10,000 zoekresultaten voor “leiden” in de Publieke website
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The Rome Statute as Evidence of Customary International Law
Op 9 april 2019 verdedigde Yudan Tan haar proefschrift 'The Rome Statute as Evidence of Customary International Law'. Het promotieonderzoek is begeleid door promotor prof. dr. W.A. Schabas.
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Stille wateren hebben diepe gronden
Op 18 januari is de studie ‘Stille wateren hebben diepe gronden – Een analyse van de inkomensverdeling en haar determinanten over de afgelopen veertig jaar’ verschenen. Op deze website kunnen de studie en het achterliggend cijfermateriaal geraadpleegd worden.
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Dynamics of the Oort Cloud and Formation of Interstellar Comets Santiago Torres Rodriguez
The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.
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Militaire Geschiedenis van Nederland - De Tachtigjarige Oorlog (1568-1648)
In juni is het eerste deel van een nieuwe boekenreeks over de militaire geschiedenis van Nederland verschenen: De Tachtigjarige Oorlog (1568-1648). Van Opstand naar geregelde oorlog. Louis Sicking (Instituut voor Geschiedenis, UL) schreef mee aan het boek.
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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Compressed Σ-Protocol Theory
In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.
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Simulating the birth environment of circumstellar discs
Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.
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Complex Patterns in Streams
The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…
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Learning-based Representations of High-dimensional CAE Models for Automotive Design Optimization
In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…
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Transcultural Health Care Utilisation in Serengeti of Tanzania: Towards Applied Ethnoscience in Public Health Management
The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.
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Understanding delinquent development from childhood into early adulthood in early onset offenders
Op 30 september 2021 verdedigde Babette van Hazebroek haar proefschrift 'Understanding delinquent development from childhood into early adulthood in early onset offenders'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.W. de Keijser en prof. dr. A. Popma (VUMC).
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Hartstocht achter de horren: Haagse romans rond 1900
Rond het jaar 1900 maakten zowel de Nederlandse letteren als de stad Den Haag ingrijpende ontwikkelingen door. De romans werden moderner, experimenteler, en vooral vrijmoediger. Deze bundel bespreekt romans van bekende Haagse auteurs als Louis Couperus en Marcellus Emants, maar ook van minder bekende,…
- Aflevering 38: Johan de Witt en het Rampjaar
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The Education and Training of Public Servants
In dit boek geven de auteurs een overzicht van de geschiedenis van ambtenarenopleidingen door cases in Europa, de VS en Australië te analyseren.
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Groepsgeweldplegers en groepsgeweld. De rol van individuele kenmerken
Op 29 september 2020 verdedigde Tom van Ham zijn proefschrift 'Groepsgeweldplegers en groepsgeweld. De rol van individuele kenmerken'. Het promotieonderzoek is begeleid door promotoren prof.dr.mr. A.A.J. Blokland, prof.dr. O.M.J. Adang (RUG) en prof.dr. Th.A.H. Doreleijers (VUMC).
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Metabolomic characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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Mononuclear spin-transition materials based on the bapbpy scaffold
Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Area Studies: Azië & het Midden-Oosten
Het Leiden University Institute for Area Studies (LIAS) wijdt zich aan de bestudering van Azië en het Midden Oosten, vanaf de Oudheid tot het heden.
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Contempt of court
Op 18 december 2019 verdedigde Marianne Lochs haar proefschrift 'Contempt of court'. Het promotieonderzoek is begeleid door promotoren prof.dr. C.P.M. Cleiren en prof.dr. J.H. Crijns.
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The Local Impact of a Global Court: Assessing the Impact of the International Criminal Court in Situation Countries
Op 9 januari 2019 verdedigde Marieke Wierda haar proefschrift 'The Local Impact of a Global Court: Assessing the Impact of the International Criminal Court in Situation Countries'. Het promotieonderzoek is begeleid door promotoren prof. dr. C. Stahn en prof.dr. L.J. van den Herik.
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Positive representations of algebras of continuous functions
If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Uit de schaduw van de wet
Recht is - net als de religie - een vorm van kunst, aldus de auteur.
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Cognitive enhancement: Toward the integration of theory and practice
Cognitive enhancement is het gebruik van elke methode of techniek met als doel het verbeteren van cognitieve prestaties.
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Deepening the uncertainty dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
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Winnaars en verliezers
In september is de tweede herziene druk verschenen van Leo Lucassen en Jan Lucassen, Winnaars en verliezers. Een nuchtere balans van vijf eeuwen immigratie (Bert Bakker/Prometheus). Deze editie bevat een nawoord waarin de auteurs ingaan op de relatie tussen de aanslagen van Anders Breivik in Noorwegen…
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste
Op 24 september 2020 verdedigde Bernardo Ribeiro de Almeida zijn proefschrift 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.
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Structure dependence of molecular reactions on surfaces
The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.
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Combining monitoring with run-time assertion checking
Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
- Niederländisch 1 für Deutschsprachige
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Van voetbalvrouwen tot vrouwenvoetbal
Wat is de maatschappelijke impact (sociale betekenis) van vrouwenvoetbal in Nederland?
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Taalkundeolympiade
Hou je van taal en logica en zit je in 4, 5 of 6 vwo? Dan is de Taalkundeolympiade iets voor jou!
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Bakti and Sayan traditions among the Tenggerese people in East Java: the role of indigenous institutions in integrated elderly care development
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…
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Duurzaam bouwen
Fase 2A van het Gorlaeus Gebouw wordt, net als fase 1, duurzaam gebouwd.
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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Adjudicating Attacks Targeting Culture
Op 27 mei 2021 verdedigde Hirad Abtahi zijn proefschrift 'Adjudicating Attacks Targeting Culture'. Het promotieonderzoek is begeleid door promotor prof.dr. C. Stahn.
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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General plant strategies and functions in wetlands: Global trait-based analyses
Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.