If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

In deze opleiding, verzorgd door het Leiden Institute of Chemistry, zoek je naar oplossingen voor complexe, maatschappelijke problemen in volksgezondheid en milieuvraagstukken. We bieden op maat gemaakte, individuele studieprogramma’s, en je hebt de mogelijkheid om onderzoek te doen in het buitenland…

Promotor: Prof.dr.ir. J.G.E.M. Fraaije, Co-promotor: A. Kros

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

In het schoolvak scheikunde is de concept-context benadering ingevoerd. Hans Vogelzang onderzocht of de Scrum-methodologie kan helpen bij het vormgeven van lessen met deze benadering.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Linnartz

By placing food at the centre of investigation, this Minor explores current-day debates on political, environmental, economic and cultural change at both the local and global levels.

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Didactiek

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

Evaluating the environmental consequences of diet changes in the European Union.

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

Description of 20th century changes in the Dutch flora: Description and interpretation (1999 - 2005)

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.

Op de eerste dag van jouw nieuwe baan heb je zweethanden, ben je nerveus en onzeker, maar een paar maanden later zijn die gevoelens al weer verdwenen. Je hebt jouw nieuw rol eigen gemaakt en je bent nu onderdeel van de organisatie. Het proces dat daar naar toe leidt heet

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.

Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

Promotor: J. Schaye

Hoe kunnen docenten in non-STEM-onderwijs klimaatveranderingonderwijs integreren om de kennis, vaardigheden en veerkracht van studenten te verbeteren?

Overkleeft

Promotor: E.F. Smets Co-promotor: J. Geml

De minor Creative Strategies for a Society in Change (CSSC) legt een verbinding tussen het verkrijgen van inzicht in creatieve maakprocessen en het verkennen van maatschappelijke problematieken die kenmerkend zijn voor onze tijd.

‘Gaat het hem lukken?’ Dat is zondermeer de meest gestelde vraag in de Nigeriaanse politiek sinds de opmerkelijke overwinning van Muhammadu Buhari tijdens de presidentiële verkiezingen in 2015.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Does knowledge of environmental performance change farmer's behaviour?

Wat is de institutionele dynamiek van de goedkeuring van wetgeving inzake de interne markt?

Jaroslaw Kantorowicz onderzoekt hoe strategische klimaatprocessen de publieke houding ten aanzien van klimaatbeleid beïnvloeden.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

Deze sociaal-juridische studie richt zich op de implementatie van wetgeving en beleid op het gebied van klimaatverandering in ontwikkelingslanden met een zwakke rechtsstaat en de (onvoorziene) effecten daarvan op de landrechten van kwetsbare bevolkingsgroepen.

The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae