The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.

De politicologen Joop van Holsteyn en Tom Louwerse (Universiteit Leiden) zien dat referenda in Nederland de Euroscepsis een stem geven. Maar van een ‘Nexit’ is nog lang geen sprake.

Op 1 juni 2022 verdedigde Tom Herrenberg het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. P.B. Cliteur en prof.dr. B.R. Rijpkema.

Informele kennismaking voor de empirische-juridische nieuwkomers en zoekenden.

Marietje Beemsterboer verdedigde haar proefschrift op 12 juni 2018.

Martijn Junte verdedigde zijn proefschrift op 21 september 2017

Rekenen en onderzoekend leren voor groep 5, 6, 7 basisschool.

This thesis discusses the discovery potential of Intensity Frontier experiments.

Op welke manier kunnen docenten de betrokkenheid van studenten ondersteunen en vergroten in de context van blended learning?

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Hier vindt u links naar diverse pagina's die scholieren ondersteunen en stimuleren bij het maken van hun profielwerkstuk.

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

Vakantievierders, dagjesmensen en toeristen konden universitaire rondleidingen boeken met een student als gids.

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

Congres/symposium

Het Campusplein, officieel Rosalind Franklinplein, wordt een groene ontmoetingsplek voor studenten, medewerkers en inwoners van de stad. Hier komen de universiteit, het bedrijfsleven en de stad Leiden samen.

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov

Promotor: Prof. dr. A.G.G.M. Tielens

Maak kennis met de specialisten van het Selectief Mutisme Expertise Team

In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

Het Central Innovation District (CID) vormt het economisch hart van de stad Den Haag .

Als wetenschappelijke partner biedt het Sport Data Center (sport)organisaties een aantal diensten.

Didactiek

D1.2 reports on the findings of an analysis of framework conditions relevant in the context of the data economy from a legal, a socio-economic and a technological perspective. The analysis is a key foundation for the creation of an initial, heuristic model of the European data economy. The deliverable…

Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Het onderzoek binnen COI@Leiden is geclusterd rond twee thema's: duurzame rechtspraak en de rechtszaal als maatschappelijke arena. Lees meer over elk van deze projecten door op de onderstaande links te klikken.

The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.

Er worden verschillende activiteiten georganiseerd in het kader van het gastschrijverschap. Vast onderdeel is de Albert Verweylezing, die Giphart op donderdagavond 21 november 2024 zal houden. Op 11 september wordt Giphart geïnterviewd door Sander Bax en Rick Honings.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

Promotores:Th.J.C. van Berkel, M. van Eck

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

Promotores: C.A.J. Knibbe, D. Tibboel, Co-Promotor: P. Bruins

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda

This thesis focuses on the study of transient and variable radio sources in the universe.

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

Gorlaeus Gebouw, Einsteinweg 55, 2333 CC, Leiden

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

Dissociative chemisorption is an important reaction step in many catalytic reactions.