644 search results for “bipolar disorder” in the Public website
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
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The development and prevention of social anxiety in youth
What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?
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SPRING
In this project we followed children of parents with an anxiety disorder. We wanted to examine how these children develop and try to better understand why it is that some children develop fears, whilst other children do not. In this project, we mainly focus on social anxiety disorder and panic disor…
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Special education and autism
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Executive deficits in relation to early reading and math development
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Teachers' use of progress data in planning and evaluating instruction for students with learning disabilities
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Clinical Psychology
Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.
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Mental health problems during COVID highly variable by symptom cluster and population group
People already diagnosed with a mental disorder before the COVID-19 pandemic did not show a disproportionate increase in symptoms afterwards. This is one result from the first systematic review of longitudinal studies following their study population from before to during the first eighteen months of…
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Attention for autism in girls
Autism spectrum disorders are more often diagnosed in boys than in girls. For Developmental Psychology professor Carolien Rieffe this raises the question whether autism remains undiscovered in girls and women.
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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Growth and Transport properties of (Rare Earth)TiO3 / SrTiO3 interfaces
This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.
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Programme structure
The research master's specialisation Developmental Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
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Effects of noninvasive vagus nerve stimulation on perseverative cognition
Can excessive worrying be reduced via stimulation of the vagus nerve?
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Alice in Wonderland-syndrome
FSW Professor Jan Dirk Blom has written a book on Alice in Wonderland syndrome. This is the first scientific book on this rare disorder, which was first described in 1955 by the British psychiatrist John Todd. Todd was inspired by the famous book by Lewis Carroll, in which Alice experiences all kinds…
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Mast cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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LEF grant for Semiha Aydin to pilot social anxiety treatment
Semiha Aydin is one of the three first-generation researchers who received a grant from the Leiden Empowerment Fund to stimulate their scientific career.
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Siuman Chung
Faculteit der Sociale Wetenschappen
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Evert Scholte
Faculteit der Sociale Wetenschappen
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Christine Espin
Faculteit der Sociale Wetenschappen
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Bianca Boyer
Faculteit der Sociale Wetenschappen
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Jochanan Veerbeek
Faculteit der Sociale Wetenschappen
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Marit Guda
Faculteit der Sociale Wetenschappen
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Greta Noordenbos
Faculteit der Sociale Wetenschappen
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Neeltje van den Bedem
Faculteit der Sociale Wetenschappen
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Elise Swart
Faculteit der Sociale Wetenschappen
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Novel chemical tools for target validation in neuroinflammation
In what way can new tools and techniques be used to develop drug candidates for the treatment of neurological disorders?
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About us
All living creatures have to cope with environmental demands and threats that challenge their physical or emotional homeostasis.
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The role of zebrafish (Danio rerio) larvae in developing new drug candidates for treating anxiety, from natural sources
Can zebrafish larvae be used as a behavioural model for screening natural products as potential neurotropic drugs?
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Neurodevelopmental risks in young children with an extra X or Y chromosome
This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.
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Sexual responses can be learned and unlearned
Undesirable associations with sex can be unlearned, but return if the circumstances change. They must therefore be unlearned in different situations. The drug D-cycloserine may help here. These are the findings of psychologist Mirte Brom.
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The power of positive peers for socially anxious youth
Can positive peer feedback break the cycle of negative self-relevant cognitive processes and reduce self-reported anxiety in early adolescents?
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Chemical biology of sphingolipids: fundamental studies and clinical applications
Overkleeft
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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Presentations and Lectures
Members of our research team give different types of presentations and lectures.
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Willem van der Does
Faculteit der Sociale Wetenschappen
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Hanna Swaab
Faculteit der Sociale Wetenschappen
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Ellen de Bruijn
Faculteit der Sociale Wetenschappen
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Looking back at the Lorentz Workshop
“Endophenotypes of Social Anxiety Disorder: Can we detect them and are they useful in clinical practice”
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Brain changes underlying social anxiety: numbers count!
In a recent mega-analysis, researchers from Leiden University aimed to clarify the contradictory findings of research into social anxiety disorder. They found that to obtain reliable research results having the largest possible sample size is important. Publication in NeuroImage:Clinical.
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Youth mental health meets big data analytics: Hype or Hope?
Depression and anxiety disorders among youth are causing major problems worldwide. The mechanisms involved are still unknown, however. Moji Aghajani – Assistant Professor at the Institute of Education and Child Studies - aims to provide new insights with his research
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Empathic or anxious mistakes?
Empathic or anxious mistakes? A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments
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ISA - Intervention for Social Anxiety in children and youth
Social anxiety disorder is one of the most common disorders in children and young people. Social anxiety is characterized by excessive fear and avoidance of social situations. The primary fear in children with social anxiety is that they will be negatively judged by others. To date, the most frequently…
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Changing minds in social anxiety: A developmental network approach to neurocognitive bias modification
Which adolescents are more at risk of developing social anxiety disorder later in life?
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Cool little kids
Effectiveness of an early intervention program for anxiety-prone toddlers in the Netherlands
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Mood variability during adolescent development and its relation to sleep and brain development
During adolescence, mood disorder onset peaks. Mood variability is associated with negative mental health outcomes, so understanding biological factors that might be associated with mood variability, such as sleep and structural brain development, could elucidate the mechanisms underlying mood and anxiety…
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Self-regulation in boys with ODD/CD
Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior