1,633 zoekresultaten voor “mathematical and statistical modelling” in de Publieke website
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Cornelis Hokke
Faculteit Geneeskunde
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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Advances in Survival Analysis and Optimal Scaling Methods
This thesis is based on five papers on several topics.
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Diophantine equations in positive characteristic
In this thesis three different topics in number theory are studied.
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Leiden University wins best position paper at the 2019 Model ICAO
The 2019 Model ICAO took place from 21-24 May at the ICAO headquarters in Montreal.
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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Non-Abelian metamaterials: emergent computing and memory
In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.
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MULTIPLY - MULTIscale SENTINEL land surface information retrieval Platform
Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.
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the C&D waste management systems in the Netherlands, Belgium, Spain and Finland
What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…
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Tomer Fishman
Wiskunde en Natuurwetenschappen
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Shiza Aslam
Wiskunde en Natuurwetenschappen
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maximising approaches to evaluate the trade-offs involved in the evergreen and deciduous conundrum
Which traits and/or trade-offs determine benefits of being deciduous or evergreen?
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Vincent Croft-
Wiskunde en Natuurwetenschappen
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Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
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arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Enumerative arithmetic
This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.
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Spectroscopy of two-field inflation
This thesis is about cosmological inflation and its relation to observations.
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Actors at work
Promotor: F.S. de Boer Co-promotor: P. T. de Gouw
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NMR studies of protein-small molecule and protein-peptide interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Calculated Moves: Generating Air Combat Behaviour
By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.
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Anyonic, cosmic, and chaotic: three faces of Majorana fermions
In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…
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IDREEM - Increasing industrial resource efficiency in European mariculture
What are the environmental trade-offs for SMEs considering moving from monoculture aquaculture practice towards IMTA? What are the environmental trade-offs comparing IMTA species with their conventional monoculture alternatives?
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Studieprogramma
Tijdens deze studie volg je colleges, oefen je met wiskundige afleidingen en voer je experimenten uit. Hierdoor bouw je een stevige basis in verschillende vakgebieden, zoals natuurkunde en wiskunde.
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representation in Multi-sensor Earth Observation Products through phenology and trait-based priors
What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Bayesian learning: challenges, limitations and pragmatics
This dissertation is about Bayesian learning from data. How can humans and computers learn from data?
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The power of one qubit in quantum simulation algorithms
Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…
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Quantitative Super-Resolution Microscopy
Promotor: T. Schmidt
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Quantum computation with Majorana zero modes in superconducting circuits
Promotor: Prof.dr. C.W.J. Beenakker
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Imperfect information variants of combinatorial games
Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go.
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Het belang van vriendschappen voor het verminderen van stressreacties bij jonge mensen die een ingrijpende ervaring hebben opgedaan tijdens hun
Van alle kinderen en adolescenten die wereldwijd opgroeien, maakt ongeveer de helft ten minste één ingrijpende gebeurtenis mee in de jeugd. Deze ingrijpende jeugdervaring is een van de belangrijkste voorspellers voor psychopathologie in het latere leven.
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Blowup in the complex Ginzburg-Landau equation
Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer
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Mirko Forastiere
Wiskunde en Natuurwetenschappen
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Sebastiaan Deetman
Wiskunde en Natuurwetenschappen
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Analysis of sarcoma and non-sarcoma clinical data with statistical methods and machine learning techniques
Promotie
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G-zips and Ekedahl-Oort strata for Hodge type Shimura varieties
Promotores: S.J. Edixhoven, F. Andreatta
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Compiling and Refining Environmental and Economic Accounts (CREAA)
CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.
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Paul Wouters
Faculteit der Sociale Wetenschappen
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Jian Wang
Faculteit der Sociale Wetenschappen
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Vincent Chang
Faculteit der Geesteswetenschappen
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Frank Baas
Faculteit Geneeskunde
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Wiskundige app voorspelt overlevingskansen kankerpatiënten
Een nieuwe app kan de overlevingskansen van patiënten met wekedelentumoren voorspellen. De app en het onderliggende wiskundige model zijn ontwikkeld door wetenschappers van het Mathematisch Instituut en LUMC.
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Ewout Steyerberg
Faculteit Geneeskunde