The subject areas covered encompass functional genomics, signal transduction, cellular differentiation, development, host-microbe interactions and animal behaviour.

Lecture

Development of scenarios for 2050 detailed in an IO framework

What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?

We are doing all we can to save energy at the university. Find out how you as a member of staff or student can do about energy and help reduce CO2 emissions.

Research in the POD-group addresses all features of random phenomena – modelling, structuring, analysis, control, optimisation – and covers both fundamental and applied aspects.

PhD defence

PhD defence

An overview of the research at the Biologics Formulation group

Twenty years from now, the world population is estimated to be around 9 billion people (now 8 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this population will result in an enormous increase in the demand for food, consumables, water…

The LACDR represents the core of bio-pharmaceutical research at Leiden University, and we interact closely with our partners:

Joost Batenburg is a mathematician and computer scientist who works to build bridges to other disciplines. He hopes to bring intelligent software to fields where it can make a difference. Conversely, he also seeks connections to the disciplines that are needed to make AI a success.

Isotopes on exoplanets, a more efficient memory for data centres or new molecules that work against the Zika virus and HIV. Which PhD candidate has written the most impressive dissertation of 2023? The jury of the C.J. Kok Jury Award faces the challenging task of deciding that. Meet the nominees of…

The local ordering of atoms at the surface of a metallic particle determines its catalytic activity and selectivity. As energy systems of the future will be based on efficient catalytic conversion of small molecules in closed cycles, we study how structural effects of catalysts can be used to our ad…

The research programme Probability Theory focuses on probability theory and on operations research.

Leiden Professor of Translational Rheumatology Hans Ulrich Scherer has one foot in the clinic, where he helps patients, and the other in the lab, where he supervises researchers. He bridges these two worlds in his hunt for autoimmune rheumatic diseases.

Promotor: J.N. Kok, Co-promotor: M.S. Lew

When companies violate women’s human rights.

Key publications of the Biologics Formulation group

This dissertation presents new cryptographic protocols, which can be divided into two families.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

Promotor: J.W.M. Frenken

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?

There is considerable need for improved skin models to develop safe and efficient drugs for skin delivery as well as for cosmetic and chemical product testing on the skin.

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

Promotores: W. Jiskoot, F. Ossendorp

The potential of liposomal cancer vaccines

Heart failure is a major health care problem with high mortality.

Videos shared on social media have become important evidence to hold perpetrators of human rights violations accountable. What does this increased use of digital open source evidence mean for the quality of international human rights accountability? Through an innovative experimental design, this project…

We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.

Uncertainty and noise are frequently-encountered obstacles in real-world applications of numerical optimization. The practice of optimization that deals with uncertainties and noise is commonly referred to as robust optimization.

During the development of the Humanities Campus, as many 'green choices' as possibile are being made. This concerns the buildings as well as the surrounding area. Making the campus more sustainable is measured using the BREAAM.NL method.

Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

A scenario building web-tool and knowledge package to enable multi-level decision making for the transition to the Circular Economy

This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…

Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information⁠. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go⁠.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood

Living together in a residential setting adds another dimension to this learning, as our students have to learn to live with others who may not share the same daily routines or standards.

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

Aviation safety is of global concern. Yet 43% of countries worldwide lack the expertise and administrative capacity to ensure effective safety oversight of the aviation activities for which they are responsible under international law.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?

Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek

Kohei Suzuki, Assistant Professor at Institute of Public Administration, researched, together with two other authors, whether public managers with private sector experience have more core managerial values.

Promotor: M. Ubbink, Co-promotor: G. Siegal

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…