Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Promotor: Prof.dr. T. Schmidt

An algorithm is discussed to compute the exponential representation of principal units in a finite extension field F of the p-adic rationals.

Promotor: Prof.dr. G.R. de Snoo

Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…

Promotor: J.W. van Holten

Promotores: J.N. Kok, H.J. Hoogeboom

A scenario building web-tool and knowledge package to enable multi-level decision making for the transition to the Circular Economy

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Including modelling as part of software development appears to have various benefits.

Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information⁠. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go⁠.

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Promotor: Prof.dr. M. de Jong

Promotor: I. A. G. Snellen, Co-promotor: M. A. Kenworthy

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

LIACS is a partner in RISE_SMA, an interdisciplinary, international network combining excellent scholars and practitioners to enable vigorous knowledge sharing and to develop solutions for contemporary challenges for Social Media Analytics (SMA).

How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?

Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

Model based approaches, integrating physiological parameters or linking exposure with response, are powerful tools to quantify and evaluate the impact of genetic differences that are reflected as variability of drug exposure and/or clinical response(s). This thesis “Pharmacogenomics in Drug Development: …

Dit gedeelte bevat een overzicht van onze alumni, het loopbaanperspectief naast het doctoraat en "Alumni in beeld", waar we enkele voorbeelden geven van de carrières van sommige van onze alumni na hun promotie.

Promotor: T. H. Oosterkamp

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Promotor: Prof.dr. F. den Hollander, G.Maillard

Promotores: Prof.dr. J.N. Kok, Prof.dr. C.A. Mandemakers, Co-Promotor: G. Bloothooft

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Het Instituut Politieke Wetenschap blijft graag in contact met alumni. Van onze afstudeerders kunnen wij veel leren. En we helpen natuurlijk ook graag een handje om ‘onze’ politicologen in binnen- en buitenland met elkaar te verbinden.

The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotor: R. Gill, Co-promotor: P. Massart

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Alumni-activiteit

Op donderdag 11 juni verdedigt Sabine Witting, promovenda bij Jeugdrecht en eLaw - Centrum voor Recht en Digitale Technologie, haar proefschrift.

Lezing

Hartje zomer en tóch de collegebanken in? Studenten uit de hele wereld komen naar Leiden en Den Haag voor een summer school. De onderwerpen variëren van taalkunde tot internationaal strafrecht en van natuurkunde tot biofarmacie. Docenten en studenten vertellen over leerzame en leuke momenten.

Hieronder vind je de antwoorden op een aantal veelgestelde vragen over toelating tot de klinische specialisaties van de Master Psychologie.

In april 2001 was Nederland het eerste land ter wereld dat het huwelijk openstelde voor paren van gelijk geslacht. Het afstammingsrecht maakt echter nog steeds onderscheid tussen gelijk en verschillend geslacht. Volgens Kees Waaldijk kan dat anders.

Congres/symposium

This book explores the spiritual potential of faith, mysticism and transcendence in answer to the dangers of a mythologised state and the sacro-sanctification of (liberal) democracy and its rule of law.

Promotor: Prof.dr. M. Schilthuizen

Promotor: Prof.dr. M. Ubbink

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia