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880 zoekresultaten voor “social a gene” in de Publieke website

• Gene regulation in embryonic development Onderzoeksoutput

  The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

• 
  A Langeveld

  Faculteit Geneeskunde

• 
  A Gorter

  Faculteit Geneeskunde

• 
  A. Gerasymenko Data & Security Advisor

  Leiden Learning and Innovation Centre

• Aflevering 12: The Selfish Gene Studium Generale

• Chromatin dynamics in single genes Onderzoeksproject

  Hoe beinvloed de structuur van één enkel gen de activiteit van genen die gevoelig zijn voor hormonen?

• 
  N.A.A. ten Veen Magazijnbeheerder

  ICT Shared Service Centre

• 
  A Mouret-Vein

  Faculteit Geneeskunde

• Exploring Grainyhead-like 2 target genes in breast cancer Onderzoeksoutput

  The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

• Image analysis for gene expression based phenotype characterization in yeast cells Onderzoeksoutput

  Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

• 
  Cees A. Swenne

  Faculteit Geneeskunde

• 
  Krista A. Milne Universitair docent

  Faculteit der Geesteswetenschappen

• 
  Augustinus Lycklama A Nijeholt

  Faculteit Geneeskunde

• A time-space translation mechanism for patterning the vertebrate anteroposterior axis Onderzoeksoutput

  My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

• 
  A Jonker-de Roode

  Faculteit Geneeskunde

• 
  A Gerritsen van der Hoop

  Faculteit Geneeskunde

• 
  Aianle a Abdulahi Beveiliging

  Wiskunde en Natuurwetenschappen

• mutagenesis to identify breast cancer drivers and therapy resistance genes in mice Onderzoeksoutput

  In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

• Identification and characterization of developmental genes in streptomyces Onderzoeksoutput

  Promotor: Prof.dr. G.P. van Wezel

• Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney Onderzoeksoutput

  Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

• 
  A.P.C Hooft Student-assistent

  Faculteit der Geesteswetenschappen

• 
  A. Presa Rodriguez Promovendus / gast

  Wiskunde en Natuurwetenschappen

• 
  S.C.A. Lefebvre Communicatieadviseur

  Faculteit der Sociale Wetenschappen

• Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production Onderzoeksoutput

  Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

• interplay between local three- dimensional chromatin architecture and gene expression Onderzoeksoutput

  Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

• Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer Onderzoeksoutput

  To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.

• The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions Onderzoeksoutput

  This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

• Mechanisms and consequences of horizontal gene transfer in cell wall-deficient cells of Kitasatospora viridifaciens Onderzoeksoutput

  The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

• analysis of Dof transcription factors controlling heading date and PPDK gene expression in rice Onderzoeksoutput

  Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

• Vascular tumor of bone and related lesions; from gene fusions to tumor models Agenda - 26 november 2024

  Promotie

• the cure: Towards Improving Hematopoietic stem cell based lentiviral gene therapy Agenda - 17 december 2024

  Promotie

• Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis Onderzoeksoutput

  In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

• Freedom of additional signals on genes: on the combination of DNA mechanics, genetics and translation speed Onderzoeksoutput

  DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

• Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity Onderzoeksoutput

  Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

• is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches Onderzoeksoutput

  The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

• Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based Onderzoeksoutput

  Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

• Modulation of plant chemistry by rhizosphere bacteria Onderzoeksoutput

  Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

• Exploring novel regulators and enzymes in salicylic acid-mediated plant defense Onderzoeksoutput

  Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

• Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer Onderzoeksoutput

  In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

• Next generation bacitracin: reimagining a classic antibiotic Onderzoeksoutput

  Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

• Resolving a bioindicator diatom species complex using genomic approaches for freshwater biomonitoring Onderzoeksoutput

  This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

• Sociale Zaken Sociale Wetenschappen

  Sociale Zaken is een online variant van de Londense Speakers' corner. Hierin reageren de wetenschappers van onze verschillende disciplines binnen de Faculteit der Sociale Wetenschappen op het nieuws. Via deze digitale zeepkist geven de sociale wetenschappers van de Universiteit Leiden zo elk hun visie…

• The social brain in middle childhood Onderzoeksoutput

  A neurobiological perspective on individual differences in social competence

• Sociale psychologie: Sociale experimenten en groepspolarisatie Cursus
• 
  W.C.A. Wigke Capri Arti Sukmana Putri PhD Kandidaat

  Faculteit der Sociale Wetenschappen

• Sociale veiligheid Young Academy Leiden

  Sociale veiligheid heeft alles te maken met een ondersteunende gemeenschap creëren

• Vrijheid van meningsuiting op ‘social media’ Onderzoeksproject

  Moet je alles kunnen zeggen op Twitter en Facebook? Is Instagram moreel verplicht foto’s te verwijderen van aanslagen? Moeten we toestaan dat terroristische groepering nieuwe leden werven op het internet?

• Sociale Wetenschappen Instituten

  Binnen de Faculteit der Sociale Wetenschappen zijn vijf instituten gevestigd:

• Sociale veiligheid Bestuur en organisatie

  Onze universitaire gemeenschap vormt het hart van onze academie. Het is voor de universiteit Leiden van groot belang dat haar medewerkers met plezier naar hun werk gaan en zonder belemmeringen hun werkzaamheden kunnen uitvoeren.

• Sociale veiligheid Dossier: Diversiteit en inclusie

  Bij FGGA willen we dat onze medewerkers zich in alle opzichten veilig voelen. We streven daarom naar een werkomgeving waar we elkaar met respect behandelen, waar we inclusie bevorderen en waar we ons uitspreken als we onveiligheid ervaren of er getuige van zijn.