medicine to treat brain disorders is equally if not more complex. Elizabeth (Liesbeth) de Lange, Professor of Predictive Pharmacology, calls for a structured approach. ‘In effect, it's like playing Mastermind.’ Inaugural lecture on 22 March.
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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Physics and Engineering Approaches to Biomedicine and Pharmacology
Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.
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Brain changes underlying social anxiety: numbers count!
In a recent mega-analysis, researchers from Leiden University aimed to clarify the contradictory findings of research into social anxiety disorder. They found that to obtain reliable research results having the largest possible sample size is important. Publication in NeuroImage:Clinical.
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Julie Hall
Faculteit der Sociale Wetenschappen
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Rebecca Schaefer
Faculteit der Sociale Wetenschappen
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Hanneke Leegwater
Science
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Dominik Sieh
Faculteit der Sociale Wetenschappen
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Ilse Schuitema
Faculteit der Sociale Wetenschappen
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Kaixuan Pan
Science
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Media attention for the learning adolescent brain
The brains of adolescents react more strongly to receiving rewards. This can lead to risky behaviour, but research in Leiden has shown that it also has a positive purpose: it makes learning easier. The publication of an article on the research findings led to a lot of media attention.
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Cognitive control in context: Neural, functional, and social mechanisms of metacontrol.
To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.
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Predicting drug behaviour in the brain
Does a drug enter into the human brain once administered in the body?
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STRUCTURAL AND EXPRESSIVE FUNCTIONS OF FLEXIBLE TREATMENT OF MUSICAL TIME, IN THE PERFORMANCE OF 19TH CENTURY MUSIC
This research will focus on the relationship between the musical structure and musical time in the performance of 19th century music.
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Het puberende brein
Eveline Crone wrote a new edition of
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Back to the scanner: brain science in times of corona
For their research many neuropsychologists use the brain scanners at the LUMC. At the start of the pandemic, the rules for visiting the hospital became stricter and a large amount of psychology research looked as though it would fall through. Thanks to good protocols the researchers can now pick up…
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Systematic investigations into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
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stratum corneum lipid chain length relates to an impaired skin barrier function in patients with atopic dermatitis
Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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New paper in Experimental Brain Research
Miranda Smit, Ineke van der Ham and colleagues have published a paper in Experimental Brain Research, entitled: Body ownership and the absence of touch: Approaching the rubber hand in- and outside peri-hand space.
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Anxiety traits are visible in the brain
Questionnaires or concentration tasks can be used to screen for anxiety, but so too can EEG recordings – at least indirectly. The frequent mind wandering of anxious people can also be seen on MRI scans. These are just some of the findings of clinical neuropsychologist Dana van Son. PhD defence on 24…
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Increased striatal activity in adolescence benefits learning
Heightened activation of the striatum that adolescents show in response to reward is often associated with risk-taking and negative health consequences. This article in Nature Communications investigates a potential positive side of this heightened activation. It shows that the activity peak in late…
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Inventing anchors? The function of ‘Greek models’ within the process of innovation in Early Roman Drama
To what end and how does Plautus constantly underline the Helleni(sti)c provenance of his art? How does this aspect relate the author’s originality?
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Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
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Function and structure of the eye muscles in myasthenia gravis
PhD defence
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Like me or else...
Nature, nurture and neural mechanisms of social emotion regulation in childhood