For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.

In this thesis, we show that we can use Shimura’s CM theory to explicitly compute the Hilbert class field of any primitive quartic CM field.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…

Promotor: Peter Stevenhagen

Lipsius, Cleveringaplaats 1, 2311 BD, Leiden

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Calamus javensis is polymorphic. Morphometry and molecular approach resulted in all names used in the complex are regarded as synonyms of C. javensis except C. tenompokensis, which is retained as a distinct species. One variety is here recognized, C. javensis var. polyphyllus (including C. acuminatu…

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Lipsius, Cleveringaplaats 1, 2311 BD, Leiden

Promotor: Prof.dr. M. Ubbink

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Promotor: Prof.dr. E. Bouwman

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Hoe kun je leerlingen en studenten leren grip te krijgen op complexe ‘moerassituaties’? Oratie uitgesproken door prof.dr.ir. Fred Janssen bij de aanvaarding van het ambt van hoogleraar in de Didactiek van de Natuurwetenschappen aan de Universiteit Leiden op 19 juni 2017.

Promotor: Prof.dr. M. Ubbink

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.

The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.

This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…

De VVD stemde vorige week in met de nieuwe spreidingswet, waardoor gemeentes verplicht kunnen worden asielzoekers te huisvesten. Dat gebeurde nadat premier Rutte toezegde aan de slag te gaan met het inperken van de stroom asielzoekers. In hoeverre kan hij die belofte waarmaken?

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

Het aantal planeten waarop complex leven kan gedijen, is kleiner dan gedacht. Beloftevolle tweelingen van de aarde blijken bij nader inzien slechts beperkt levensvatbaar, stellen astronomen. Ignas Snellen van de Leidse Sterrewacht reageert in DeMorgen op het nieuws.

Promotor: Peter Stevenhagen

Sinds de gasbevingen in Groningen worden ‘vertrouwen’ en ‘overheid’ daar niet zomaar meer met elkaar geassocieerd. Dat leverde de casus op van de Honours Class ‘Gaswinning in Groningen en het fenomeen van vertrouwen in de overheid’, waarin studenten erachter kwamen hoe complex een begrip als ‘vertrouwen’…

This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…

On Friday 23 September 2016 the Leiden Complex Networks Network day, the LCN2 day, will take place in Leiden.

Koen Caminada over de noodzaak tot hervorming van de inkomstenbelasting in het Financieele Dagblad van 2 maart 2017.

Leren gaat het makkelijkst vanuit interesse. Maar die interesse is vaak meervoudig, en waaiert diverse kanten uit, stelt Sanne Akkerman, hoogleraar Onderwijswetenschappen. Hoe richt je het onderwijs daarop in? Oratie op 6 oktober.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Promotor: H.V.J. Linnartz

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

Bij sommige jongeren met suïcidale gedachten en gedragingen is er een subtiel maar significant verschil in de hersenstructuur, zo blijkt uit onderzoek. 'Het resultaat vertelt wellicht meer over de mechanismen bij suïcidaal gedrag in een specifieke subgroep', zeggen postdoctoraal onderzoeker Laura van…

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

This dissertation consists of two parts, with the common theme