6,432 search results for “based” in the Public website
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Applications of multisource data-based dynamic modeling to cell-cell signaling and infectious disease spreading
The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…
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of Carbohydrate-Active Enzymes: Key Insights for Sustainable Bio-Based Processes
PhD defence
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teachers in professional learning communities on differentiated teaching based on cognitive differences of students
What relationships exist between different types of PLCs and cognitive differentiated teaching?
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Pharmaceutical-Grade Sugars and their Interference with Light Scattering-Based Analysis of Protein Formulations
PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.
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Multi-sensor Earth Observation Products through phenology and trait-based priors
What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?
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Vincent Koeman
Science
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clearance in children using population pharmacokinetic and physiology based pharmacokinetic modeling approaches
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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teachers: using a modular, success-oriented approach to make a context-based educational reform practical for implementatiion in Dutch biology education
For a successful implementation of an educational reform, teachers need to regard the proposal as being practical. I used a modular, success-oriented approach to make a context-based reform practical for implemtentation in Duthc biology education. educational reform, modular, teachers, biology, success-oriented,…
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consistent methodology for assessment of the combined effects of metal-based chemicals to lettuce (Lactuca sativa L.)
How to improve the method in quantifying the combined effects of metal-based chemicals?
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Learning to look at LiDAR: combining CNN-based object detection and GIS for archaeological prospection in remotely-sensed data
The manual analysis of remotely-sensed data is a widespread practice in local and regional scale archaeological research, as well as heritage management.
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Cost-utility of a guided Internet-based intervention in comparison with attention only for people with HIV and depressive symptoms: A randomized
We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.
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Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
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Tolkien and fiction-based religions
Markus Altena Davidsen’s PhD dissertation is the first major study of Tolkien Religion. In it, he analyses the religion that is based on the stories by acclaimed British fantasy author J.R.R. Tolkien. He also discusses how fiction itself can become religious. Davidsen will defend his dissertation on…
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What's Next? Experience-based design
With the What's Next? series we hope to inspire current Media Technology MSc students, show the variety of paths taken after the studies, and bring together alumni. Editions of the series are generally organized around a particular theme by Media Technology MSc students themselves, and followed by social…
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Novel system-inspired model-based quantum machine learning algorithm for prediction and generation of High-Energy Physics data
Assistant Professor Vedran Dunjko and his team received a gift from Google to support their quantum research. The research focuses on whether quantum computers can provide new ways of understanding the mysteries of high-energy physics.
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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Archaeology thanks to computer-based research
A mix of data research, artificial intelligence and archaeology led to lively discussions on 31 January. On that day the unique event 'AI & Data Science @ Archaeology' took place in which the Data Science Research Programme (DSRP), SAILS and the Faculty of Archaeology joined forces.
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Towards evidence-based migration policymaking?
From March 2023, political scientist Katharina Natter (Leiden University) will lead part of an ambitious project called PACES, funded by Horizon Europe and coordinated by Simona Vezzoli (ISS). PACES is an innovative, inter-disciplinary and multi-level research project that offers a groundbreaking approach…
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Archaeology thanks to computer-based research
A mix of data research, artificial intelligence and archaeology led to lively discussions on 31 January. On that day the unique event 'AI & Data Science @ Archaeology' took place in which the Data Science Research Programme (DSRP), SAILS and the Faculty of Archaeology joined forces.
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Weighing heavenly bodies based on bending light
Many astronomers suspect that most of the matter in the universe is invisible. So how can you weigh dark matter if you can't actually see it? Professor Henk Hoekstra is looking for a solution. Inaugural lecture 25 June.
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structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based metabolomics approach
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Inaugural lecture: Where science meets business
What is and should be the role of universities in supporting business? How can business benefit more of relationships with science? And what is the role of policy makers in supporting a productive relationship between science and business? Professor Simcha Jong Kon Chin examines the interactions between…
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Anne Stiggelbout
Faculteit Geneeskunde
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Blog Post | Towards an AI-based Counter-Disinformation Framework
In this blog post, Linda Slapakova discusses the various roles that AI plays in counter-disinformation efforts, the prevailing shortfalls of AI-based counter-disinformation tools and the technical, governance and regulatory barriers to their uptake, and how these could be addressed to foster the uptake…
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Science Based Business expansion adds to international profile
Two new Assistant Professors are joining Science Based Business (SBB) this Autumn. ‘Xishu Li and Jian Wang are the first two Assistant Professors we recruited. This is an exciting, crucial next step for SBB,’ said Professor Simcha Jong who joined Leiden University as the Director and first Professor…
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Registration for the Science Based Business specialisation is now open
The registrations for the Science Based Business specialisation of the Fall 2017 (Management track, starting in September) has now been opened, and it is thus now possible to apply. The ability to apply for the New Technology Ventures track will also follow soon.
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Leiden celebrates establishment of new Chair in Science Based Business
By delivering his inaugural lecture titled ‘Where Science Meets Business,’ Simcha Jong accepted his appointment as Leiden’s first Professor of Science Based Business. In his lecture in the Large Auditorium of the Academy Building, Simcha argued that broad universities with a focus on fundamental research,…
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‘Communication, too, has to be based in science'
Science communication is a lot more than writing a column or giving a lecture now and then. The communication itself also has to be firmly based in sound scientific research, is the message of Professor Ionica Smeets in her inaugural lecture.
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AI recognizes anxious youth based on their brain structure
A unique multicenter study, including about 3,500 youth between 10 and 25 years old from across the globe, shows that artificial intelligence - specifically machine learning - is able to identify individuals with anxiety disorders based on their unique brain structure.
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Income-based fines coming in the Netherlands?
In many European countries, the amount of a fine is based on the level of your income. This already exists in Finland, Sweden, Germany, France, and Spain. The Dutch Lower House is now contemplating the introduction of such a system.
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Cell-based medicinal products: grant rejected, paper published
Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.
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Leiden based research confirms systematic and excessive violence in Indonesia
New research has confirmed that the Dutch military used systematic, extreme violence against Indonesians. In his book Soldaat in Indonesië (Soldier in Indonesia), to be released at the end of October, historian Gert Oostindie draws the same conclusions using different sources. He presents new findings…
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Femke Stad
Faculteit der Sociale Wetenschappen
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Eefje de Goede
Science
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Danielle Oprel
Faculteit der Sociale Wetenschappen
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Anika Bexkens
Faculteit der Sociale Wetenschappen
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Interpreting lithic raw material variability in Middle Palaeolithic contexts
A modeling approach with applications to the Bau de l'Aubesier (Southeastern France)
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National Meat Free Week: the main reasons to switch to a plant-based diet
National Meat Free Week (Nationale Week Zonder Vlees, 7–13 March) is an initiative to reduce meat consumption. Assistant professor Paul Behrens is studying what impact a change in our food consumption would have on the world. What, according to him, are the main reasons to switch to a (mainly) plant-based…
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Inquiry-based learning: smart tools help lecturers adapt their courses
Engaged, active students who can see the links within their discipline. These are key aims of the University vision on teaching and learning, but how do you achieve them? An interdisciplinary research team led by ICLON has developed an inventive method that helps lecturers do just that.
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Carlotta Rigotti participates in international workshop on image-based sexual abuse
As eLaw Postdoc researcher exploring the multiple intersections between law, gender, and technology, Carlotta Rigotti has recently participated in a groundbreaking international workshop focused on combatting image-based sexual abuse (IBSA) at the CAIS premises in Bochum, Germany.
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Workshop ‘Science Based Rules on Plastic: Regulating Plastic Pollution’ at Lorentz Center
From 27 to 31 January, a workshop on the regulation of plastic pollution based on scientific evidence will be held at the Lorentz Center in Leiden.
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How plant-based diets not only reduce our carbon footprint, but also increase carbon capture
Almost 100 billion tons of CO₂ could be pulled out of the atmosphere by the end of the century. That is, if high-income countries switch to a plant-based diet. The double carbon profit of returning farmland to its natural state would equal about 14 years’ worth of agricultural emissions, researchers…
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Leiden archaeologists create open educational resources on agent-based modeling
The past two years, Laura van der Knaap and Professor Karsten Lambers worked on creating open teaching materials on agent-based modeling, funded by Erasmus+ and in collaboration with Danish, Irish and Dutch partners. Programming is an important skill involved in this, which is often seen as intimidating…
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Americans more likely to finance presidential candidate with broad support base
Americans more often donate funds to a presidential candidate if the campaign is backed by financiers from different, recognised social groups. This is the conclusion of Leiden researcher Vincent Traag in an article in Plos One published on 14 April.
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Sustainability prize for research into the effects of a plant-based diet
Paul Behrens and his team have won the Frontiers Planet Prize of half a million euros for their research into the effects of switching to a plant-based diet.
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Leiden University contributes to evidence-based land policy in Timor-Leste
For the next six months the Van Vollenhoven Institute of Leiden University, together with The Asia Foundation (TAF), will develop a tool for evidence-based land policy in Timor-Leste.
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Wimar Bolhuis chief economist at research-based consultancy firm Ecorys
As chief economist, Bolhuis will conduct research on topical economic issues. Besides this position, he will remain active as a lecturer at the Department of Economics at Leiden Law School.
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Prestigious Journal of European Public Policy selects Leiden-based research for Special Issue
The Journal of European Public Policy has dedicated this year’s Special Issue to the theme of European Union Enlargement and Integration Capacity, on the suggestion of Dr. Antoaneta Dimitrova, senior lecturer at the Institute of Public Administration of Leiden University. Moreover, the Special Issue…