Universiteit Leiden biedt bachelor studenten kansen om hun keuzeruimte in te vullen. En daarmee de opleiding te verbreden of te verdiepen.

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Lezing

Veel vraagstukken van onze tijd zijn te complex om vanuit één wetenschapsgebied op te kunnen lossen. De Universiteit Leiden is een brede universiteit waar ongelofelijk veel onderzoeksvelden samenkomen. Daarom zijn we bij uitstek geschikt als broedplaats en beoefenaar van interdisciplinair onderzoek…

De Alumni Nieuwsbrief Pedagogische Wetenschappen verschijnt 2x per jaar.

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Het Instituut Pedagogische Wetenschappen blijft graag met haar alumni in contact en stimuleert de contacten tussen alumni onderling. Het instituut ondersteunt en organiseert diverse diensten en activiteiten voor alumni.

Wat is de betrokkenheid van studenten bij probleemgebaseerd leren (PGO) en casusgebaseerd leren (CBL) in lerarenopleidingen?

Oratie uitgesproken door prof.dr. R.M. van der Rijst bij de aanvaarding van het ambt van hoogleraar Onderwijswetenschappen aan het ICLON van de Universiteit Leiden op vrijdag 13 september 2024

Promovendus Ludwig Hoffmann gaat dankzij een Rubiconbeurs die hij op 11 april won twee jaar naar Harvard University in de VS. Met behulp van theoretische modellen bestudeert hij biologische materialen, bijvoorbeeld tijdens de morfogenese. Dit is het proces waardoor weefsels of organismen hun vorm ontwikkelen.…

1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…

Indigenous Latin American artifacts have attracted the interest of Europeans since the earliest moment of contact between Europeans and the Indigenous peoples of the Americas. The ERC-funded BECACO project uses an innovative multidisciplinary framework to investigate the provenance of ethnographic and…

Nascholing en activiteiten voor natuurkundedocenten op het gebied van sterrenkunde.

In dit jaaroverzicht van 2023 laat Faculteit der Sociale Wetenschappen zien waar we trots op zijn. Aan deze projecten in onderzoek en onderwijs hebben we hard gewerkt.

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.

Cognitieve psychologie is de studie van mentale functies, waaronder aandacht, geheugen, bewustzijn, emotie, taal en actiecontrole. Het doel is om de complexe relaties tussen brein, cognitie en gedrag te begrijpen.

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Announcement of the publication of Vamping the Stage: Female Voices of Asian Modernities, the first book-length study of women, modernity, and popular music in Asia (University of Hawai'i Press, 2017).

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

An interdisciplinary collection of the best international scholarship on Muslim youth.

In this article, Samuels focuses on the active fostering of subjunctivity in processes of narrative worldmaking. Drawing extensively from the narrative of an HIV‐positive woman in Indonesia, she shows that by subjunctively leaving open multiple narrative trajectories and future possibilities, individuals…

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

This thesis focuses on addressing four research problems in designing embedded streaming systems.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Welke uitdagingen bestaan er voor meisjes in het uitoefenen van hun recht op onderwijs en in het bijzonder het krijgen van toegang tot onderwijs?

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.