1,873 zoekresultaten voor “kees from” in de Publieke website
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Progressive Indexes
Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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spFRET studies of nucleosome dynamics modulated by histone modifications, histone variants and neighboring nucleosomes
Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
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Measuring gold molecular gas across cosmic time
Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…
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Tuesday Talks
De maandelijkse dosis onderzoeksinspiratie van Leiden Science, van onze medewerkers, voor onze medewerkers en alle andere nieuwsgierigen. Op dinsdag 3 september geeft Ionica Smeets, hoogleraar wetenschapscommunicatie, een interessante lezing!
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Effective Protection of Fundamental Rights in a pluralist world
Welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit op het terrein van de rechten van de mens voor de effectieve bescherming van die rechten in een wereld die gekenmerkt wordt door pluralisme?
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Goudswaard: 'Goede zaak dat professionelere pensioenfondsen overblijven'
Kleine pensioenfondsen worden gedwongen te stoppen vanwege de strengere eisen. Regels worden complexer en pensioenbestuurders moeten aan steeds strengere eisen voldoen.
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Reasoning about object-oriented programs: from classes to interfaces
Promotie
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Hiltje Cleveringa ontvangt eerste biografie over haar vader
Ontroerd nam Hiltje Cleveringa op 16 januari het eerste exemplaar in ontvangst van de biografie van haar vader Rudolph Cleveringa. Met enkele cliffhangers in zijn toespraak – onder ander over Churchill – moedigde biograaf Kees Schuyt het publiek aan zijn boek ook daadwerkelijk te gaan lezen.
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Studie-informatie alle vakken
Onderstaand een overzicht van alle vakken die door de afdeling Economie worden verzorgd.
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Research Seminar Series
For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent
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Role of near-surface environment in tuning electrochemical CO2 reduction reaction and H2 evolution reaction
This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…
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Florian Schneider
Gamic Learning in East Asian Studies - Wat kunnen spellen ons vertellen over de manier waarop mensen leren?
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Noisy Patterns: Bridging the gap between stochastics and dynamics
In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Gravitational waves through the cosmic web
The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.
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Anyonic, cosmic, and chaotic: three faces of Majorana fermions
In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…
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EXIOBASE
EXIOBASE is a global, detailed Multi-regional Environmentally Extended Supply and Use / Input Output (MR EE SUT/IOT) database. It was developed by harmonizing and detailing SUT for a large number of countries, estimating emissions and resource extractions by industry, linking the country EE SUT via…
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Assessing the link between television consumption and the attitudes toward people living with HIV/AIDS in Chile
We analyse the link between media consumption and the attitudes toward people living with HIV/AIDS in Chile. We used data from a sample of 1000 people, obtained in the 2011 wave of the World Values Survey (WVS). We use a logistic binary regression model by maximum likelihood. Our results suggest that…
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Silicon pore optics for high-energy optical systems
This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.
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Jaarverslag CML 2013 - 2014 (English)
In 2013-2014, CML published over 100 papers, contributed to various international sustainability debates, renovated our building and educated thousands of students from all over the world through our MOOC. These accomplishments and many more are highlighted in this booklet, CML wish you a pleasant…
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The physics of nanowire superconducting single-photon detectors
Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)
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Knowledge extraction in the quantum random-oracle model
The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.
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Jaarverslag CML 2015 (English)
In 2015, CML published over 70 papers, contributed to the United Nations conference on climate change in Paris, won awards and advised the Dutch government on the safe use of pesticides. CML awarded 11 PhDs and taught students from all over the world how to contribute to sustainability. We wish you…
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Prediction Sets via Parametric and Nonparametric Bayes: with Applications in Pharmaceutical Industry
This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.
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Topological aspects of rational points on K3 surfaces
Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
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Alumni
Sinds 2009 behaalden 84 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.
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Obesity and Metabolic Syndrome: From Clinical to Public Health Perspectives. Results from population-based studies of the Dutch and the Indonesian
Promotie
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Ethan Mark
Grensverleggend geschiedenis leren.
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Pesticides Atlas, Pilot Study
Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.
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Policy Review on Decoupling
Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?
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Monitoring and detection of nanomaterials in biological media.
How do nanoparticles bioaccumulate and biodistribute in organisms?
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Postdoctoral Researcher in the project "Contagious Digitalities: Information, Inoculation, Immunity"
Geesteswetenschappen, Centre for the Arts in Society
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Staging cerebral amyloid angiopathy: From marker to model
Promotie
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PhD: Targeting electron transport chain in Listeria monocytogenes for novel antibiotic development
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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PhD student in Biochemistry, Structure and Function of Archaeal Chromatin
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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NWO-subsidie voor onderzoek naar rekenen in het basisonderwijs
Psycholoog Kees van Putten (Methoden en Technieken) doet onderzoek naar het rekenpeil van basisschoolleerlingen. Van Putten wil vooral weten met welke aanpak van de leerkracht ook zwakke rekenaars beter leren rekenen. Hij ontvangt een subsidie van € 300.000 voor dit project dat wordt uitgevoerd in samenwerking…
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Uniek nieuwsfeitje – 100 gemeenschappelijke publicaties!
Sinds 1993 doen de economen Kees Goudswaard en Koen Caminada veel gezamenlijk onderzoek op het terrein van sociale zekerheid, verdelingsvraagstukken en pensioenen. Vandaag bereikten zij een mijlpaal – hun 100ste gemeenschappelijke publicatie.
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Jean Monnet Chair of Moritz Jesse
Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.
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Postdoctoral Researcher in the project "Do we owe anything to ourselves?"
Geesteswetenschappen, Instituut voor Wijsbegeerte