This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Promotor: Prof.dr. M.A.G.J. Orrit

To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.

Forgotten Lineages explores the paths through which generations of formally enslaved and their descendants gradually forgot their past of enslavement under Dutch and British imperial rule and became local subjects in Sri Lanka and South Africa. It explores why and how forgetting rather than memory became…

Career Event

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

Promotie

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

Onderstaand een overzicht van alle vakken die door de afdeling Economie worden verzorgd.

Alumnus Jan Versteegh vertelt onder andere over hoe de samenwerking tussen advocatenkantoor TeekensKarstens en Leiden Law School destijds tot stand is gekomen in ons maandelijkse flitsinterview.

Dirk Visser, hoogleraar intellectueel eigendomsrecht, en Hanneke Spath, hoogleraar burgerlijk recht aan de Radboud Universiteit, doen in het mei-nummer van Ars Aequi een oproep om (nu echt) te komen tot een Boek 9 BW met een codificatie van (alleen) de vermogensrechtelijke aspecten van de intellectuele…

Op dinsdag 17 november organiseert het CML en het ministerie van Buitenlandse Zaken een debat met staatssecretaris Timmermans van Europese zaken. Onderwerp van het debat is de komende klimaatconferentie in Kopenhagen en de rol van de Europese Unie. De bijeenkomst heeft een informeel karakter en de voertaal…

Promotie

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

Gamic Learning in East Asian Studies - Wat kunnen spellen ons vertellen over de manier waarop mensen leren?

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.

In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…

EXIOBASE is a global, detailed Multi-regional Environmentally Extended Supply and Use / Input Output (MR EE SUT/IOT) database. It was developed by harmonizing and detailing SUT for a large number of countries, estimating emissions and resource extractions by industry, linking the country EE SUT via…

We analyse the link between media consumption and the attitudes toward people living with HIV/AIDS in Chile. We used data from a sample of 1000 people, obtained in the 2011 wave of the World Values Survey (WVS). We use a logistic binary regression model by maximum likelihood. Our results suggest that…

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

In 2013-2014, CML published over 100 papers, contributed to various international sustainability debates, renovated our building and educated thousands of students from all over the world through our MOOC. These accomplishments and many more are highlighted in this booklet, CML wish you a pleasant…

Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

In 2015, CML published over 70 papers, contributed to the United Nations conference on climate change in Paris, won awards and advised the Dutch government on the safe use of pesticides. CML awarded 11 PhDs and taught students from all over the world how to contribute to sustainability. We wish you…

This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.

Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk

How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…

Sinds 2009 behaalden 84 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.

Stikstofexpert Jan Willem Erisman legt de stikstofplannen van ministers uit. En vertelt of we hiermee de stikstofcrisis te boven komen.

Het coronapaspoort: dwang, drang of publiek belang? Bij de afweging tussen veiligheid en vrijheid komen hoe dan ook grondrechten in het gedrang. Dat mag, vinden deskundingen, mits een maatregel noodzakelijk en proportioneel is.

Grensverleggend geschiedenis leren.

Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.

Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

How do nanoparticles bioaccumulate and biodistribute in organisms?

eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?

Studievoorlichting

Studievoorlichting