Kunst en vrije tijd, Kunst en vrije tijd

In het programma Time Warp brengt bioloog Freek Vonk de gevaarlijkste gifslangen ter wereld voor de camera. Zijn doel is niet het tonen alleen, maar vooral het melken van het slangengif ten behoeve van zijn promotieonderzoek. Vrijdag vertelde hij over zijn fascinatie voor slangen in 'De Wereld Draait…

Op vrijdagavond 17 september is de Leidse astronoom Joe Callingham te zien in een nieuwe serie op Discovery. ‘Killers of The Cosmos’ gaat over krachten in het heelal die ons bestaan kunnen bedreigen. Asteroïden, kosmisch puin, elektromagnetische wapens… De show behandelt elke bedreiging als potentiële…

Onze rechtsstaat brokkelt af, waarschuwt jurist Lilian Gonçalves-Ho Kang You in haar Cleveringa-oratie. Ze houdt een confronterende spiegel voor: aan het begin van de Tweede Wereldoorlog en tijdens de militaire dictatuur in Suriname dachten velen dat het niet zo’n vaart zou lopen.

Jasmina Mačkić, universitair docent aan het Europa Instituut, presenteerde haar onderzoek tijdens ‘The Dissident’, een live talk show die regelmatig wordt georganiseerd door World-Talks, op 24 mei 2018. De bijeenkomst draaide om de Nigeriaanse mensenrechtenactivist Justus Ijeoma, de oprichter van de…

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Promotor: T.H. Oosterkamp

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Bij een medische behandeling geldt een aantal rechten en plichten voor u en voor de arts of specialist. U hebt bijvoorbeeld het recht uw medisch dossier in te zien. De arts moet u bijvoorbeeld informeren over behandeling en onderzoek. U en de zorgverlener zijn verplicht zich aan de regels te houden.

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

De natuurkundestudenten van Stichting Rino toeren al sinds 2005 langs middelbare scholen met hun natuurkunde-roadshow. Tijd voor een nieuw programma: donderdag 4 maart beleeft hun nieuwste productie ‘Fast Forward Physics’ in Museum Boerhaave haar première. ‘Natuurkunde is meer dan wetten en formules…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.

Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Promotor: Prof.dr. M.K. Richardson

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

In the first part of this thesis we study the geometry of folding patterns.

Promotor: Prof.dr. S. Portegies Zwart

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Promotor: J.W. van Holten

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Promotor: J. Kuiper

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Promotores: G. Persoon, R. Schefold

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.