In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

This thesis utilises the exceptional sensitivity and resolution of LOFAR to explore the low-frequency Universe, while simultaneously advancing the telescope's capabilities to enable new scientific discovery.

Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.

The investigation into the bidirectional communication between the gut and its host is a rapidly growing area of research, attracting considerable attention for its potential to provide crucial insights into health and disease.

Het onderzoek van de Intelligence and Security Studies Group naar inlichtingen en veiligheid draagt bij aan academische kennis, voedt de publieke discussie, ondersteunt ons onderwijs en de ontwikkeling van professionele praktijk.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

De Faculty of Governance and Global Affairs

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

Binnen de sectie Gezondheids-, Medische en Neuropsychologie wordt onderwijs verzorgd en onderzoek verricht op verwante deelgebieden van de psychologie: Gezondheids-, Medische en Neuropsychologie.

Visualizing the internal structure is a crucial step in acquiring knowledge about the origin, state, and composition of cultural heritage artifacts. Among the most powerful techniques for exposing the interior of cultural heritage objects is computed tomography (CT), a technique that computationally…

Het beste van Leiden en Delft komt samen in de bachelor opleiding Life Science & Technology. Benieuwd naar het programma? Bekijk de video.

An assessment approach that tailors to children’s instructional needs

Promotores: H. Schiessel, G.T. Barkema

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Promotor: S.M. Verduyn Lunel

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

Veel mensen binnen de Universiteit Leiden zijn verbonden aan Academia in Motion.

This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.

Doordat markten in toenemende mate zijn geïnternationaliseerd, zijn (sub-)nationale toezichthouders ook steeds vaker internationaal actief. Binnen vormen van internationale netwerksamenwerking wisselen deze toezichthouders onderling informatie uit en onderhandelen ze over internationale standaarden…

My work focuses on a class of astronomical objects called protoplanetary disks.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Een wetenschappelijk onderzoek naar de versterking van de verantwoordelijkheid van gecontroleerde entiteiten zelf rondom de accountantscontrole en de jaarverslaggeving.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Mapping the neural mechanisms underlying social motivations of adolescents and adults

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Promotor: A. Achúcarro Co-promotor: A. Boyarsky

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).