Promotor: F. Arbab

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

Promotor: Prof.dr. D. Bouwmeester

Promotor: Prof.dr. M.L. van Hecke

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

In Sofia Express gaat Jan Paul Hinrichs op zoek naar de literaire geheimen van de Bulgaarse hoofdstad Sofia, een stad waarin detectives, spionage en andere intriges nooit ver weg zijn.

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Promotor: Prof.dr.ir. E. Deprettere

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

The invention of neural networks marks a critical milestone in the pursuit of true artificial intelligence. Despite their impressive performance on various tasks, these networks face limitations in learning efficiently as they are often trained from scratch.

Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Op 17 november 2021 verdedigde Cyril-Igor Grigorieff het proefschrift 'The Regime for International Air Carrier Liability'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof.dr. V. Correia (University Paris Saclay).

Promotor: Prof.dr. B.R. Katzy

How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Op 13 oktober 2021 verdedigde Ross Spence het proefschrift 'Collateral Transactions and Shadow Banking'. Het promotieonderzoek is begeleid door promotoren prof.mr. M. Haentjens en prof.dr. A.M. Pacces (UvA).

In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Promotores: T.H. Oosterkamp, N. de Jonge

This programme aims to make the digitized archival sources of the Kerala and Tamil Nadu Archives more accessible to Indian and international scholars and to the widest possible audience, in particular to the people of Kerala.

Lezing, Studium Generale

Wij doen in het Talentenkracht Centrum Leiden onder andere onderzoek naar exploreren en onderzoekend leren in relatie tot nieuwsgierigheid en de manier waarop jonge kinderen hun eigen gedrag en emoties (leren) reguleren. We willen meer begrijpen over hoe kinderen steeds beter de kapitein van hun eigen…

Een baby past zich in het eerste levensjaar aan aan de taal die hij om zich heen hoort. Daardoor kan een taalachterstand ontstaan, die niet zo makkelijk is op te lossen, stelt hoogleraar Engelse taalkunde Janet Grijzenhout. Oratie 19 maart.

Universiteit Leiden is partner in een nieuw Europees platform van bedrijven en onderzoeksinstellingen dat de basis gaat leggen voor nieuwe geneesmiddelen. Een enorme gemeenschappelijke ‘bibliotheek’ van bestaande en nog te ontwikkelen chemische verbindingen met maximaal 500.000 moleculen zal ongekende…

Universiteit Leiden is partner in een nieuw Europees platform van bedrijven en onderzoeksinstellingen dat de basis gaat leggen voor nieuwe geneesmiddelen. Een enorme gemeenschappelijke ‘bibliotheek’ van bestaande en nog te ontwikkelen chemische verbindingen met maximaal 500.000 moleculen zal ongekende…

Wat werkt in de dagelijkse ondersteuning van verstandelijk beperkte cliënten met een ZZP 6/ 7?

Daniëlla Dam-de Jong is met ingang van 1 februari 2023 benoemd tot hoogleraar op de nieuwe leerstoel International Sustainable Development Law aan het Grotius Centre for International Legal Studies van de Universiteit Leiden. Haar expertise ligt op het gebied van duurzame ontwikkeling, met de nadruk…

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BRAIN Biotech en het Instituut Biologie Leiden (IBL) van Leiden Universiteit gaan samen een Aspergillus schimmelstam verder ontwikkelen. Deze zal in staat zijn meer te produceren en daarmee een biologische circulaire economie stimuleren. De samenwerking is gebaseerd op BRAINs moleculaire hulpmiddel…