Identifying and explaining change in the structure of central state bureaucracies and the determinants of survival of individual public organizations are two closely related areas of research in public administration. We aim to bridge the gap between these two main strands of studies of organizational…

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Can a newly developed, app-based, personalized maintenance program enhance the effectiveness of the exposure-based one-session-treatment for children with a specific phobia?

This dissertation takes a technological approach to ceramic production and provides a fine-grained view of the circum-Caribbean region.

A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.

Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.

Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.

Andrei Poama, Assistant Professor at Leiden University, published a piece in the journal of Political Philosophy about social injustice, disadvantaged offenders and the state's authority to punish.

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

This research deals with the royal houses of the Vijayanagara Empire and four of its successor states: Ikkeri, Tanjavur (under both the Nayaka and Bhonsle rulers), Madurai, and Ramnad. This study is thus concerned with dynastic politics and imperial legacies in south India between the 14th and 18th…

Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

This research project focuses on the interaction of Buddhist institutions, Chinese central and local governments, and local gentry in the 'transforming temples into schools' movement.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

PURPOSE: The aim of the study was to develop a cheap and fast method to produce hollow microneedles and an applicator for injecting vaccines into the skin at a pre-defined depth and test the applicability of the system for dermal polio vaccination.

Promotor: Prof.dr. G.P. van Wezel

The European Commission has officially established Euro-BioImaging – which provides life scientists with open access to a broad range of technologies and resources in biological and biomedical imaging – as a European Research Infrastructure Consortium (ERIC). The Cell Observatory in Leiden is part of…

Analysing the ways in which immigration structurally challenges and changes the organization and conceptual boundaries of national welfare states.

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

In The Hague, the Leiden Centre of Data Science (LCDS) in close collaboration with the Centre for Professional Learning (CPL) is developing a Legal Technologies programme. They do so in cooperation with three faculties of Leiden University, namely the Faculty of Governance and Global Affairs (FGGA),…

Spirited narratives of purpose and progress: church-society engagement alongside the (Company-) state

In a modernist interpretation of migration controls, nation states play a major role. This book challenges this interpretation by showing that comprehensive migration checks and permanent border controls appeared much earlier, in early modern dynastic states and empires, and predated nation states by…

Promotor: Prof.dr. J. Kuiper

On 5 June, Maarten Aalbers defended the thesis 'The balancing of general interests in EU State Aid Law: blurred lines between the prohibition and the compatibility of aid'. The doctoral research was supervised by Pieter van Cleynenbreugel and Stefaan van den Bogaert.

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

This project aims to assess the risk of spread of antimicrobial resistance genes in the environment derived from currently used synthetic biology approaches in the field of drug discovery.

An international team from the Netherlands, France, Norway and Austria demonstrate how new sequencing technologies can be used to efficiently generate the genome, DNA, sequence of an endangered animal, the European Eel.

On 1 September 2022 Güldeniz Kibris successfully defended a doctoral thesis and graduated.

This article explores how ISIS and the Taliban have fostered support through their parallel legal systems.

Tens of thousands of soldiers and civilians have died as a result of Russia’s invasion of Ukraine in February 2022 and the continuing armed conflict. Many forms of critical infrastructure have been destroyed. Much of this devastation has been caused by weapons that utilise forms of artificial intelligence…

On 13 December 2023 Alf Farabi successfully defended a doctoral thesis and graduated.

On 23 October 2019, Yoram Stein defended his thesis 'Spinoza's Theory of Religion: The Importance of Religion in Spinoza's Thought and Its Implications for State and Society'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. A.A.M. Kinneging.

On 7 May 2020, Jolanda van der Vliet defended her thesis 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. J.J.C. Voorhoeve.

How do governments distribute resources across economic sectors during a crisis? And why do some sectors receive more than others? The recent COVID-19 pandemic has highlighted the urgency of these questions. In this paper, we explore the extent to which a political economy…

Technological developments are rapidly advancing. The Leiden Legal Technologies Program was on the agenda of the Advisory Committee at their second meeting held on 15 October. The decision to start the program in January 2021 was taken unanimously. It was the official moment to announce the completion…

Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…

On 23 April 2021, Professor Alfred Vertegaal from the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Unraveling and exploiting cellular communication codes’. Vertegaal used the opportunity to describe how research in the field…

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

The Europa Instituut is pleased to announce that this week a new handbook “EU State Aids” (31 Chapters, 1500 pages) was published.

Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…

The transition from single cells to multicellular organisms was a key step in evolution. Researchers from Leiden and Amsterdam developed a mathematical model that explains how this transition may have come about. They suspect cooperating cells may correct each other’s mistakes. Publication in eLife…