1,921 search results for “mathematics and statistical modelling” in the Public website
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Quantum local asymptotic normality and other questions of quantum statistics
Promotor: R. Gill, Co-promotor: P. Massart
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Why Leiden University?
You gain a strong foundation in computer science, combined with knowledge of machine learning, cognitive science, human-robot interaction. You will learn to develop and program systems based on knowledge of the human brain.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Predictive Pharmacology in Children using Semi-Physiological population modelling
An integrated approach of physiological concepts, advanced statistical approaches and large clinical datasets.
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Abstract Behavioral Specification: unifying modeling and programming
We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.
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Quantitative biology of polar auxin transport and plant development
The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
- Data Science & Artificial Intelligence
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Terry MostertFaculteit der Sociale Wetenschappen
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Light Weighed: On the Statistics and Systematics of Weak Gravitational Lensing
In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.
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and tissue dynamics with cell fate decisions through computational modeling
There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…
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Evaluating European imports of Asian aquaculture products using statistically supported life cycle assessments
Promotor: Prof.dr. G.R. de Snoo
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Peter Grünwald professor statistical learning
As of November 1st, Peter Grünwald has been appointed professor Statistical learning on a new chair hosted by both the Mathematical Institute and the Leiden Institute for Advanced Computer Science (LIACS).
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Duality, bosonic particle systems and some exactly solvable models of non-equilibrium
Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander
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Minimal structure modeling
Existing work in probabilistic language modeling can be mostly divided into two categories:
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Biotic ligand models
Description of Biotic ligand models: making an inventory of available models & assessment of the variability of the predicted HC5 using the BLMs in different Dutch water types (2005 - 2007)
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Twenty years of international mathematics master at Leiden
Mathematicians from Bordeaux, Leiden and Padua have been working together for 20 years. In 2004, they started a two-year mathematics master's degree in Algebra, Number Theory and Geometry (Algant). They celebrated the 20th anniversary of this consortium at the Algant graduation ceremony in Leiden.
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Strategic research into and development of best practice for, predictive modelling on behalf of Dutch Cultural Resource Management
Are predictive archaeological maps a reliable tool to play an important role in the spatial planning? One of the goals of this project was to develop best practices for the production and application of the models.
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The parabolic Anderson model on Galton-Watson trees
The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.
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Bioactivity based quality control for Chinese herbal medicine
Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?
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PhD: Modeling the mechanical regulation of plant development and regeneration (1.0 FTE)
Science, Mathematical Institute (MI)
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Postdoc Three-dimensional simulation models of plant tissue mechanobiology (1.0 FTE for three years)
Science, Mathematical Institute (MI)
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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PhD Competence Model
In 2016, Dutch University Medical Centres (UMCs) developed the self-evaluation tool based on the PhD Competence Model. Our partners at Utrecht University are making a digital version of the tool available free of charge for our PhD candidates at Leiden University, including for candidates who are not…
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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Animal models for cutaneous vaccine delivery
Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.
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Mathematics, medicine and teaching
Mathematician Stéphanie van der Pas, winner of the C.J. Kok Jury Award for her PhD thesis in 2017, divides her time between research and education, and between pure mathematics and practical application.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
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Data Science: Computer Science (MSc)
The master's specialisation Data Science: Computer Science at Leiden University provides students thorough knowledge and understanding of statistical and computational aspects of data analysis, including their application in databases, advances in data mining, networks, pattern recognition, and deep…
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Model painting with diverse techniques
Arts and leisure, Arts and leisure
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Data Driven Modeling & Optimization of Industrial Processes
Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.
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Modelling metastatic melanoma in zebrafish
Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.
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Ruben HueleScience
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Aad van der Vaart Scientific Director Mathematical Institute
Prof. dr. Aad van der Vaart has been appointed as Scientific Director of the Mathematical Institute of Leiden University on Tuesday 15 September 2015. He succeeds prof. dr. Peter Stevenhagen who has been a dedicated Scientific Director of the Mathematical Institute as from 2007.
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Data-Driven Drug Discovery Network (D4N)
The Data-Driven Drug Discovery Network (D4N) is an initiative by researchers from Leiden University and collaborators to join efforts in applying and developing novel techniques from data science to drug discovery and related topics from bioinformatics.
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Why Leiden University?
Our programmes are known for our scientifically based education and for our open atmosphere.
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Why Leiden University?
Our programmes are known for our scientifically based education and for our open atmosphere.
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Why Leiden University?
Our programmes are known for our scientifically based education and for our open atmosphere.
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Why Leiden University?
Our programmes are known for our scientifically based education and for our open atmosphere.
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Why Leiden University?
Our programmes are known for our scientifically based education and for our open atmosphere.
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Why Leiden University?
Our programmes are known for our scientifically based education and for our open atmosphere.
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Stepwise latent class analysis
The main methodological aspects of the use of stepwise LCA estimators under different circumstances.
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Abstract delta modeling: software product lines and beyond
Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke
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Professor Richard Gill at TEDxFlanders “Statistical Errors in Court”
In a recent TEDx Flanders event “Statistical Errors in Court”, Statistical Scientist Richard Gill speaks about the case of Lucia de Berk, a nurse found guilty of several murders based largely on statistics.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Data Science and Artificial Intelligence (BSc)
The focus of the Bachelor Data Science & Artificial Intelligence is on computer science, and its applications in Artificial Intelligence. You will receive a strong basis in mathematics, statistics and computer science, combined with advanced knowledge of machine learning, cognitive science, human-robot…
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Contact
You may contact LUXs through any of its members or secretariats of its participating institutes. You may also reach the steering group through its chair or secretariat.