Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

The rise and fall of the cesspit in an urban context

The figure of the barbarian has captivated the Western imagination from Greek antiquity to the present. Since the 1990s, the rhetoric of civilization versus barbarism has taken center stage in Western political rhetoric and the media. But how can the longevity and popularity of this opposition be accounted…

This volume challenges the idea that the development of ‘democracy’ is a story of rise and progress at all. It is rather a story of continuous but never completely satisfying attempts of interpreting the rule of the people.

How was anti-communism organized in the West? New volume edited by Giles Scott-Smith, Luc van Dongen and Stephanie Roulin on the aims, arguments and associations of a range of transnational anti-communist activists during the Cold War.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

In this article, Meier & Nadler suggest that while non-citizen enfranchisement boosts participation across all citizens, citizens with immigration backgrounds are more reactive to the NCV rights in terms of higher turnout. In this way, the paper adds a critical nuance to individual-based explanations…

In this paper, Andrea Malaya M. Ragragio and Myfel D. Paluga recast new light on the historical tattooing of the “Pintados,” or the the name by which the inhabitants of the Visayas Islands (in the central Philippines) were called by Spanish documenters in the sixteenth century. This is one of their…

Promotores: Prof.dr. J. Zaanen & Prof.dr. K.E. Schalm

Study information, Online Experience

The role of domestic and wild resource exploitation in Bronze Age subsistence

The research reported in this thesis is concerned with the knowledge development of a small sample of experienced science teachers in the context of a broad innovation in Dutch secondary education, including the introduction of a new syllabus on Public Understanding of Science.

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

Study information, Online Experience

What is your preferred career path? Would you like to teach? Do you enjoy doing research? Would you like to work in policy development, or are you interested in a job that involves writing and editing? You will find that your African Studies degree is a good preparation for the career of your choice…

Carl Li defended his thesis on 30 June 2015

In this dissertation, Dutch secondary school teachers’ attitudes, knowledge, noticing skills and reasoned practices regarding culturally responsive teaching in a multicultural classroom context, were examined.

This study presents the first systematic investigation and detailed theoretical analysis of the temporal interpretations of sentences with bare (aspectually unmarked) predicates in Mandarin.

This collection of essays details the political life of one of the most prominent and gifted American statesmen of the twentieth century. From his early training in international law to his five terms in the US Senate, J. William Fulbright (1905--1995) had a profound influence on US foreign policy,…

Jinhua Wu defended his thesis on 5 January 2021

On 20 January 2022, Marco Stam defended the thesis 'Essays on Welfare Benefits, Employment, and Crime'. The doctoral research was supervised by Prof. M.G. Knoef.

The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

This research aims to address the connection between Sufism and modern Arabic Literature (specifically, Palestinian literature).

In this article, Jeanine de Roy van Zuijdewijn and Edwin Bakker provide a big picture reflection on two decades after 9/11 in Western Europe.

Law and peace in the work of Hans Kelsen. A re-evaluation of Kelsen’s legal philosophy: legal pacifism as tacit meaning of his Pure Theory of Law

Chaider Bamualim defended his thesis on 9 September 2015

Can we identify different degrees of economic integration, both within and between regions, on the basis of archaeological proxies?

Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

On young Muslims seeking to understand their place and make their way in a transformed world.

Promotor: Prof.dr. M. Danhof

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

In this study I explore literary structures of identity-formation in the works of assimilated/acculturated Jewish writers: Kafka’s novella “The Metamorphosis” (“Die Verwandlung”, 1912) and David Vogel’s Hebrew novel Married Life. 1929).

In this study Lilie Roosman describes the effects of prominence and boundary marking on the temporal and melodic structures of two regional languages of Indonesia, viz. Toba Batak, a stress language, and her native language Betawi Malay, a non-stress language.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

On 1 July 2020, Niek Strohmaier defended his thesis 'Making Sense of Business Failure'. The doctoral research was supervised by Prof. J.A.A. Adriaanse en dr. H. Pluut.

This article presents two related arguments. First, the limits of doctrinal analysis cut deeper than many EU lawyers realise. Most would probably accept that legal doctrine does not determine every legal dispute, but lawyers studying EU institutional balance often still assume that it can be deduced…

This volume edited by Jan Lucassen and Leo Lucassen aims to quantify and qualify cross-cultural global migrations and was published in the series 'Studies in Global Migration History'.

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Making an impact by creating solutions for the challenges of the future. That’s what we do at the Faculty of Science through our education and research in biodiversity and sustainability, artificial intelligence, complex networks, new medicines, quantum technology, and galaxies.

Smartphone behaviors are so common but how does the brain generate this behavior? The Cognition in the digital environment laboratory (CODELAB) investigated the brain activity surrounding smartphone interactions with the help of Artificial Intelligence. According to their research, the brain fluidly…

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.