2,829 zoekresultaten voor “specifieke for a” in de Publieke website
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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Novel formulations and delivery strategies for inactivated polio vaccines : new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
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Nu beschikbaar: Open Science - A Practical Guide for Early-Career Researchers
Dit is een praktische handleiding gericht op promovendi, Research Master studenten en early-career researchers uit alle vakgebieden. De instructies in de gids zijn bedoeld als inspiratie voor jonge onderzoekers en als hulp om Open Science te beoefenen door hun onderzoek zo open als mogelijk te delen…
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Digital tools for sign language research: towards recognition and comparison of lexical signs
Op 9 april promoveert Manolis Fragkiadakis. Het Leiden University Centre for Linguistics feliciteert Manolis!
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The implementation of international law in the national legal order: A legislative perspective
Op 5 juni 2018 verdedigde Emile Beenakker zijn proefschrift getiteld ‘The implementation of international law in the national legal order: A legislative perspective’. Het promotieonderzoek is begeleid door promotor professor W.J.M. Voermans.
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The writing culture of ancient Dadan; a description and quantitative analysis of linguistics variation
Fokelien Kootstra verdedigde haar proefschrift op 23 april 2019
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dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Giant barrel sponges in diverse habitats: a story about the metabolome
Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.
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Modelling the dynamics of the innovation process: a data-driven agent-based approach
Promotor: Prof.dr. B.R. Katzy
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Chemical functionalization of the graphene surface for electrical and electrochemical sensing application
Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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A culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
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Effectiveness of audience segmentation in instructional risk communication: A systematic literature review
This article provides a list of the concepts and key elements that should be considered when creating effective communication messages.
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PEERS
In dit project wordt gekeken naar kinderen en hun relaties met leeftijdsgenoten. We willen daarbij graag meer te weten komen over het welzijn van kinderen en hoe dit gelinkt is aan onderwerpen zoals vriendschappen, angst en sociale vaardigheden. Door naar deze onderwerpen en hun samenspel te kijken,…
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Formulation of influenza T cell peptides: In search of a universal influenza vaccine
Promotores: Prof.dr. G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij
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A fixed point approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Dutch Post-war Fiction Film through a Lens of Psychoanalysis
Deze week verscheen 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' van Peter Verstraten bij Amsterdam University Press, het vervolg op Humour and Irony in Dutch Post-war Fiction Film uit 2016. Elk hoofdstuk in zijn 482 pagina's tellende nieuwe studie begint met een titel van Fons Rademakers…
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Molecular inheritance from cloud to disk: a story of complex organics and accretion shocks
Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.
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Triple bottom line approach for risk-benefit analysis of genetically modified crops
Description of Triple bottom line approach for risk-benefit analysis of genetically modified crops.
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken
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Environmental assessment and guidance for the future offshore wind energy development
This thesis aims to address offshore wind energy (OWE)-related environmental impacts.
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Model-assisted robust optimization for continuous black-box problems
Uncertainty and noise are frequently-encountered obstacles in real-world applications of numerical optimization. The practice of optimization that deals with uncertainties and noise is commonly referred to as robust optimization.
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Ruthenium- and cobalt-based artificial metalloenzymes for photocatalytic water oxidation in artificial photosynthesis
Producing green energy has become the main goal in our society in the search of reducing or eliminating the carbon emission from fossil fuels.
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Multi-Objective Bayesian Global Optimization for Continuous Problems and Applications
A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
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A well-established harmony in chaos: from isolated galaxies to galaxy clusters
The origin and evolution of galaxies are closely linked to many different physical phenomena.
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A fresh view on carbon radio recombination lines powered by LOFAR
The Low Frequency Array enables studies of low-frequency carbon radio recombination lines with unprecedented sensitivity, spectral and spatial resolution.
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Sheltering 10 billion people in a warming and resource-scarce world: challenges and opportunities
Sheltering is an immediate human need and determines well-being andhealth.
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Theory of Mind in Language, Minds and Machines: a Multidisciplinary Approach
Promotie
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Van Vonno, Achieving Party Unity: A Sequential Approach to Why MPs Act in Concert (dissertatie)
Cynthia van Vonno, politicoloog aan de Universiteit Leiden, verklaart in haar proefschrift waarom individuele parlementariers meestemmen met hun fractie.
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco
Dr. Joris Larik, universitair docent vergelijkend, EU- en internationaal recht bij LUC The Hague, is coauteur van het rapport 'UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco'.
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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Stevig en snel ingrijpen in drie specifieke gebieden biedt ademruimte in stikstofcrisis
Een nieuw kabinet moet op korte termijn in drie specifieke regio’s snelle en vergaande maatregelen nemen om de stikstofuitstoot tegen te gaan. Zo komt er ruimte voor een lange-termijn-aanpak om andere urgente problemen aan te pakken en de knoop aan verplichtingen die de staat heeft te ontwarren. Dit…
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A Manifesto for Investigating the Impacts of Object Flows on Past Societies: Objectscapes
World history is often framed in terms of flows of people and migration: humans coming ‘out of Africa’, the spread of farmers in the Holocene, Phoenician and Greek diasporas over the ancient Mediterranean, the colonization of the world by Europeans from the 16th century onwards. Together with his Exeter…
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Plan B for particle physics: finding long lived particles at CERN
This thesis discusses the discovery potential of Intensity Frontier experiments.