Het voorgestelde project evalueert hoe de kwetsbaarheid van migrantenmannen en -vrouwen werd geconstrueerd in politieke, publieke en mediadiscoursen, en hoe verschillen in de geconstrueerde kwetsbaarheid van invloed waren op de beslissing om te migreren, het migratieproces en het daaropvolgende vest…

In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

Eén van de gehonoreerde projecten is Bridging art, design and technology through Critical Making van onze hoogleraar Prof. dr. Janneke Wesseling en dr. Florian Cramer (Willem de Kooning Academy).

The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).

Promotor: P.D. Grünwald

In this work, we attempt to answer the question:

This thesis applies data mining in commercial settings in the telecommunications industry.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

De onstuitbare opmars van de N.V. Zuid-Korea

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

Promotor: G.P. van Wezel

Promotores: A.H. Meijer, H.P. Spaink

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Promotor: Prof.dr. M. de Jong

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

In close collaboration with the Center for Medieval Studies (Fordham), Centre for Medieval literature (Odense and York) and Centre for Medieval Studies (York), the University of Ghent organizes an Autumn School for PhD- and MA-students in Medieval Studies (18-22 October 2021). It will be organized in…

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

Promotor: Prof.dr. G.P. van Wezel

Promotor: B.van de Water, Co-promotor: L.S.Price

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.

How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Students Practicing Citizen Journalism

In juli zal een aantal onderzoekers van de Afdeling Jeugdrecht een paper presenteren op de 'Culture, Dispute Resolution and the Modernised Family' conference in Londen, georganiseerd door het International Centre for family law, policy and practice te Londen.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

Sign the petition to save the Bachelor Celtic!

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.

Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'

Comparing the global warming potential (GWP) of the service provided by an iRex Digital Reader to the same service provided by an office printer using a scanning LCA.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue