The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

The invention of neural networks marks a critical milestone in the pursuit of true artificial intelligence. Despite their impressive performance on various tasks, these networks face limitations in learning efficiently as they are often trained from scratch.

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

This dissertation consists of two parts, each of which considers a different research area related to random interval maps. In the first part we are interested in random interval maps that are critically intermittent.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet

The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

MCS bestaat uit vijf medewerkers, die allen sterke banden hebben met de ‘museums and collections’ opleiding bij de faculteit geesteswetenschappen en ‘heritage and museums’ bij de faculteit archeologie.

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

Studievoorlichting

Hoe kan de methode om de gecombineerde effecten van metaal-gebaseerde chemische stoffetn te bepalen worden verbeterd?

A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

This thesis focuses on addressing four research problems in designing embedded streaming systems.

LIACS is a partner in the EU Erasmus+ Curriculum Development for the Asian education system. The knowledge available in the field of Data Science and Artificial Intelligence education will be shared and adapted for the Asian market.

Promotor: Richard D. Gill

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

Je wordt alleen toegelaten tot de master Geneeskunde in Leiden als je in het bezit bent van een bachelordiploma Geneeskunde.

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

De Academy of Creative and Performing Arts (ACPA) verzorgt artistiek onderzoek en onderwijs in de kunsten.

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Per jaar krijgen in Nederland meer dan vierduizend vrouwen de diagnose gynaecologische kanker. Rinske Bakker onderzocht hoe vrouwen die daar behoefte aan hebben na behandeling hun seksuele relatie weer op kunnen pakken.

Eén van de gehonoreerde projecten is Bridging art, design and technology through Critical Making van onze hoogleraar Prof. dr. Janneke Wesseling en dr. Florian Cramer (Willem de Kooning Academy).

Onderzoekers van de Universiteit Leiden werken samen met Ouwehands Dierenpark om beter inzicht te krijgen in de emoties en intelligentie van orang-oetans. Het publiek van de dierentuin kan nu zien hoe orang-oetans zich uitleven op computer-touchscreens.

Grensverleggend geschiedenis leren.

Students Practicing Citizen Journalism

Aan de hand van de karakteristieke aspecten van een beeld kunnen bepaalde computers ons vertellen wat het beeld laat zien. Ze kunnen dit leren op dezelfde manier als jonge kinderen beelden kunnen leren herkennen. Het verder verbeteren van deze technieken opent de weg naar een hele reeks nieuwe toepassingen.…