1,335 zoekresultaten voor “even been met” in de Publieke website
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Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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Dynamics of the Oort Cloud and Formation of Interstellar Comets Santiago Torres Rodriguez
The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.
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Voordrachten
Voordrachten in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus (aug. 2017 – dec. 2023).
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GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
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BIOMOT: Motivational strength of ecosystem services and alternative ways to express the value of biodiversity
Do sustainability values play a role in motivating people to act for biodiversity in successful projects and in successful leadership action? And how could these values be incorporated in current economic valuation methods?
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Even kennismaken met de nieuwe assessor: 'Ik wist meteen: dit wil ik'
Met het nieuwe studiejaar is bij de Honours Academy ook een nieuwe assessor aangetreden: Maarten Kolpa. Wat doet een assessor eigenlijk? En wat kan hij voor studenten betekenen? Maarten vertelt erover in een interview. “Ik vind het belangrijk dat het studentenperspectief vooropstaat.”
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Realising the right to reproduce with assistance in South Africa
Op 10 november 2021 verdedigde Carmel van Niekerk-Jacobs het proefschrift 'Realising the right to reproduce with assistance in South Africa'. Het promotieonderzoek is begeleid door prof.dr. J.J. Sloth-Nielsen en prof.dr. T. Liefaard.
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Policy Review on Decoupling
Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.
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Ubar Kampung
The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…
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EPCEM 2001: Differences in the authorization process of GMOs in the EU and the USA
This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…
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Rare Earth Supply Chain and Industrial Ecosystem: A Material Flow Assessment of European Union
1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…
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Positioning of current Environmental tools & an outlook to the future
Review of new technical decisionsupport systems in the environmental field, and application in water management decission processes.
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Iber Kasehatan in Sukamiskin: Utilisation of the Plural Health Information and Communication System in the Sunda Region of West Java, Indonesia
This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.
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This is life: some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Exploring strange new worlds with high-dispersion spectroscopy
Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…
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Evaluation of Different Design Space Description Methods for Analysing Combustion Engine Operation Limits
Promotor: Prof.dr. T.H.W. Bäck
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Not so smooth after all: resolving dust and gas structures in protoplanetary disks
A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.
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Emergence of rebellious digital press in Chile: Divergence, engagement and impact. Journal of Communication
A new publication on changes in the relationship between news and their public in Chile
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Applying data mining in telecommunications
This thesis applies data mining in commercial settings in the telecommunications industry.
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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The optimization and scale-up of the electrochemical reduction of CO₂ to formate
Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…
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The heart of oxygenic photosynthesis illuminated
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
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Periodic pulse solutions to slowly nonlinear reaction-diffusion systems
Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Cold gas in distant galaxies
The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.
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Evolutionary diversification of coral-dwelling gall crabs (Cryptochiridae)
Promotor: Prof.dr. E Gittenberger, Co-Promotores: C.H.J.M. Fransen, B.W. Hoeksema
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The music of language: exploring grammar, prosody and rhythm perception in zebra finches and budgerigars
Promotor: C.J. ten Cate
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Gauge theory and nematic order : the rich landscape of orientational phase transition
Promotor: J. Zaanen
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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The hunt for frozen organic molecules in space
Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Stochastic and Deterministic Algorithms for Continuous Black-Box Optimization
Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.
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Principal algebraic actions of the discrete Heisenberg group
Promotor: Prof.dr. W.T.F. den Hollander
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Probing molecular layers with low-energy electrons
Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…