Research on the process and construction of news stories about human rights issues in Latin American newspapers.

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…

Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?

Utilization of plant-originated products as new antibiotics

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

Environmental Humanities in the New Himalayas: Symbiotic Indigeneity, Commoning, Sustainability showcases how the eco-geological creativity of the earth is integrally woven into the landforms, cultures, and cosmovisions of modern Himalayan communities.

Protestant missionaries have provided the earliest and most detailed sources regarding the ritual art of the Papuan peoples of the Geelvink Bay.

Natural product inspired antibiotics to address resistance

This project suggests a reconceptualisation of pre- and non-capitalist imperial monetary policy, arguing that the existing literature about imperial financial flows has unnecessarily privileged ideas of largesse and seemingly chaotic monetary distribution. Using the divergent cases of the Roman Empire…

‘Schiedsgerichte in den Aussenverträgen der EU. Neue Entwicklungen unter Einbezug der institutionellen Verhandlungen Schweiz–EU’, Jusletter 28 May 2018

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

What is the relationship between outcomes of dynamic testing and cognitive flexibility in young children?

Acta Politica is the official journal of the Dutch Political Science Association.

Annually the Institute of Cultural Anthropology and Development Sociology awards the Speckmann prize for the best Fieldwork NL report, as well as the most accomplished master’s thesis.

The LUGO team is part of the Administration and Central Services department of the university, with it falling under the Strategy and Academic Affairs department. Naturally, it falls into the sustainability team of the University, which consists of two full-time employees alongside the LUGO Team. The…

A comprehensive analysis of the state of play, the design of monitoring mechanisms, and creation of a toolbox of support measures.

Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Jochem van den Boogert defended his thesis on 18 November 2015

On 29 June May 2022 Yujing Tan successfully defended a doctoral thesis and graduated.

Surreal Geographies recovers a forgotten archive of Holocaust representation. Examining art, literature, and film produced from the immediate postwar period up to the present moment, Kathryn L. Brackney investigates changing portrayals of Jewish victims and survivors.

What are the immediate and lasting effects of the colonial encounters on indigenous Caribbean cultures and societies and what were the intercultural dynamics that took place during the colonisation processes? How can the study of indigenous Caribbean histories contribute to a more sophisticated awareness…

The figure of the barbarian has captivated the Western imagination from Greek antiquity to the present. Since the 1990s, the rhetoric of civilization versus barbarism has taken center stage in Western political rhetoric and the media. But how can the longevity and popularity of this opposition be accounted…

How was the future United Nations Organization promoted to global publics during WW II?

This recently released book takes a critical view of conceptual issues and practical problems that inevitably emerge when ‘excellence’ takes center stage in science systems in the Global South. What is ‘excellent science’? And how to recognize and assess it? After decades of inquiry and debate there…

Can we bring novel treatment options to the clinic for UM patients with liver metastases?

Volume 4 and 5 of the Leiden series 'Dutch Sources on South Asia' are now available, written by Markus Vink (vol.4) and Carolien Stolte (vol.5).

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

Currently the focus of the project is the development of a tool that utilizes dimensionality reduction techniques in order to analyze and interpret the lexical and phonological variation between different sign languages. Additionally, the application of deep learning techniques for the extraction of…

- Which metabolites could be components of NADES? - How can we prove the presence of NADES in nature? - What are the roles of NADES in nature? - How to apply NADES in life sciences?

What socio-cultural transformations did indigenous communities in the Lesser Antilles undergo from the late precolonial to the early colonial period in response to Amerindian­ European-African cultural encounters? How did Amerindian populations realign themselves in response to the colonisation…

This book brings together a collection of emergent research that moves the debate on desistance beyond a general consideration of individual and social structural influences.

The book offers different theoretical perspectives to help examine the process of public sector reform. In addition it gives an overview of the major trends in the core areas of the functioning of the public sector.

PhD defence

Subproject of

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

On the 11th of June, Umberto Selva successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Umberto on this great result.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

In this study, Bibi van den Berg and Sanneke Kuipers from ISGA, explore the ways in which cyber-related incidents may lead to crises

We also conduct research to make meaningful contributions to society. For instance, by talking about our research, contributing to community projects or by inviting people to help us with our research. Scroll down and discover how Science and Society can mutually reinforce each other.

On the 23d of May, Sanne Rotmeijer successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sanne on this achievement!

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.

Following the terrorist attacks in Paris (November 2015) and Brussels (March 2016), Belgium’s counterterrorism policy has been heavily criticized – domestically and worldwide.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

Rising geopolitical tensions are causing states and national elites to innovate their use of the past for present-day political ends. This is certainly true for the People’s Republic of China, which prepares to celebrate its 75th anniversary in 2024 amid mounting superpower rivalry, ideological tensions…