6,432 search results for “based” in the Public website
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Formulation of Peptide-Based Cancer Vaccines
PhD defence
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Anne Land-ZandstraScience
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Irma Mosquera ValderramaFaculteit Rechtsgeleerdheid
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Maarten KampertFaculteit der Sociale Wetenschappen
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Mojgan Chaichian MalekiScience
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71 new students start in Science Business courses
The new S&RBB minor turned out to be rather popular. Together with the master applicants for the Fundamentals course, S&RBB started with 71 new students, the highest number ever.
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Simcha Jong joins the SBB team
As of February the SBB team has expanded. Simcha Jong has joined the team as a Professor and Director of Science Based Business.
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Harmen Jousma catapults students onto the job market
Practise in the Board Room and getting start-ups through difficult times. Students of Harmen Jousma, lecturer in Science Based Business, learn about the art of doing business. Jousma is one of the three nominees for the Leiden Teaching Prize.
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Advancing image-based localization of lipid-based nanomedicines for the exploration of targeted drug delivery
PhD defence
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Characterization and skin permeation of ketoprofen-loaded vesicular systems
PURPOSE: To determine the effect of elasticity on the skin permeation of ketoprofen from surfactant-based vesicular formulations and elastic liposomes.
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Tsuvadi Gender: A mixed form- and semantic-based system
Lecture, This Time For Africa! series
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Global fitness maximising approaches to evaluate the trade-offs involved in the evergreen and deciduous conundrum
Which traits and/or trade-offs determine benefits of being deciduous or evergreen?
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Producing affective language: experimental and corpus-based approaches
Lecture, LACG Meetings
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Physiological based CPAP for preterm infants at birth
PhD defence
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Radiomics-based machine learning classification of bone chondrosarcoma
PhD defence
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Mechanism-Based Inhibitors and Probes for Neuraminidases
PhD defence
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mRNA and Drug Delivery with Lipid-based Nanoparticles
PhD defence
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Flow-based Arterial Spin Labeling: From brain to body
PhD defence
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
PhD defence
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Development of nanoparticulate adjuvants based on aluminium salts
PhD defence
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Peptide-Based Probes for Protein N-Methyltransferases
PhD defence
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Chemical Protein Synthesis: from Nanobodies to Activity-Based Probes
PhD defence
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Affinity-Based Profiling of the Adenosine Receptors
PhD defence
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Squaramide-based Interpenetrated Networks for Load-bearing Applications
PhD defence
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Value-based and data-driven vestibular schwannoma care
PhD defence
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A managerial perspective on value-based healthcare
PhD defence
- THNK – A science-based checklist for effective science communication
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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LIC Lecture: Structure-based development of immunoproteasome inhibitors
Lecture
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Evidence-based treatment of central serous chorioretinopathy
PhD defence
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Mechano-transduction mediated by integrin-based adhesion complexes
PhD defence
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Assemblage and functioning of bacterial communities in soil and rhizosphere
Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Modelling the role of cytotoxic T lymphocytes in tumour regression
Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.
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Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
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International consortia: the future for science?
We increasingly look at international consortia to come up with scientific and technological advances that are needed to address global challenges in areas such as health, the environment and clean energy. However, organising these consortia involves unique challenges. To identify these challenges,…
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Martijn van der LiendenScience
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Simcha Jong Kon ChinScience
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Working with SBB Interns. By Roel Bulthuis of Merck Serono
Since 2008 every half a year an SBB student starts with an internship for Merck Serono Ventures in Geneva. Head of the company Roel Bulthuis selects and works with the SBB interns and shares his experiences as an employer. He is very pleased.
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel