New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

Kros

Op 29 januari 2019 verdedigde Robbert van Eijk proefschrift 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. Het promotieonderzoek is begeleid door promotor prof. dr. H.J. van den Herik.

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

Promotores: W. Jiskoot, F. Ossendorp

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Tax scandals, like the Panama Papers, the Paradise Papers, and the Pandora Papers, have made taxation a major topic of public debate. Learn more about this in the new minor Tax and Society: Building a Sustainable and Fair Tax System.

Calamus javensis is polymorphic. Morphometry and molecular approach resulted in all names used in the complex are regarded as synonyms of C. javensis except C. tenompokensis, which is retained as a distinct species. One variety is here recognized, C. javensis var. polyphyllus (including C. acuminatu…

Promotor: Prof.dr. J. Kuiper

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Lipsius, Cleveringaplaats 1, 2311 BD, Leiden

This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.

Op 24 september 2020 verdedigde Bernardo Ribeiro de Almeida zijn proefschrift 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.

What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…

Promotor: Prof.dr. M. Ubbink

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

Op 17 december 2018 verdedigde Dejian Kong zijn proefschrift 'Civil Liability for Damage caused by Global Navigation Satellite System'. Het promotieonderzoek is begeleid door promotor prof. dr. P.M.J. Mendes de Leon.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

Het FAIRDOM-consortium is een open initiatief van verschillende partners, waaronder financieringsprogramma's, grote consortia, instituten, kleine groepen en individuen.

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This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

De Belgische verkiezingen zijn voorbij. Nu is het aan de formateur om een kabinet te vormen, maar dat is moeilijk. Fauke Deceuninck, programmaleider van Politiek en Bestuur bij het Centre for Professional Learning, legt bij Spraakmakers uit waarom dat zo is.

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Promotor: Prof.dr. E. Bouwman

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.