The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Promotor: C.J. ten Cate

Promotor: Roeland M.H. Merks

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Gamic Learning in East Asian Studies - Wat kunnen spellen ons vertellen over de manier waarop mensen leren?

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

Students Practicing Citizen Journalism

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Songbirds as vocal learners learn their songs and song preference from social tutors⁠. Tutor choice for both song and preference learning are important to characterize for understanding individual learning performance and cultural transmission of song⁠.

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

Promotores: Prof.dr. G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

Promotor: G.R. de Snoo

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

Heart failure is a major health care problem with high mortality.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Promotor: Prof.dr. B. van de Water

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

Promotor: Prof.dr. H.S. Overkleeft

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

The global agri-food system plays a critical role in food security and environmental issues.

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

This book explores the spiritual potential of faith, mysticism and transcendence in answer to the dangers of a mythologised state and the sacro-sanctification of (liberal) democracy and its rule of law.

Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.

To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

It researches (the possibilities for) the development of a set of principles and best practices for insolvency office holders by comparing multilateral treaties and soft law recommendations and national legislation within Europe.

Op 18 september 2019 verdedigde Huw Llewellyn zijn proefschrift 'An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.M. Blokker en prof.dr. L.J. van den Herik.

Does the presence of Ring-necked parakeets negatively influence feeding and feeding behaviour of native bird species on artificial bird feeders and if so, what are possible solutions?