1,459 search results for “personalized medicine” in the Public website
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LACDR excels at the FIGON Dutch Medicine Days
The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken
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Research groups
The research at The Metabolomics & Analytics Centre is centered around developing innovating analytical methods to enable metabolomics-driven systems biology in personalized health strategies.
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NWO grant for smart software that searches for new medicines
Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…
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Discoverer of the Year bridges science and medicine
Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…
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Eduard Fosch Villaronga: 'Robots are mainly for the average person'
IT lawyer Eduard Fosch Villaronga wants to promote diversity and inclusiveness in AI research. And that's really important, because he has observed how artificial intelligence - from Twitter to walking robots - is prejudice in terms of race, gender and sexual orientation.
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Johan de Fijter
Faculteit Geneeskunde
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Tinde van Andel
Science
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Pieter Reitsma
Faculteit Geneeskunde
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Arko Ghosh
Faculteit der Sociale Wetenschappen
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Mario van der Stelt
Science
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Madeline Kavanagh
Science
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NWO grant for smart software that searches for new medicines
Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…
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PROPER: ‘Near-patient’ prostate cancer models for the assessment of disease prognosis and therapy
How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?
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Assessing the safety of chemicals and medicines without laboratory animals
One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.
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How public money for science leads to new medicines
Public funding for fundamental research is essential for innovation and the development of new medicines. This is demonstrated by Professor Science Based Business Simcha Jong and his colleague Hsini Huang after studying US federal funding restrictions for stem cell research under President George W.…
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Book about 200 years of medicine in Leiden
The book ‘Geleerde Zorgen: twee eeuwen academische geneeskunde in Leiden’ (‘Learned Care: two centuries of academic medicine in Leiden’) was presented on 16 December to Annetje Ottow (President of the Executive Board of Leiden University) and Pancras Hogendoorn, Dean and member of the Executive Board…
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International President Médicins Sans Frontières visits LUC The Hague
Last Thursday , Dr. Joanne Liu, the International President of the Médicins Sans Frontières (Doctors without Borders), visited LUC The Hague as part of her visit to Universiteit Leiden. Dr. Liu spoke with four of our students, who shared their experiences as volunteers working with refugees all over…
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Microfluidics for high-throughput liposome formulation for personalized cancer vaccination
Liposomes hold great promise for peptide-based personalized cancer vaccination, especially when administered intradermally. However, current liposome preparation methods are very time consuming (resulting in long development times per formulation), whereas personalized cancer vaccination requires very…
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‘Mysterious Meniere’s disease is the poor relation in medicine’
Meniere’s disease, a disorder of the inner ear, was first described back in 1861, but there’s still no good test or treatment for it. Tjasse Bruintjes, Professor by Special Appointment of Ear, Nose and Throat Surgery, wants more attention for this mysterious disease. And he wants to tell his fellow…
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Development of Comprehensive and High-throughput metabolomics techniques
A major goal of ABS research is to overcome one of the major bottle-necks in metabolomic research: the lack of a high-throughput infrastructure in which thousands of samples can be processed in a standardized and cost-effective way (max. a few tens of Euro’s per sample for a full metabolome profile).…
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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Phenoconversion
Pharmacogenetics is nowadays increasingly incorporated in the clinic to better predict pharmacokinetics and optimize dosing regimens of drug treatments. While this approach has been successful and improved our prediction of drug metabolism, drug levels within patients may still commonly deviate between…
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Modeling interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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Managing a sustainable career in the contemporary world of work: Personal choices and contextual challenges
On 9 June 2020, Maral Darouei defended her thesis 'Managing a sustainable career in the contemporary world of work: Personal choices and contextual challenges'. The doctoral research was supervised by Prof. J.I. van der Rest.
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Proactive personality has stronger wake-sleep rhythm
Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.
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Combining classic and novel tools in the study of Historical Collections of Chinese Materia Medica in the Netherlands
Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…
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the neural correlates of Emotional Working Memory in Borderline Personality Disorder
How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?
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Making energy personal: policy coordination challenges in UK smart meter implementation
Governments are increasingly facilitating the roll-out of so-called “smart meters”, a technology for measuring energy consumption that are able to transmit and receive data using a form of electronic communication. However, implementation has been slow or even stalled.
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Leiden Professor convenes precision medicine workshop at Harvard's Radcliffe Institute
Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.
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New Master’s programme in Transfusion Medicine and Cellular and Tissue Therapies
LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.
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Lindsey Burggraaff wins KNCV poster prize at the FIGON Dutch Medicine Days
Drs. Lindsey Burggraaff wins KNCV poster prize in the category
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Bart Lenselink will represent LACDR at the FIGON Dutch Medicines Days
Drs. Bart Lenselink won the oral presentation at the LACDR Spring Symposium with his presentation “Predicting Drug Potency”.
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Leiden University/LUMC to drop cum laude honour for Master’s in Medicine
As of 1 September 2024, the cum laude honour will no longer be awarded for the Master’s in Medicine. The Executive Board recently decided to grant an exemption to the Leiden University/LUMC Faculty of Medicine. This decision is in line with other medicine programmes in the Netherlands.
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Working Memory training on emotion regulation capacities in Borderline Personality Disorder
Does an Emotional Working Memory Training show a beneficial transfer effect on emotion regulation (reappraisal) capacities in patients with Borderline Personality Disorder?
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Dr. Dong Guo won the Dutch Medicinal Chemistry prize 2013-2014
On March 27th, 2015 the biannual Dutch Medicinal Chemistry Prize for the best Dutch Ph.D. thesis in the field was awarded to Dr. Dong Guo, a current postdoc researcher in our lab, by the Section of Medicinal Chemistry of the Royal Netherlands Chemical Society.
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Indira Nederpelt was awarded best oral presentation at the FIGON Dutch Medicines Days 2014
Indira Nederpelt presented her work at the FIGON Dutch Medicines Days held on October 6 2014 in Ede and provided a kinetic perspective on the characterization of clinically used GnRH peptide agonists.
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Social Feedback and Emotion Regulation in Borderline Personality Disorder: An fMRI study
What is the role of emotion regulation in coping with interpersonal feedback?
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Dong Guo won two poster prizes at the FIGON Dutch Medicines Days
Dong Guo was awarded two poster prizes for his poster ‘Molecular Mechanism of Allosteric modulation at G protein-coupled Receptors: Insight from a Binding Kinetics Study at the Human A1 Adenosine Receptor’ at the FIGON Dutch Medicines Days, October 6th-8th this year.
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International Exhibition on Jamu: Medicinal Plants for Health and Conservation in Indonesia
In 2005, the LEAD Programme organised and coordinated the International Exhibition on ‘Jamu: Medicinal Plants for Health and Conservation in Indonesia’ in collaboration with Universitas Padjadjaran (UNPAD) in Bandung, Indonesia, the Mediterranean Agronomic Institute of Chania (MAICH) in Chania, Crete,…
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What do surgeons have in common? Their personality unravelled
Open, extravert, agreeable, stress-tolerant and conscientious. These are the character traits of surgeons according to research by the LUMC.
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LUMC first medical programme to include AI in curriculum
How do you make effective use of AI and medical technology? And what role do you play in this as a doctor? This is what the LUMC/Leiden University is preparing medical students for, right from the first year of their studies.
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How do you determine the right medicine dosage for a child?
What’s the right dosage of medication for children? Assistant professor Elke Krekels and her colleagues discovered that for some medicines, you can determine this quite simply. On 13 April Krekels received the TOP-Publication award during the annual spring meeting of the Dutch Society for Clinical Pharmacology…
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Disability: the Global Impact of the International Year of Disabled Persons (1981) in Historical Perspective
How did disability become a global concern? In this project we will identify the contribution of international agencies, governmental and non-governmental organizations and, just as importantly, disabled people themselves, to the IYDP and by showing the connections, interactions and entanglements between…
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Westen appointed as full Professor of Artificial Intelligence and Medicinal Chemistry
Gerard van Westen has been appointed full Professor or Artificial Intelligence and Medicinal Chemistry. This chair has been jointly created by the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Chemistry (LIC) as part of SAILS, the university stimulus program in Artificial…
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With this algorithm, new medicines can be found more quickly
Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…
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IBL coordinates project to search for new medicines in marine biodiversity
Gilles van Wezel of the Institute of Biology Leiden will lead a European consortium to search for new medicines and disease-suppressive microbes while preserving biodiversity. The consortium will explore the largely unknown potential of marine microorganisms.
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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The scientists behind LED3
LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.
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Mona Shahab
Faculteit der Sociale Wetenschappen