Bringing together institutes and research groups, how do you do that? The Faculty of Science set up a joint research theme and financed three PhD positions. After four years, the profiling programme Endocannabinoids expires. ‘It really brought us together, and the collaborations remain.’

While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Possible improvements for the assessment of abiotic depletion in LCA.

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.

On 20 September 2023 Mark van de Water successfully defended a doctoral thesis and graduated.

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

My PhD thesis investigates the ecological significance of resistance against drought-induced air bubble formation inside the water conduits of plants (embolism), and the plasticity and functional aspects of stem anatomical traits in woody and herbaceous species.

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

Projects in the department of Industrial Ecology

Our facilities cover:

Pathways of toxicity

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

Biodiversity in the Netherlands is having a tough time. Professor of Natural Capital Koos Biesmeijer combines research with practical advice: from the greening of industrial parks to solutions inspired by hi-tech nature. Inaugural lecture 9 March.

Mapping sanitary infrastructure in large urban societies in the Low Countries, 1200–1900

What are the effects of light pollution from cities and bridges and noise pollution from passing vessels and nearby road traffic on migratory fish passage and spawning in rivers?

In this project we ask: how does pollution manifest as part of different practices, both socially and materially.

How did Angkor interact with regional urban centers? How did the settlement system impact the society's agricultural system and regional resilience?

PRINCE (for Policy Relevant Indicators for Consumption and Environment) was a three-year project set up to explore ways to improve and expand the set of indicators used to estimate the environmental impacts linked to Swedish consumption, both within Sweden and abroad. Any new methods and indicators…

Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.

PhD candidate Marc Baggelaar of the Leiden Institute of Chemistry (LIC) graduated cum laude on Thursday 6 April. His thesis on the endocannabinoid system in the brain is very comprehensive and of high quality, according to the jury. ‘A very talented young scientist, that definitely belongs to the top…

The central research question focuses on identifying shifts in the urban social network in terms of private, semi-public and public space by means of mapping the spatial distributions of wells and cesspits in the town of Haarlem in the course of the pre-industrial period (1200-1800). Shifts may be indicative…

PhD defence

An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.

De decentralisaties van de zorg aan langdurig zieken en ouderen, jeugdzorg, en werk en inkomen die vanaf 2015 zijn doorgevoerd in Nederland hebben geleid tot een transitie van een centraal naar een lokaal stelsel van zorg en welzijn. Deze transitie beoogt zorg en ondersteuning dichter bij de inwoners…

Curious about how sustainability fits into our university's strategic plan, or how much energy and water we consume? Read about it here.

Mechanisms fro drug resistance

Analysis of drug adversity

Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…

The Advisory Board is an external Advisory Council, to advice the Board of Directors of CML about general strategies, research and education activities and evaluation procedures (Dutch: visitatie).

Industrial Ecology

High throughput microscopy

What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'

The Dutch Development Bank's new SDG loan fund for green energy in the global south may not be as positive as it seems. Anthropology professor Marja Spierenburg raises concerns about its potential impact on local communities.

Lecture, PCNI Research Seminar

In the large gas clouds between the stars, chemical reactions take place under extreme conditions, giving rise to both small molecules, such as water and common salt, as well as large complex molecules that can serve as the building blocks of life. This is known as astrochemistry and it is something…

The hinterland of important centres like Petra (Southern Jordan) can provide essential information that contribute to the understanding of their rise, expansion and decline.

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

Conference

Lecture