496 search results for “renaud systems” in the Public website
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From molecules to planets: Exploring the chemical heritage of solar systems
Walsh
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Fruits of our labour: Work and organisation in the global food system
This is the first special issue of any organisation studies journal on food labour. Why is this a big deal? In this Introduction, we argue that the field should pay much more attention to the agri-food system and the work that goes into producing, distributing and consuming foodstuff. Food is such an…
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Citizenship? Collective Food Procurement in European Cities in "Food, food systems, and agriculture"
Grasseni's contribution to this special feature on food cultures, food systems, and agriculture in Europe builds upon her ongoing project Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale.
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"Entrapment by Consent": the Co-ethnic Brokerage System among Ethnic Yi Labor Migrants in China
Xinrong Ma defended her thesis on 13 February 2018
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SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
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Structural Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
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Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
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WARN-D: developing an early warning system for depression in students
My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?
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Next generation human IPSC-derived reporter systems for image-based analysis of drug adversity
Analysis of drug adversity
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Development of a academic monitoring system for students with learning problems in secondary school
Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years
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Nanomachinery and Substrate Functions of Mycobacterial Type VII Secretion Systems
Lecture
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Understanding membrane fusion at the molecular level using a biomimetic model system
How can the transport of molecules in living cells help to target medicines at exactly the right place?
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Slaves To The System: Researching North Korean Forced Labor in the EU
SLAVES TO THE SYSTEM: Locating Responsibility for Forced Expatriate Labour Practices by the Democratic People’s Republic of Korea (DPRK)
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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policy-making; the contribution of think tanks to policy advisory systems
Think tanks have proliferated in most Western democracies over the past three decades and are often considered to be increasingly important actors in public policy. Still, their precise contribution to public policy remains contested.
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envelope of nuclear magnetic resonance spectroscopy for paramagnetic systems
A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…
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Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems
On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.
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Young suns and infant planets: Probing the origins of solar systems
Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).
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HomininSpace – a large scale simulation system for hominins in the past
HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…
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Bram Klievink: 'The government’s biggest AI challenge is that no system is ever neutral'
Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.
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Polypept(o)ide-based Cylindrical Polymer Brushes as Multifunctional Drug Delivery Systems
The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…
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Development of a universal delivery system for tailor-made cancer vaccines
The potential of liposomal cancer vaccines
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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sentencing: a homicide case flow analysis of the Dutch criminal justice system
Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.
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In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids
This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.
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Systems dermatology of immune-mediated dermatological diseases: cutaneous T-cell lymphoma
The complex pathophysiology of immuno-dermatological disorders is multifactorial, including environmental, skin microbiome, (epi)genetic and immune dysregulation conditions. This project primarily focuses on the orphan disease mycosis fungoides, a subtype of cutaneous T-cell lymphoma. The current pathophysiological…
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glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?
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Cytochrome P450 3A-mediated first-pass and systemic drug metabolism in children
From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.
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Low-Energy Electron Microscopy on Two-Dimensional Systems: Growth, Potentiometry and Band Structure Mapping
Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp
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for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Lessons from the Past for the Financial System of the Future
Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.
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System-level design for efficient execution of CNNs at the edge
A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.
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Measuring sustainability: an elaboration and application of the system of environmental-economic accounting for Indonesia
Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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Schistosoma mansoni Extracellular Vesicles and their Impact on the Immune System
PhD defence
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Improving Side-effects and Quality of Life of Systemic Therapy in Oncology
PhD defence
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Systemic sclerosis: from unravelling the impact of smoking to exploring new views on treatment strategies
PhD defence
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breast cancer cell-intrinsic mechanisms that manipulate the immune system
PhD defence
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PhD: sustainability & circularity-based decision support systems (industrial digital twins)
Science, Institute of Environmental Sciences (CML)
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Revealing the origins of solar systems: examining the formation of proto-planetary disks and binary stars
What is the origin of solar systems?
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and Cosmetic (MAC) Plants in the Utilisation of the Plural Medical System in Pirgos and Praitoria for Community Health Development in Rural Crete
Promotor: Prof.dr. L.J. Slikkerveer
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The phonological systems of the Mbam languages of Cameroon with a focus on vowels and vowel harmony
The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between
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Scientific understanding and provision of an enhanced and robust monitoring system for Responsible Research & Innovation (RRI)
Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational…