Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

My work focuses on a class of astronomical objects called protoplanetary disks.

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

Promotor: J.W.M. Frenken

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

Studievoorlichting

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Grensverleggend geschiedenis leren.

Geesteswetenschappen, Centre for Linguistics

Studievoorlichting

Archeologie, World Archaeology

The project falls in the context of the EU Thematic Strategy on the Sustainable Use of Natural Resources (COM(2005)670). The Institute for Environment and Resources (IES) of the Joint Research Centre (JRC) has developed three sets of decoupling indicators. Such indicators require the definition of a…

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

In the first part of this thesis we study the geometry of folding patterns.

Supervisor: P.J.J. Hooykaas

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

Promotor: J. Aarts

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Hydrocarbonylation of alkenes with carboxylic acids in synthesis of carboxylic acid anhydrides is relatively less explored. We herein present a study and optimization of a palladium-catalyzed hydrocarbonylation reaction of alkenes using carboxylic acids as the nucleophile, by which acid anhydrides can…

Promotor: Prof.dr. T. Hankemeier

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Promotor: Prof.dr. E. F. van Dishoeck

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?

HEPGAME is a research project that combines the world’s fastest computer algebra system for High Energy Physics equations, FORM, with insights from artificial intelligence. The name combines High Energy Physics and Games.

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

Promotor: S.M. Verduyn Lunel

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: Prof.dr. M. Danhof

Promotor: Prof.dr. S.F. Portegies Zwart

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

The Institute of Environmental Sciences has carried out and participates in several projects that deal with the analysis of energy systems.