1,421 zoekresultaten voor “computational modellen” in de Publieke website
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Data Science
Het merendeel van de wetenschappers, van archeologen tot zoölogen, verzamelt enorme hoeveelheden gegevens. Hun databanken bevatten grote hoeveelheden informatie die voor de mens moeilijk te filteren zijn. Met een stevige basis in de statistiek en de computerwetenschappen kunnen we algoritmes ontwikkelen…
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Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.
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Systematic investigations into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
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Data-driven donation strategies: understanding and predicting blood donor deferral
The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Random walks and the contact process
Promotores: W. Th. F. den Hollander, M.O. Heydenreich
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
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Samenwerkend leren bij lerarenopeldingen
Het ontwikkelen, gebruiken en evalueren van groepsopdrachten in het hoger onderwijs.
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
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Explorations of Water Oxidation Catalysis in Explicit Solvent
In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.
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Adsorption and catalysis on Pt and Pd monolayer-modified Pt single crystal electrodes
The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.
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Designing Ships using Constrained Multi-Objective Efficient Global Optimization
A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.
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Interactive scalable condensation of reverse engineered UML class diagrams for software comprehension
Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)
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Gibbs-non-Gibbs transitions and vector-valued integration
Promotor: W. T. F. den Hollander, F. H. J. Redig
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Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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Playing dice with the Universe
The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Automated machine learning for dynamic energy management using time-series data
Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…
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ReCiPe
The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink
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Foam rheology near the jamming transition
Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Simon Portegies Zwart
Wiskunde en Natuurwetenschappen
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Marco Visser
Wiskunde en Natuurwetenschappen
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Evert van Nieuwenburg
Wiskunde en Natuurwetenschappen
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Waves and Patterns in Discrete Media: Bridging the Gaps
What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body
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Plan B for particle physics: finding long lived particles at CERN
This thesis discusses the discovery potential of Intensity Frontier experiments.
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Prediction Sets via Parametric and Nonparametric Bayes: with Applications in Pharmaceutical Industry
This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.
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Metals in LCIA
A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.
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Mosselen organiseren zich als moleculen in materiaal
Mosselen in mosselbedden vormen een patroon dat lijkt op de organisatie van moleculen en atomen in materialen als brons, staal of rubber. Dit gedrag kan dan ook worden beschreven met hetzelfde wiskundige model.
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Dynamical Gibbs-non-Gibbs transitions and Brownian percolation
Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.
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Probing the properties of dark matter particles with astrophysical observations
It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Nonparametric Bayesian Methods in Robotic Vision
In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Sterile neutrinos in the early Universe
Promotor: A. Achúcarro, Co-promotor: A. Boyarsky
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
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Bridging the gap between physics and chemistry in early stages of star formation
A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.
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Licht op het oudste scheepsmodel
In het Scheepvaartmuseum van Amsterdam bevindt zich een getuigd model van een driemasterschip uit de tweede helft van de zestiende eeuw: het oudste scheepsmodel in de museumcollectie. Historicus Louis Sicking deed in opdracht van het museum onderzoek naar dit bijzondere object.
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Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.
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Development of an in vitro vascular network using zebrafish embryonic cells
One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.