1,032 zoekresultaten voor “brain function and dysfunction” in de Publieke website
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2010
LIBC PUBLIEKSDAG 'SLEEP(LESS) IN LEIDEN' (In Dutch)
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Call for Papers and Panels: Global Transformations and Governance Challenges (GTGC) Conferentie 2023
Van 7-9 juni 2023 organiseert Global Transformations and Governance Challenges (GTGC) haar tweede internationale conferentie in Den Haag. Deadline voor inzendingen: 15 februari 2023.
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Call for Papers and Panels: Global Transformations and Governance Challenges (GTGC) Conferentie 2022
Van 8-10 juni 2022 organiseert Global Transformations and Governance Challenges (GTGC) haar eerste internationale conferentie in Den Haag. Deadline voor inzendingen: 22 april 2022.
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Gehandicapten bewegen in toekomst dankzij technologie Minority Report
Vanaf vandaag is Microsoft Kinect te koop. Met de camera voor de Xbox 360 is het mogelijk om games te spelen zonder controller. Volgens Fons Verbeek van het Leidse Institute of Advanced Computer Science zou Kinect daarom wel eens het begin kunnen zijn van een hele nieuwe generatie computer interfaces.…
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Tien jaar Life Science and Technology
Op 9 september 2009 viert de opleiding Life Science and Technology (LS&T) haar tienjarig bestaan.
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Mattijs Numans
Faculteit Geneeskunde
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Antonius Johannes Rabelink
Faculteit Geneeskunde
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Inge Ligtvoet
Faculteit der Geesteswetenschappen
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Liwen Meng
Faculteit der Sociale Wetenschappen
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Peter van der Zwan
Faculteit Rechtsgeleerdheid
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Peter de Knijff
Faculteit Geneeskunde
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
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Tommy van Avermaete
Universitaire Bibliotheken Leiden
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Alies Jansen
Faculteit der Geesteswetenschappen
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Abdourahamane Idrissa Abdoulaye
Afrika-Studiecentrum
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Susan van den Brink
Wiskunde en Natuurwetenschappen
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Een geluid van mensen met locked-in-syndroom
Mensen met beperkingen vinden dat hun expertise over bijvoorbeeld het locked-in-syndroom onvoldoende wordt gehoord. 'Zonde', stelt psycholoog Femke Nijboer, 'want zo missen zorg en industrie een kans op betere producten.'
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Topwetenschappers vertalen hersenonderzoek naar onderwijs
Eveline Crone is lang niet de enige professor puberbrein op het internationale FLUX-congres. Leiden was vier dagen lang het centrum van onderzoek naar hersenontwikkeling. Opvoeders en beleidsmakers ontmoetten wetenschappers tijdens het publiekssymposium op 18 september.
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Using cryo-EM methods to uncover structure and function of bacteriophages
Promotie
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Novel Imaging Insights into Cardiac Remodeling, Myocardial Function and Risk Stratification in Cardiovascular Disease
Promotie
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Beyond Perfusion: Measuring Water Transport Across Brain Barriers with Arterial Spin Labeling MRI
Promotie
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Eduard Fosch Villaronga
Faculteit Rechtsgeleerdheid
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Metals in LCIA
A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.
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Identification and characterization of viral Xrn1-resistant RNAs
Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.
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against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Algebraic techniques for low communication secure protocols
Promotor: R. Cramer
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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Opportunity and Problem in Context (OPiC). A framework for environmental management in developing countries
Promotor: W.T. de Groot
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Inducing spin triplet superconductivity in a ferromagnet
Promotor: J. Aarts
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.
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On the 16-rank of class groups of quadratic number fields
Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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The stochastic geometry of non-Gaussian fields
Promotor: V. Vitelli, Co-promotor: J. Paulose
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Metabolomics assisted with stable-isotope labeling: exploring neuronal metabolism related to Parkinson’s disease
The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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bacterial cell wall components: teichoic acids, capsular polysaccharides and phosphatidyl glycerol analogues
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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bad? The mutant! Characterization of cancer-related somatic mutations and identification of a selectivity hotspot in adenosine receptor
G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.
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Strings and AdS/CFT at finite density
Promotores: J. Zaanen, A. Parnachev
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Shaping Massive Galaxies: the structural evolution of galaxies across
Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Adaptive responses to environmental changes in Lake Victoria cichlids
Promotor: M.K. Richardson, Co-Promotor: F. Witte
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interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Flexing the Slot Regime
Op 16 december 2021 verdedigde Lisanne van Houten het proefschrift 'Flexing the Slot Regime'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof. L. Pierallini (Luiss University Of Rome).
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml