Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

How can we stay fit during hybrid working?

Where in the model of contemporary art, which can be described as a hybrid and joint undertaking between artists, institutions, curators, theory and discursivity, is the actual 'object' of art located and generated? Where and by whom and in what configuration of positions is it produced? Who or what…

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

High Performance Computing (HPC) is becoming ever more important as a research tool in many research areas across all research domains. A University facility, providing serious computational capabilities, combined with easy and flexible local access, is a strong advantage for these research areas. It…

Leiden University College The Hague (LUC) offers a 3-year Bachelor's programme with a focus on Global Challenges: Peace & Justice, Sustainability, Diversity and Prosperity. The programme offers room for flexibility; you get to specialize in a major of your choice and combine this with a minor or electives.…

This open access volume surveys the state of the field to examine whether a fifth wave of deterrence theory is emerging. Bringing together insights from world-leading experts from three continents, the volume identifies the most pressing strategic challenges, frames theoretical concepts, and describes…

COI@Leiden organises activities and events throughout the year. These include a monthly seminar series on topics relating to conflict resolution and PhD labs to assist COI students in developing their research skills.

Workshop

Within the Comparative Religion Network staff and graduate students from LIAS-LUCSoR (and beyond) discuss ongoing work and cooperate on key issues in the comparative and systematic study of religion.

Study of human cultures using computational approaches

Electives offer students the opportunity to further specialise and deepen in specific aspects of leadership.

Historian Robert Stein is a lecturer in Medieval History. He was recently awarded the Senior Teaching Qualification. What did he learn from the STQ track and what lessons does he plan to apply in his hybrid lecture room?

The Leiden Institute of Advanced Computer Science (LIACS) is a centre of excellence for multidisciplinary research and education in computer science and artificial intelligence (AI).

Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

This year is the 444th anniversary of Leiden University and we are celebrating this with the residents of the two cities in which the University has a presence: Leiden and The Hague. We are therefore holding an exhibition about the University and its connections to the city in the Atrium of City Hall…

The Women, Peace and Security (WPS) agenda arising from United Nations Security Council Resolution 1325 has reached a critical juncture in its short 20-year history. Despite comprising ten resolutions designed to bolster the agenda and expand its scope and normative power, serious challenges to the…

In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

Promotor: Prof.dr. H.J.A. Rottgering, Co-promotor: David Sobral

Together with colleagues from the Stimson Center and in the framework of the Global Governance Innovation Network, Dr. Joris Larik has recently published the report

Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.

The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Promotor: Prof.dr. G.R. de Snoo

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Restructuring and insolvency laws play a pivotal role in addressing the often conflicting interests of stakeholders of financially distressed companies. Whereas financial distress is an inherent risk of entrepreneurship in market-based economies, legal tools serve an important role to ensure an orderly…

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?

How to facilitate the translation of science into innovation

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

Many conflicts in Africa have been studied and described as location and time bound. Yet conflict is rarely confined and contained, and instead reaches across communities, borders, and generations.

Introduction to Medieval Europe 300–1500 provides a comprehensive survey of this complex and varied formative period of European history, covering themes as diverse as barbarian migrations, the impact of Christianisation, the formation of nations and states, the emergence of an expansionist commercial…

In the academic year 2023-2024 the SRS interdisciplinary programme will offer four courses for interested students who are entering the third year of their Bachelor's degree. You can sign up for these courses in your elective (minor) space. You can follow the courses individually as an elective, or…

Promotores: G.A. Persoon, H.H. de Iongh

On 23 February 2022, Cale Davis defended the thesis 'Prosecutorial Discretion in International Criminal Justice'. The doctoral research was supervised by Prof. C. Stahn en Dr. J.C. Powderly.

How public service motivation and professionalism affect decision-making in dilemma situations. Individuals who work in the public sector see themselves confronted with conflicting values, contradictory demands, and the need to serve an at times difficult to define ‘public interest’.

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

This book examines the history of The Netherlands in a way that connects global processes to local developments.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Machine Learning is becoming a more and more substantial technology for industry.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

The field and the classroom invites ethnographers to engage with critical and engaged pedagogies. Breaking down the barriers between fieldsite and lecture hall, this research cluster aims to interrogate the structures and values that shape anthropological and sociological education today.

On 24 January 2024, Vethaak defended the thesis 'Empirical Analysis of Social Insurance, Work Incentives and Employment Outcomes'. The doctoral research was supervised by Koen Caminada and Pierre Koning.