2,524 zoekresultaten voor “discovery of the year” in de Publieke website
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Vooruitkijken naar ‘The Next Ten Years’ bij LDE-jubileumbijeenkomst
De strategische alliantie Leiden-Delft-Erasmus Universities bestaat tien jaar in 2022. Tijdens de jubileumbijeenkomst ‘The Next Ten Years’ in de Faculty Club op 12 april keken de partners terug op wat er bereikt is en werd er vooruitgekeken naar de grote maatschappelijk uitdagingen van de komende tien…
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Chasing cosmic tau neutrinos in the abyss
In this work the reconstruction of a tau neutrino signal in the KM3NeT detector is discussed.
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Boeklancering 'The United Nations Convention on the Rights of the Child’
Het boek 'The United Nations Convention on the Rights of the Child' is het resultaat van internationale wetenschappelijke congres - '25 Years CRC' – dat plaatsvond in november 2014 in Leiden ter gelegenheid van de 25e verjaardag van het VN-Kinderrechtenverdrag.
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Evani Lachmansingh
Wiskunde en Natuurwetenschappen
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The effects of burying beetle social behaviours on interspecific interactions
This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.
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Symposium: The digital reconstruction of the crucifixion of the Lindau master
On 8 July, the symposium 'The digital reconstruction of the crucifixion of the Lindau master (ca. 1425)' will take place at the auditorium of Museum Catharijnecovent, from where it will also be broadcasted online.
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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PhD candidate in the field of biochemistry
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Visual Revolutions in the Middle East
Special Issue in: Visual Anthropology, Volume 29, Issue 3, 2016
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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PhD position in 'Effects of Pollution at the Ecosystem Level'
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity
The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.
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Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
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Twee Leidse finalisten Academische Jaarprijs op Discovery Festival
Universiteit Leiden is op 28 september met twee projecten aanwezig bij het Discovery Festival, een nachtfestival dat draait om de kick die je krijgt als je nieuwe dingen ontdekt. Antibiotica Gezocht! laat de festivalgangers meewerken in het tijdelijke laboratorium en iSPEX: ‘Meet fijnstof met je smartphone’…
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abilities in children with sex chromosome trisomy (XXY, XXX, XYY) aged 1–6 years
Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…
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CfP: Annual Conference of the International Society for the Study of Medieval Theology
On June 26-28, 2024, the Annual Conference of the International Society for the Study of Medieval Theology will take place. The theme this year is "The End: Finiteness, Death and Completion in Medieval Theology". Deadline for paper proposals: 20 December 2023.
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Leiden Law students are looking forward to the lawyer of the future
As Leiden Law students, we are now in the digital age, 'where we believe law and technology should go together.' After all, for us, it is important to look beyond trodden paths of established legal knowledge. The books on law and case law surely will not be sufficient for the lawyer of the future. That…
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Positioning of current Environmental tools & an outlook to the future
Review of new technical decisionsupport systems in the environmental field, and application in water management decission processes.
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Tim Verdoes
Faculteit Rechtsgeleerdheid
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Star formation and aging at cosmic noon: the spectral evolution of galaxies from z=2
Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)
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Spectroscopic characterization of exoplanets: From LOUPE to SINFONI
Over the past years it has been discovered that the population of extra-solar planets is large and diverse.
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The impact of sustainable forest management on plant and bird diversity in East Kalimantan, Indonesia
Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters
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Combining classic and novel tools in the study of Historical Collections of Chinese Materia Medica in the Netherlands
Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…
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On quantum transport in flat-band materials
The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.
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Predicting the future: Predictive control for astronomical adaptive optics
The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.
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Dit was het Leiden Asia Year
Het jaar 2017 was het Leiden Asia Year. Leiden heeft al eeuwenlang banden met en kennis over het continent, en het afgelopen jaar werden daar de spotlights op gezet.
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Lectureship in the Political Economy of Japan (1,0 fte)
Geesteswetenschappen, Institute for Area Studies, Japanese Studies
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Course: Introduction to the Archaeology of the Book
The Summer School History of the Book, organized by the Allard Pierson Museum, introduces a new course in English: Introduction to the Archaeology of the Book, taught by Prof. Malcolm Walsby (2-6 September 2024).
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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PhD: Targeting electron transport chain in Listeria monocytogenes for novel antibiotic development
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Corruption & Integrity in the Netherlands (1945 - present)
Corruption, integrity (or a lack thereof…) and public values are near omnipresent elements in public administration and politics of all times. Cases of corrupt public officials and politicians continuously emerge. Strangely enough, however, it often remains unknown what actually occurred, how something…
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Summer School on the History of the Book
Van 21 augustus tot en met 8 september zijn de workshops en cursus van de jaarlijkse Summer School on the History of the Book van het Allard Pierson en de vakgroep Boekwetenschap. Drie weken lang is er elke werkdag een cursus, workshop of lezing over thema’s die te maken hebben met de geschiedenis van…
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PhD: Modeling the mechanical regulation of plant development and regeneration (1.0 FTE)
Wiskunde en Natuurwetenschappen, Mathematisch Instituut (MI)
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Erik Danen benoemd tot hoogleraar Cancer drug target discovery
Met ingang van 1 april 2018 is Erik Danen benoemd tot hoogleraar Cancer drug target discovery bij het Leiden Academic Centre for Drug Research (LACDR). Zijn vakgebied is celbiologie van kanker, waarin hij zich richt op de achterliggende mechanismen bij uitzaaiingen en resistentie voor behandelingen.
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Postdoctoral Researcher in the project "Contagious Digitalities: Information, Inoculation, Immunity"
Geesteswetenschappen, Centre for the Arts in Society
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Leidse Sterrewacht neemt deel aan International Year of Light 2015
De Leidse Sterrewacht gaat deelnemen aan de activiteiten van het International Year of Light (IYL). Het jaar 2015 is door de Verenigde Naties uitgeroepen tot het International Year of Light and Light-based Technologies. IYL 2015 zal aan de wereld laten zien hoe belangrijk licht en optische technologie…
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The Legal Revolution Against the Accommodation of Religion: The Secular Age v. The Sexular Age
Op 27 juni 2019 verdedigde Barry Bussey zijn proefschrift 'The Legal Revolution Against the Accommodation of Religion: The Secular Age v. The Sexular Age'. Het promotieonderzoek is begeleid door promotor prof. dr. P.B. Cliteur.
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The Sand Motor - Building with Nature to optimise coastal protection and other ecosystem services
How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?
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Freek Vonk krijgt eigen show op Discovery Channel
In het programma Time Warp brengt bioloog Freek Vonk de gevaarlijkste gifslangen ter wereld voor de camera. Zijn doel is niet het tonen alleen, maar vooral het melken van het slangengif ten behoeve van zijn promotieonderzoek. Vrijdag vertelde hij over zijn fascinatie voor slangen in 'De Wereld Draait…
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NMR structural studies of protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal
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Material flow analysis for the C&D waste management systems in the Netherlands, Belgium, Spain and Finland
What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…
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Discovery of Antibiotics and Their Targets in Multidrug-Resistant Bacteria
Promotie
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Race Of The Classics: het Reesgevoel forever
De Race of the Classics is het grootste studentenzeilevenement van Europa. Dit jaar werd de race van 4 t/m 10 april gevaren, met achttien schepen. Daan Kok, tweedejaars Fiscaal recht voer mee in team Leiden op de Tecla, een logger uit 2015. En legt uit hoe het Reesgevoel ontstaat.
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CfP 2023 FIDEM Congress: The Medieval Book Through the Lens of the Librarian (Basel)
The 7th European Congress of Medieval Studies of the Fédération Internationale des Instituts d’Études Médiévales (FIDEM) will be organized by the Department of Arts, Media, and Philosophy of the University of Basel, Switzerland. There is a number of slots for papers (20 minutes) and special sessions…